Detalhe da pesquisa
1.
A Phase I Dose-Escalation Study of LY3405105, a Covalent Inhibitor of Cyclin-Dependent Kinase 7, Administered to Patients With Advanced Solid Tumors.
Oncologist
; 29(1): e131-e140, 2024 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37531083
2.
Phase 1 study to evaluate Crenigacestat (LY3039478) in combination with dexamethasone in patients with T-cell acute lymphoblastic leukemia and lymphoma.
Cancer
; 127(3): 372-380, 2021 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33107983
3.
Phase 1 study of 2 high dose intensity schedules of the pan-Notch inhibitor crenigacestat (LY3039478) in combination with prednisone in patients with advanced or metastatic cancer.
Invest New Drugs
; 39(1): 193-201, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32915419
4.
A phase 1b study of the Notch inhibitor crenigacestat (LY3039478) in combination with other anticancer target agents (taladegib, LY3023414, or abemaciclib) in patients with advanced or metastatic solid tumors.
Invest New Drugs
; 39(4): 1089-1098, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33686452
5.
Aurora kinase A inhibitor, LY3295668 erbumine: a phase 1 monotherapy safety study in patients with locally advanced or metastatic solid tumors.
Invest New Drugs
; 39(4): 1001-1010, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33479856
6.
Molecular and Epigenetic Mechanisms for the Complex Effects of Stress on Synaptic Physiology and Cognitive Functions.
Int J Neuropsychopharmacol
; 20(11): 948-955, 2017 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29016816
7.
Synergistic regulation of glutamatergic transmission by serotonin and norepinephrine reuptake inhibitors in prefrontal cortical neurons.
J Biol Chem
; 289(36): 25177-85, 2014 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25056951
8.
Restoration of glutamatergic transmission by dopamine D4 receptors in stressed animals.
J Biol Chem
; 288(36): 26112-26120, 2013 Sep 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-23884421
9.
Assembly of a beta2-adrenergic receptor--GluR1 signalling complex for localized cAMP signalling.
EMBO J
; 29(2): 482-95, 2010 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-19942860
10.
Handling missing data in a duloxetine population pharmacokinetic/pharmacodynamic model - imputation methods and selection models.
Pharm Res
; 31(10): 2829-43, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24792830
11.
Novel CHATogether family-centered mental health care in the post-pandemic era: a pilot case and evaluation.
Child Adolesc Psychiatry Ment Health
; 18(1): 57, 2024 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38773657
12.
Homeostatic regulation of glutamatergic transmission by dopamine D4 receptors.
Proc Natl Acad Sci U S A
; 107(51): 22308-13, 2010 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-21135234
13.
Navigating Intersectional Identities: Clinical Considerations for Working With LGBTQ Asian American Youth.
J Am Acad Child Adolesc Psychiatry
; 62(12): 1297-1300, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37088451
14.
The novel antipsychotic drug lurasidone enhances N-methyl-D-aspartate receptor-mediated synaptic responses.
Mol Pharmacol
; 81(2): 113-9, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22072817
15.
Cellular mechanisms for dopamine D4 receptor-induced homeostatic regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors.
J Biol Chem
; 286(28): 24957-65, 2011 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21622557
16.
Amyloid beta peptide-(1-42) induces internalization and degradation of beta2 adrenergic receptors in prefrontal cortical neurons.
J Biol Chem
; 286(36): 31852-63, 2011 Sep 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-21757762
17.
Impaired alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor trafficking and function by mutant huntingtin.
J Biol Chem
; 286(39): 33719-28, 2011 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-21832090
18.
Disrupted GABAAR trafficking and synaptic inhibition in a mouse model of Huntington's disease.
Neurobiol Dis
; 46(2): 497-502, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22402331
19.
Acute stress enhances glutamatergic transmission in prefrontal cortex and facilitates working memory.
Proc Natl Acad Sci U S A
; 106(33): 14075-9, 2009 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-19666502
20.
Ubiquitin-dependent lysosomal targeting of GABA(A) receptors regulates neuronal inhibition.
Proc Natl Acad Sci U S A
; 106(41): 17552-7, 2009 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-19815531