Detalhe da pesquisa
1.
Photo-regulated PROTACs: A novel tool for temporal control of targeted protein degradation.
Bioorg Med Chem Lett
; 107: 129778, 2024 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38702019
2.
Expansion of targeted degradation by Gilteritinib-Warheaded PROTACs to ALK fusion proteins.
Bioorg Chem
; 145: 107204, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38377822
3.
Rapid Structure Determination of Ranitidine Hydrochloride API in Two Crystal Forms Using Microcrystal Electron Diffraction.
Chem Pharm Bull (Tokyo)
; 72(5): 471-474, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38749738
4.
Rational Design of Amphipathic Antimicrobial Peptides with Alternating L-/D-Amino Acids That Form Helical Structures.
Chem Pharm Bull (Tokyo)
; 72(2): 149-154, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38296556
5.
In Silico Prediction of N-Nitrosamine Formation Pathways of Pharmaceutical Products.
Chem Pharm Bull (Tokyo)
; 72(2): 166-172, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38296559
6.
Effect of helicity and hydrophobicity on cell-penetrating ability of arginine-rich peptides.
Bioorg Med Chem
; 91: 117409, 2023 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37441862
7.
Advanced Solid-State NMR Analysis of Two Crystal Forms of Ranitidine Hydrochloride: Detection of 1H-14N Intra-/Intermolecular Correlations.
Chem Pharm Bull (Tokyo)
; 71(1): 58-63, 2023 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36288936
8.
An Amphipathic Structure of a Dipropylglycine-Containing Helical Peptide with Sufficient Length Enables Safe and Effective Intracellular siRNA Delivery.
Chem Pharm Bull (Tokyo)
; 71(3): 250-256, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36858531
9.
Development of Hydrophobic Cell-Penetrating Stapled Peptides as Drug Carriers.
Int J Mol Sci
; 24(14)2023 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37511527
10.
Fcγ Receptor-Dependent Internalization and Off-Target Cytotoxicity of Antibody-Drug Conjugate Aggregates.
Pharm Res
; 39(1): 89-103, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-34961908
11.
Development of delivery carriers for plasmid DNA by conjugation of a helical template to oligoarginine.
Bioorg Med Chem
; 72: 116997, 2022 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36088811
12.
Recent Advances in PROTAC Technology Toward New Therapeutic Modalities.
Chem Biodivers
; 19(11): e202200828, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36124821
13.
Synthesis of Norgestomet and its 17ß-isomer and evaluation of their agonistic activities against progesterone receptor.
Bioorg Med Chem
; 49: 116425, 2021 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34607200
14.
Structure-activity relationship study of amphipathic antimicrobial peptides using helix-destabilizing sarcosine.
J Pept Sci
; 27(12): e3360, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34164880
15.
N-Nitrosodimethylamine (NDMA) Formation from Ranitidine Impurities: Possible Root Causes of the Presence of NDMA in Ranitidine Hydrochloride.
Chem Pharm Bull (Tokyo)
; 69(9): 872-876, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34470951
16.
Peptide Stapling Improves the Sustainability of a Peptide-Based Chimeric Molecule That Induces Targeted Protein Degradation.
Int J Mol Sci
; 22(16)2021 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34445478
17.
Development of Antimicrobial Stapled Peptides Based on Magainin 2 Sequence.
Molecules
; 26(2)2021 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33466998
18.
De Novo Design of Cell-Penetrating Foldamers.
Chem Rec
; 20(9): 912-921, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-32463155
19.
Design and synthesis of peptide-based chimeric molecules to induce degradation of the estrogen and androgen receptors.
Bioorg Med Chem
; 28(15): 115595, 2020 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32631565
20.
Development of Photoswitchable Estrogen Receptor Ligands.
Chem Pharm Bull (Tokyo)
; 68(4): 398-402, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32238658