Detalhe da pesquisa
1.
Novel 3-fluoro-6-methoxyquinoline derivatives as inhibitors of bacterial DNA gyrase and topoisomerase IV.
Bioorg Med Chem Lett
; 27(15): 3353-3358, 2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28610977
2.
Novel quinoline derivatives as inhibitors of bacterial DNA gyrase and topoisomerase IV.
Bioorg Med Chem Lett
; 23(10): 2955-61, 2013 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23566517
3.
Discovery, synthesis and SAR of azinyl- and azolylbenzamides antagonists of the P2X7 receptor.
Bioorg Med Chem Lett
; 21(18): 5475-9, 2011 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21782426
4.
Optimization of the physicochemical and pharmacokinetic attributes in a 6-azauracil series of P2X7 receptor antagonists leading to the discovery of the clinical candidate CE-224,535.
Bioorg Med Chem Lett
; 21(12): 3708-11, 2011 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21565499
5.
PF-03814735, an orally bioavailable small molecule aurora kinase inhibitor for cancer therapy.
Mol Cancer Ther
; 9(4): 883-94, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20354118
6.
Flavin-containing monooxygenase activity in hepatocytes and microsomes: in vitro characterization and in vivo scaling of benzydamine clearance.
Drug Metab Dispos
; 30(10): 1087-93, 2002 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12228184
7.
Novel CCR1 antagonists with improved metabolic stability.
Bioorg Med Chem Lett
; 14(9): 2175-9, 2004 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-15081003
8.
Prevention of organ allograft rejection by a specific Janus kinase 3 inhibitor.
Science
; 302(5646): 875-8, 2003 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-14593182