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1.
Adv Exp Med Biol ; 1384: 43-61, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36217078

RESUMO

Obstructive sleep apnea (OSA) is a heterogeneous disease with many physiological implications. OSA is associated with a great diversity of diseases, with which it shares common and very often bidirectional pathophysiological mechanisms, leading to significantly negative implications on morbidity and mortality. In these patients, underdiagnosis of OSA is high. Concerning cardiorespiratory comorbidities, several studies have assessed the usefulness of simplified screening tests for OSA in patients with hypertension, COPD, heart failure, atrial fibrillation, stroke, morbid obesity, and in hospitalized elders.The key question is whether there is any benefit in the screening for the existence of OSA in patients with comorbidities. In this regard, there are few studies evaluating the performance of the various diagnostic procedures in patients at high risk for OSA. The purpose of this chapter is to review the existing literature about diagnosis in those diseases with a high risk for OSA, with special reference to artificial intelligence-related methods.


Assuntos
Fibrilação Atrial , Apneia Obstrutiva do Sono , Idoso , Inteligência Artificial , Fibrilação Atrial/complicações , Comorbidade , Humanos , Polissonografia/métodos , Apneia Obstrutiva do Sono/diagnóstico , Apneia Obstrutiva do Sono/epidemiologia
2.
Med Clin (Barc) ; 162(2): 49-55, 2024 01 26.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-37798245

RESUMO

INTRODUCTION: Obstructive sleep apnoea (OSA) and diabetes mellitus (DM) are very prevalent diseases frequently associated. Their coexistence is independently associated with an increased prevalence of cardiovascular comorbidities. As this association is underdiagnosed, it is necessary to optimise clinical suspicion by studying independent predictors of DM or prediabetes (preDM) in patients with OSA. METHOD: A simple randomised case-control study, matched for sex, body mass index (BMI) and age, aimed to study the association of OSA with DM and preDM and to identify independent predictors for both diseases in people with OSA. RESULTS: We included 208 cases with OSA and 208 controls without OSA. In the former, 18.8% had DM compared to only 10.1% in the latter (P=.00). Prevalence of preDM was 41.8% vs. 10.6%, respectively (P=.00). One hundred and twenty-four cases (59.6%) reported excessive daytime sleepiness (EDS) (Epworth scale, 10.5±3.1) vs. 24.5% of the control group (Epworth scale, 6.6±2.9). Apnoea-hypopnoea index (AHI) and O2 desaturation indices (IDO, CT90 and CT80) were significantly higher in the case group. The risk of MD was related to age, nocturnal hypoxaemia and EDS. The risk of pre-MD was related to BMI and AHI. CONCLUSIONS: OSA is associated with DM and preDM. Age, nocturnal hypoxaemia and EDS are predictors of DM. BMI and AHI are predictors of pre-MD.


Assuntos
Diabetes Mellitus , Estado Pré-Diabético , Apneia Obstrutiva do Sono , Humanos , Estudos de Casos e Controles , Apneia Obstrutiva do Sono/complicações , Apneia Obstrutiva do Sono/diagnóstico , Apneia Obstrutiva do Sono/epidemiologia , Diabetes Mellitus/epidemiologia , Comorbidade , Estado Pré-Diabético/epidemiologia , Hipóxia/epidemiologia
3.
Med Clin (Barc) ; 162(8): 363-369, 2024 04 26.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-38220552

RESUMO

INTRODUCTION: The association between obstructive sleep apnea (OSA) and glucose metabolism remains controversial. This study investigates the relationship between OSA and incident type 2 diabetes (DM) and prediabetes (preDM), as well as the effect of long-term CPAP (continuous positive airway pressure) treatment. METHODS: Follow-up study in a retrospective clinical cohort of patients with OSA and randomly selected controls. Data on incident DM and preDM as well as CPAP were obtained from hospital records. The relationship between baseline OSA and incident DM was examined using COX regression models. RESULTS: Three hundred and fifty-six patients, 169 with OSA and 187 controls were followed for a median of 98 months; 47 patients (13.2%) developed DM and 43 (12.1%) developed preDM. The 5-year cumulative incidence of DM was 10.7% (6.5-13.9%). 87% of subjects with preDM in the baseline sample progressed to incident DM. It is shown that body mass index (BMI), nocturnal hypoxia and apnea hypopnea index (AHI) are risk factors for the development of DM and that CPAP reduces this risk. CONCLUSIONS: Patients with OSA have a higher risk of developing DM. The risk factors involved are BMI, nocturnal hypoxia and AHI. Regular long-term CPAP use was associated with a decreased risk.


