Detalhe da pesquisa
1.
Akt and 14-3-3 control a PACS-2 homeostatic switch that integrates membrane traffic with TRAIL-induced apoptosis.
Mol Cell
; 34(4): 497-509, 2009 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-19481529
2.
The BCR-ABL35INS insertion/truncation mutant is kinase-inactive and does not contribute to tyrosine kinase inhibitor resistance in chronic myeloid leukemia.
Blood
; 118(19): 5250-4, 2011 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-21908430
3.
Appl1 is dispensable for mouse development, and loss of Appl1 has growth factor-selective effects on Akt signaling in murine embryonic fibroblasts.
J Biol Chem
; 285(9): 6377-89, 2010 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-20040596
4.
Appl1 is dispensable for Akt signaling in vivo and mouse T-cell development.
Genesis
; 48(9): 531-9, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20665729
5.
Human and mouse mesotheliomas exhibit elevated AKT/PKB activity, which can be targeted pharmacologically to inhibit tumor cell growth.
Oncogene
; 24(40): 6080-9, 2005 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-15897870
6.
Threshold levels of ABL tyrosine kinase inhibitors retained in chronic myeloid leukemia cells determine their commitment to apoptosis.
Cancer Res
; 73(11): 3356-70, 2013 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23576564
7.
HIV-1 Nef binds PACS-2 to assemble a multikinase cascade that triggers major histocompatibility complex class I (MHC-I) down-regulation: analysis using short interfering RNA and knock-out mice.
J Biol Chem
; 283(17): 11772-84, 2008 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-18296443
8.
A homeostatic switch in PACS-2 links membrane traffic to TRAIL-induced apoptosis.
Cell Cycle
; 8(17): 2679-80, 2009 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19690460
9.
Role of extracellular signal-regulated kinase pathway in RRR-alpha-tocopheryl succinate-induced differentiation of human MDA-MB-435 breast cancer cells.
Mol Carcinog
; 33(4): 228-36, 2002 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-11933076