Detalhe da pesquisa
1.
Structures, functions and adaptations of the human LINE-1 ORF2 protein.
Nature
; 626(7997): 194-206, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38096902
2.
Production of a human neutralizing monoclonal antibody and its crystal structure in complex with ectodomain 3 of the interleukin-13 receptor α1.
Biochem J
; 451(2): 165-75, 2013 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23384096
3.
Evidence for cyclic diguanylate as a vaccine adjuvant with novel immunostimulatory activities.
Cell Immunol
; 278(1-2): 113-9, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23121983
4.
Identification of the lateral interaction surfaces of human histocompatibility leukocyte antigen (HLA)-DM with HLA-DR1 by formation of tethered complexes that present enhanced HLA-DM catalysis.
J Exp Med
; 196(2): 173-83, 2002 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12119342
5.
Pillars article: Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity. Cell. 1993. 72: 551-560.
J Immunol
; 190(7): 3018-27, 2013 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23526827
6.
Genetic ablation or pharmacological blockade of dipeptidyl peptidase IV does not impact T cell-dependent immune responses.
BMC Immunol
; 10: 19, 2009 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-19358731
7.
Disubstituted pyrimidines as Lck inhibitors.
Bioorg Med Chem Lett
; 19(18): 5440-3, 2009 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19674899
8.
TLR7 Protein Expression in Mild and Severe Lupus-Prone Models Is Regulated in a Leukocyte, Genetic, and IRAK4 Dependent Manner.
Front Immunol
; 10: 1546, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31354711
9.
Synthesis and biological activity of quinolinone and dihydroquinolinone p38 MAP kinase inhibitors.
Bioorg Med Chem Lett
; 18(6): 2222-6, 2008 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18316187
10.
Characterization of the NOD/scid-[Tg]DR1 mouse expressing HLA-DRB1*01 transgene: a model of SCID-hu mouse for vaccine development.
Exp Hematol
; 35(8): 1219-30, 2007 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17662890
11.
A human tissue-based functional assay platform to evaluate the immune function impact of small molecule inhibitors that target the immune system.
PLoS One
; 12(7): e0180870, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28719615
12.
Inhibition of spleen tyrosine kinase attenuates IgE-mediated airway contraction and mediator release in human precision cut lung slices.
Br J Pharmacol
; 173(21): 3080-3087, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27417329
13.
Pharmacological Inhibition of O-GlcNAcase Does Not Increase Sensitivity of Glucocorticoid Receptor-Mediated Transrepression.
PLoS One
; 10(12): e0145151, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26670328
14.
Hybrid-designed inhibitors of p38 MAP kinase utilizing N-arylpyridazinones.
J Med Chem
; 46(3): 349-52, 2003 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-12540232
15.
Novel N-arylpyrazolo[3,2-c]-based ligands for the glucocorticoid receptor: receptor binding and in vivo activity.
J Med Chem
; 47(10): 2441-52, 2004 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-15115388
16.
Specific stimulation of MHC-transgenic mouse T-cell hybridomas with xenogeneic APC.
Hum Immunol
; 64(2): 238-44, 2003 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-12559626
17.
FGF21 analogs of sustained action enabled by orthogonal biosynthesis demonstrate enhanced antidiabetic pharmacology in rodents.
Diabetes
; 61(2): 505-12, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22210323
18.
Chemical genetics define the roles of p38alpha and p38beta in acute and chronic inflammation.
J Biol Chem
; 282(48): 34663-71, 2007 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-17855341
19.
The discovery of a potent and selective lethal factor inhibitor for adjunct therapy of anthrax infection.
Bioorg Med Chem Lett
; 16(4): 964-8, 2006 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16338135
20.
p38 MAP kinase inhibitors: metabolically stabilized piperidine-substituted quinolinones and naphthyridinones.
Bioorg Med Chem Lett
; 16(1): 64-8, 2006 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16242322