Detalhe da pesquisa
1.
Clinical targeting of HIV capsid protein with a long-acting small molecule.
Nature
; 584(7822): 614-618, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32612233
2.
Preclinical characterization of a non-peptidomimetic HIV protease inhibitor with improved metabolic stability.
Antimicrob Agents Chemother
; 68(4): e0137323, 2024 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38380945
3.
Lenacapavir: A Novel, Potent, and Selective First-in-Class Inhibitor of HIV-1 Capsid Function Exhibits Optimal Pharmacokinetic Properties for a Long-Acting Injectable Antiretroviral Agent.
Mol Pharm
; 20(12): 6213-6225, 2023 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37917742
4.
A potent nuclear export mechanism imposes USP16 cytoplasmic localization during interphase.
J Cell Sci
; 133(4)2020 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32005696
5.
Cytopathological review of cervical pathology: Impact for women and follow-up results.
Aust N Z J Obstet Gynaecol
; 60(3): 444-448, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32080827
6.
Nationwide Trends in Acute and Chronic Pancreatitis Among Privately Insured Children and Non-Elderly Adults in the United States, 2007-2014.
Gastroenterology
; 155(2): 469-478.e1, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29660323
7.
A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes.
PLoS Pathog
; 12(4): e1005545, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-27082643
8.
A Role for CHH Methylation in the Parent-of-Origin Effect on Altered Circadian Rhythms and Biomass Heterosis in Arabidopsis Intraspecific Hybrids.
Plant Cell
; 26(6): 2430-2440, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24894042
9.
Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair.
Proc Natl Acad Sci U S A
; 111(1): 285-90, 2014 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24347639
10.
The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer.
J Biol Chem
; 290(48): 28643-63, 2015 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-26416890
11.
Antiviral Activity of Bictegravir (GS-9883), a Novel Potent HIV-1 Integrase Strand Transfer Inhibitor with an Improved Resistance Profile.
Antimicrob Agents Chemother
; 60(12): 7086-7097, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27645238
12.
Role of Mitochondrial RNA Polymerase in the Toxicity of Nucleotide Inhibitors of Hepatitis C Virus.
Antimicrob Agents Chemother
; 60(2): 806-17, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26596942
13.
Histone deacetylase inhibitor romidepsin induces HIV expression in CD4 T cells from patients on suppressive antiretroviral therapy at concentrations achieved by clinical dosing.
PLoS Pathog
; 10(4): e1004071, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24722454
14.
ß-PIX controls intracellular viscoelasticity to regulate lung cancer cell migration.
J Cell Mol Med
; 19(5): 934-47, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25683605
15.
Study of marine natural products including resorcyclic acid lactones from Humicola fuscoatra that reactivate latent HIV-1 expression in an in vitro model of central memory CD4+ T cells.
J Nat Prod
; 77(3): 618-24, 2014 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24495105
16.
Crosstalk between O-GlcNAcylation and proteolytic cleavage regulates the host cell factor-1 maturation pathway.
Proc Natl Acad Sci U S A
; 108(7): 2747-52, 2011 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21285374
17.
High-viscosity driven modulation of biomechanical properties of human mesenchymal stem cells promotes osteogenic lineage.
Mater Today Bio
; 26: 101058, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38681057
18.
Matrix mechanics regulates muscle regeneration by modulating kinesin-1 activity.
Biomaterials
; 308: 122551, 2024 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-38593710
19.
Geometric Deep Learning for Structure-Based Ligand Design.
ACS Cent Sci
; 9(12): 2257-2267, 2023 Dec 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38161364
20.
Design and Synthesis of Novel HIV-1 NNRTIs with Bicyclic Cores and with Improved Physicochemical Properties.
J Med Chem
; 66(3): 1761-1777, 2023 02 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36652602