Detalhe da pesquisa
1.
Thousands of conductance levels in memristors integrated on CMOS.
Nature
; 615(7954): 823-829, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36991190
2.
Design, synthesis, and biological evaluation of aminopyridine derivatives as novel tropomyosin receptor kinase inhibitors.
Arch Pharm (Weinheim)
; 356(3): e2200438, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36398500
3.
Effect of Electrospinning Network Instead of Polymer Network on the Properties of PDLCs.
Molecules
; 28(8)2023 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37110605
4.
Therapeutic potential of targeting LSD1/ KDM1A in cancers.
Pharmacol Res
; 175: 105958, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34718134
5.
Design, synthesis, and biological evaluation of potent FAK-degrading PROTACs.
J Enzyme Inhib Med Chem
; 37(1): 2241-2255, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-35978496
6.
Design, synthesis, and evaluation of novel 3,4-isoxazolediamide derivatives for the combination treatment of azole-resistant candidiasis.
Arch Pharm (Weinheim)
; 355(12): e2200266, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36029272
7.
Discovery of 2,4-diaminopyrimidine derivatives targeting p21-activated kinase 4: Biological evaluation and docking studies.
Arch Pharm (Weinheim)
; 353(10): e2000097, 2020 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-32627873
8.
Discovery of 2-(4-Substituted-piperidin/piperazine-1-yl)-N-(5-cyclopropyl-1H-pyrazol-3-yl)-quinazoline-2,4-diamines as PAK4 Inhibitors with Potent A549 Cell Proliferation, Migration, and Invasion Inhibition Activity.
Molecules
; 23(2)2018 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29443911
9.
Nanozyme-Based Regulation of Cellular Metabolism and Their Applications.
Adv Mater
; 36(10): e2301810, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-37017586
10.
Programming memristor arrays with arbitrarily high precision for analog computing.
Science
; 383(6685): 903-910, 2024 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38386733
11.
Green Preparation of Lightweight, High-Strength Cellulose-Based Foam and Evaluation of Its Adsorption Properties.
Polymers (Basel)
; 15(8)2023 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37112026
12.
Design, synthesis, and biological evaluation of diaminopyrimidine derivatives as novel focal adhesion kinase inhibitors.
RSC Med Chem
; 14(11): 2301-2314, 2023 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37974962
13.
Discovery of CZS-241: A Potent, Selective, and Orally Available Polo-Like Kinase 4 Inhibitor for the Treatment of Chronic Myeloid Leukemia.
J Med Chem
; 66(4): 2396-2421, 2023 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36734825
14.
Discovery of the First Potent, Selective, and In Vivo Efficacious Polo-like Kinase 4 Proteolysis Targeting Chimera Degrader for the Treatment of TRIM37-Amplified Breast Cancer.
J Med Chem
; 66(12): 8200-8221, 2023 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37279162
15.
Broadening antifungal spectrum and improving metabolic stablity based on a scaffold strategy: Design, synthesis, and evaluation of novel 4-phenyl-4,5-dihydrooxazole derivatives as potent fungistatic and fungicidal reagents.
Eur J Med Chem
; 227: 113955, 2022 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34749201
16.
Rational drug design to explore the structure-activity relationship (SAR) of TRK inhibitors with 2,4-diaminopyrimidine scaffold.
Eur J Med Chem
; 230: 114096, 2022 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35007864
17.
Design, synthesis, and biological activity evaluation of 2-(benzo[b]thiophen-2-yl)-4-phenyl-4,5-dihydrooxazole derivatives as broad-spectrum antifungal agents.
Eur J Med Chem
; 228: 113987, 2022 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34801270
18.
Discovery of quinazoline derivatives CZw-124 as a pan-TRK inhibitor with potent anticancer effects in vitro and in vivo.
Eur J Med Chem
; 238: 114451, 2022 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35617855
19.
Identification of novel indole derivatives as highly potent and efficacious LSD1 inhibitors.
Eur J Med Chem
; 239: 114523, 2022 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35732082
20.
Structure-based discovery of 1-(3-fluoro-5-(5-(3-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)phenyl)-3-(pyrimidin-5-yl)urea as a potent and selective nanomolar type-II PLK4 inhibitor.
Eur J Med Chem
; 243: 114714, 2022 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36063666