Detalhe da pesquisa
1.
A 2D LC-MS/MS Strategy for Reliable Detection of 10-ppm Level Residual Host Cell Proteins in Therapeutic Antibodies.
Anal Chem
; 90(22): 13365-13372, 2018 11 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30345749
2.
Domain-specific free thiol variant characterization of an IgG1 by reversed-phase high-performance liquid chromatography mass spectrometry.
Anal Biochem
; 519: 8-14, 2017 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27940013
3.
Absolute Quantitation of Intact Recombinant Antibody Product Variants Using Mass Spectrometry.
Anal Chem
; 87(20): 10475-82, 2015 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26376221
4.
More similar than different: Host cell protein production using three null CHO cell lines.
Biotechnol Bioeng
; 112(10): 2068-83, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25894672
5.
Recombinant antibody color resulting from advanced glycation end product modifications.
Anal Chem
; 86(19): 9816-23, 2014 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25181536
6.
Eliminating tyrosine sequence variants in CHO cell lines producing recombinant monoclonal antibodies.
Biotechnol Bioeng
; 110(4): 1087-97, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23108857
7.
A ribonucleoprotein-based decaplex CRISPR/Cas9 knockout strategy for CHO host engineering.
Biotechnol Prog
; 38(1): e3212, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34538022
8.
Attribute Analytics Performance Metrics from the MAM Consortium Interlaboratory Study.
J Am Soc Mass Spectrom
; 33(9): 1659-1677, 2022 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36018776
9.
Accurate determination of succinimide degradation products using high fidelity trypsin digestion peptide map analysis.
Anal Chem
; 83(15): 5912-9, 2011 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21692515
10.
Scientific Best Practices for Primary Sequence Confirmation and Sequence Variant Analysis in the Development of Therapeutic Proteins.
J Pharm Sci
; 110(2): 619-626, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33212163
11.
New Peak Detection Performance Metrics from the MAM Consortium Interlaboratory Study.
J Am Soc Mass Spectrom
; 32(4): 913-928, 2021 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33710905
12.
Mechanisms of unintended amino acid sequence changes in recombinant monoclonal antibodies expressed in Chinese Hamster Ovary (CHO) cells.
Biotechnol Bioeng
; 107(1): 163-71, 2010 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20506532
13.
Identification of codon-specific serine to asparagine mistranslation in recombinant monoclonal antibodies by high-resolution mass spectrometry.
Anal Chem
; 81(22): 9282-90, 2009 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19852494
14.
A Rapid High-Sensitivity Reversed-Phase Ultra High Performance Liquid Chromatography Mass Spectrometry Method for Assessing Polysorbate 20 Degradation in Protein Therapeutics.
J Pharm Sci
; 108(9): 2880-2886, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31054888
15.
A modular and adaptive mass spectrometry-based platform for support of bioprocess development toward optimal host cell protein clearance.
MAbs
; 9(4): 654-663, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28346045
16.
Strain engineering to prevent norleucine incorporation during recombinant protein production in Escherichia coli.
Biotechnol Prog
; 31(1): 204-11, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25315437