Detalhe da pesquisa
1.
Apolipoprotein E regulates lipid metabolism and α-synuclein pathology in human iPSC-derived cerebral organoids.
Acta Neuropathol
; 142(5): 807-825, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34453582
2.
Integrative functional genomic analysis of intron retention in human and mouse brain with Alzheimer's disease.
Alzheimers Dement
; 17(6): 984-1004, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33480174
3.
Plasma amyloid ß levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome-wide association study in over 12,000 non-demented participants.
Alzheimers Dement
; 17(10): 1663-1674, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34002480
4.
APOE ε4/ε4 diminishes neurotrophic function of human iPSC-derived astrocytes.
Hum Mol Genet
; 26(14): 2690-2700, 2017 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28444230
5.
Brain Perivascular Macrophages Initiate the Neurovascular Dysfunction of Alzheimer Aß Peptides.
Circ Res
; 121(3): 258-269, 2017 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28515043
6.
Divergent brain gene expression patterns associate with distinct cell-specific tau neuropathology traits in progressive supranuclear palsy.
Acta Neuropathol
; 136(5): 709-727, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30136084
7.
Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases.
Alzheimers Dement
; 14(3): 352-366, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29107053
8.
ABCA7 Deficiency Accelerates Amyloid-ß Generation and Alzheimer's Neuronal Pathology.
J Neurosci
; 36(13): 3848-59, 2016 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-27030769
9.
Genetics of CD33 in Alzheimer's disease and acute myeloid leukemia.
Hum Mol Genet
; 24(12): 3557-70, 2015 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25762156
10.
Correction to: Apolipoprotein E regulates lipid metabolism and αsynuclein pathology in human iPSCderived cerebral organoids.
Acta Neuropathol
; 143(1): 119-121, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-34724591
11.
Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.
PLoS Genet
; 10(9): e1004606, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25188341
12.
A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression.
Alzheimers Dement
; 13(6): 663-673, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-27939925
13.
Transethnic genome-wide scan identifies novel Alzheimer's disease loci.
Alzheimers Dement
; 13(7): 727-738, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28183528
14.
Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2).
J Biol Chem
; 290(43): 26043-50, 2015 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26374899
15.
TREM2 variants in Alzheimer's disease.
N Engl J Med
; 368(2): 117-27, 2013 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-23150934
16.
Gene expression, methylation and neuropathology correlations at progressive supranuclear palsy risk loci.
Acta Neuropathol
; 132(2): 197-211, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27115769
17.
Innate immunity receptor CD36 promotes cerebral amyloid angiopathy.
Proc Natl Acad Sci U S A
; 110(8): 3089-94, 2013 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-23382216
18.
The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease.
Nat Genet
; 39(2): 168-77, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17220890
19.
Uncoupling of endothelial nitric oxide synthase in cerebral vasculature of Tg2576 mice.
J Neurochem
; 134(6): 1129-38, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26111938
20.
Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants.
PLoS Genet
; 8(6): e1002707, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22685416