Assuntos
Diabetes Mellitus Tipo 2 , Estado Pré-Diabético , Apneia Obstrutiva do Sono , Humanos , Diabetes Mellitus Tipo 2/complicações , Diabetes Mellitus Tipo 2/epidemiologia , Estudos Retrospectivos , Seguimentos , Apneia Obstrutiva do Sono/complicações , Apneia Obstrutiva do Sono/epidemiologia , Apneia Obstrutiva do Sono/terapia , Pressão Positiva Contínua nas Vias Aéreas , Hipóxia
4.
Respir Med ; 222: 107514, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-38171405

RESUMO

INTRODUCTION: The quality of e-Consultations in the COPD is unknown. The objectives of this study were (i) to evaluate the quality of referrals; (ii) to define the characteristics of patients referred from Primary Care (PC) to the Unit of Pulmonology; and (iii) to describe differences between accepted and rejected patients. METHODS: A retrospective, observational study of e-Consultations requested by PC for suspected COPD throughout 2022. To quantify the quality of the e-Consultations, an arbitrary scale of 12 variables (score 0-10) was created. RESULTS: In total, 384 e-Consultations were reviewed, of which 167 (43.5 %) resulted in a face-to-face visit, and 217 (56.5 %) were rejected. No differences were observed between the two types of patients, except for confirmations of diagnostic suspicion of COPD [significantly higher in accepted patients (p = 0.042)]; physical examination data of rejected patients (more data provided; p = 0.015); and lung function (significantly better in rejected patients). The mean quality of referrals was acceptable (5.6 ± 2.1 score): 121 (31.3 %) had insufficient quality; 118 (30.5 %) acceptable; 75 (19.4 %) good, and 30 (7.8 %) excellent. Quality was low in half of the variables analyzed (6/12); acceptable in 3, and good in another 3. The capacity of resolution of referrals was good (one e-Consultation) in 199 requests (66.1 %); deficient (two e-Consultations) in 72 (23.9 %), and poor (≥3 e-Consultations) in 30 (10 %). Overdiagnosis was 40.2 % (86/214 e-Consultations). The risk could be classified in 247 patients (64.3 %; 135 low-risk; 90 high-risk). CONCLUSIONS: When adequate information is provided, e-Consultations help identify different levels of severity. However, the quality and capacity of resolution of referrals were suboptimal, with a high percentage of overdiagnoses.


Assuntos
Doença Pulmonar Obstrutiva Crônica , Humanos , Estudos Retrospectivos , Doença Pulmonar Obstrutiva Crônica/diagnóstico , Doença Pulmonar Obstrutiva Crônica/epidemiologia , Encaminhamento e Consulta
5.
Can Respir J ; 2022: 2423272, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36353446

RESUMO

Introduction: This study assesses the impact of an electronic physician-to-physician consultation program on the waiting list and the costs of a Pulmonology Unit. Materials and Methods: A prepost intervention study was conducted after a new ambulatory pulmonary care protocol was implemented and the capacity of the unit was adopted. In the new model, physicians at all levels of healthcare send electronic consultations to specialists. Results: In the preintervention year (2019), the Unit of Pulmonology attended 7,055 consultations (466 e-consultations and 6,589 first face-to-face visits), which decreased to 6,157 (3,934 e-consultations and 2,223 first face-to-face visits; 12.7% reduction) in the postintervention year (all were e-consultations). The mean wait time for the first appointment was 25.7 days in 2019 versus 3.2 days in 2021 (p < 0.001). In total, 43.5% of cases were solved via physician-to-physiciane-consultation. A total of 2,223 patients needed a face-to-face visit, with a mean wait time of 7.5 days. The mean of patients in the waiting listing decreased from 450.8 in 2019 to 44.8 in 2021 (90% reduction). The annual time devoted to e-consultations and first face-to-face visits following an e-consultation diminished significantly after the intervention (1,724 hours versus 2,312.8; 25.4% reduction). Each query solved via e-consultation represented a saving of €652.8, resulting in a total annual saving of €827,062. Conclusions: Physician-to-physiciane-consultations reduce waiting times, improve access of complex patients to specialty care, and ensure that cases are managed at the appropriate level. E-consultation reduces costs, which benefits both, society and the healthcare system.


Assuntos
Médicos , Pneumologia , Consulta Remota , Humanos , Consulta Remota/métodos , Análise Custo-Benefício , