Detalhe da pesquisa
1.
Hypusination Maintains Intestinal Homeostasis and Prevents Colitis and Carcinogenesis by Enhancing Aldehyde Detoxification.
Gastroenterology
; 165(3): 656-669.e8, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37271289
2.
Dicarbonyl Electrophiles Mediate Inflammation-Induced Gastrointestinal Carcinogenesis.
Gastroenterology
; 160(4): 1256-1268.e9, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33189701
3.
Cyclooxygenase inhibition targets neurons to prevent early behavioural decline in Alzheimer's disease model mice.
Brain
; 139(Pt 7): 2063-81, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27190010
4.
Suppression of Alzheimer-associated inflammation by microglial prostaglandin-E2 EP4 receptor signaling.
J Neurosci
; 34(17): 5882-94, 2014 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-24760848
5.
Levuglandin forms adducts with histone h4 in a cyclooxygenase-2-dependent manner, altering its interaction with DNA.
Biochemistry
; 53(15): 2436-41, 2014 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24684440
6.
Protein modification by adenine propenal.
Chem Res Toxicol
; 27(10): 1732-42, 2014 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25211669
7.
Discovery of Protease-Activated Receptor 4 (PAR4)-Tethered Ligand Antagonists Using Ultralarge Virtual Screening.
ACS Pharmacol Transl Sci
; 7(4): 1086-1100, 2024 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38633591
8.
Antigenic mapping and functional characterization of human New World hantavirus neutralizing antibodies.
Elife
; 122023 03 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36971354
9.
Characterization of scavengers of gamma-ketoaldehydes that do not inhibit prostaglandin biosynthesis.
Chem Res Toxicol
; 23(1): 240-50, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20041722
10.
Mitochondrial Isolevuglandins Contribute to Vascular Oxidative Stress and Mitochondria-Targeted Scavenger of Isolevuglandins Reduces Mitochondrial Dysfunction and Hypertension.
Hypertension
; 76(6): 1980-1991, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33012204
11.
Scavenging of reactive dicarbonyls with 2-hydroxybenzylamine reduces atherosclerosis in hypercholesterolemic Ldlr-/- mice.
Nat Commun
; 11(1): 4084, 2020 08 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32796843
12.
Highly Reactive Isolevuglandins Promote Atrial Fibrillation Caused by Hypertension.
JACC Basic Transl Sci
; 5(6): 602-615, 2020 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-32613146
13.
Pyridine and pyrimidine analogs of acetaminophen as inhibitors of lipid peroxidation and cyclooxygenase and lipoxygenase catalysis.
Org Biomol Chem
; 7(24): 5103-12, 2009 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-20024105
14.
Pyridoxamine analogues scavenge lipid-derived gamma-ketoaldehydes and protect against H2O2-mediated cytotoxicity.
Biochemistry
; 45(51): 15756-67, 2006 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-17176098
15.
Cyclooxygenase-dependent lipid-modification of brain proteins.
Brain Pathol
; 15(2): 139-42, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15912886
16.
Gastroesophageal Reflux Induces Protein Adducts in the Esophagus.
Cell Mol Gastroenterol Hepatol
; 7(2): 480-482.e7, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30827415
17.
Rational Design of Novel Pyridinol-Fused Ring Acetaminophen Analogues.
ACS Med Chem Lett
; 4(8): 710-714, 2013 Aug 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24482730
18.
Determination of 3-methoxysalicylamine levels in mouse plasma and tissue by liquid chromatography-tandem mass spectrometry: application to in vivo pharmacokinetics studies.
J Chromatogr B Analyt Technol Biomed Life Sci
; 879(15-16): 1098-104, 2011 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21489890
19.
On-tissue chemical derivatization of 3-methoxysalicylamine for MALDI-imaging mass spectrometry.
J Mass Spectrom
; 46(8): 840-6, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21834023
20.
Determination of the Pharmacokinetics and Oral Bioavailability of Salicylamine, a Potent γ-Ketoaldehyde Scavenger, by LC/MS/MS.
Pharmaceutics
; 2(1): 18-29, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21822464