Detalhe da pesquisa
1.
Mitochondrial ClpX Activates a Key Enzyme for Heme Biosynthesis and Erythropoiesis.
Cell
; 161(4): 858-67, 2015 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25957689
2.
The RNA helicase DDX3 induces neural crest by promoting AKT activity.
Development
; 148(2)2021 01 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33318149
3.
Peristaltic pumps adapted for laminar flow experiments enhance in vitro modeling of vascular cell behavior.
J Biol Chem
; 298(10): 102404, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35988646
4.
Metalloprotease ADAM9 cleaves ephrin-B ligands and differentially regulates Wnt and mTOR signaling downstream of Akt kinase in colorectal cancer cells.
J Biol Chem
; 298(8): 102225, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35780836
5.
The ubiquitous mitochondrial protein unfoldase CLPX regulates erythroid heme synthesis by control of iron utilization and heme synthesis enzyme activation and turnover.
J Biol Chem
; 297(2): 100972, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34280433
6.
Mutation in human CLPX elevates levels of δ-aminolevulinate synthase and protoporphyrin IX to promote erythropoietic protoporphyria.
Proc Natl Acad Sci U S A
; 114(38): E8045-E8052, 2017 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28874591
7.
FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity.
J Biol Chem
; 293(51): 19797-19811, 2018 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30366982
8.
Reductions in the mitochondrial ABC transporter Abcb10 affect the transcriptional profile of heme biosynthesis genes.
J Biol Chem
; 292(39): 16284-16299, 2017 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28808058
9.
Macrocytic anemia and mitochondriopathy resulting from a defect in sideroflexin 4.
Am J Hum Genet
; 93(5): 906-14, 2013 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24119684
10.
A mutation in the iron-responsive element of ALAS2 is a modifier of disease severity in a patient suffering from CLPX associated erythropoietic protoporphyria.
Haematologica
; 106(7): 2030-2033, 2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33596641
11.
Characterization of genomic deletion efficiency mediated by clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 nuclease system in mammalian cells.
J Biol Chem
; 289(31): 21312-24, 2014 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24907273
12.
A role for iron deficiency in dopaminergic neurodegeneration.
Proc Natl Acad Sci U S A
; 113(13): 3417-8, 2016 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26984501
13.
Functional interactions between erythroid Krüppel-like factor (EKLF/KLF1) and protein phosphatase PPM1B/PP2Cß.
J Biol Chem
; 287(19): 15193-204, 2012 May 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-22393050
14.
Characterization of genomic deletion efficiency mediated by clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 nuclease system in mammalian cells.
J Biol Chem
; 292(6): 2556, 2017 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28188222
15.
FAM210B is dispensable for erythroid differentiation in adult mice.
bioRxiv
; 2023 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37823037
16.
Regulation of Heme Synthesis by Mitochondrial Homeostasis Proteins.
Front Cell Dev Biol
; 10: 895521, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35832791
17.
Restored iron transport by a small molecule promotes absorption and hemoglobinization in animals.
Science
; 356(6338): 608-616, 2017 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28495746
18.
Mitochondrial transport of protoporphyrinogen IX in erythroid cells.
Oncotarget
; 6(25): 20742-3, 2015 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26369700
19.
Alternative splicing of EKLF/KLF1 in murine primary erythroid tissues.
Exp Hematol
; 43(1): 65-70, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25283745
20.
The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability.
Sci Signal
; 8(372): ra34, 2015 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25872869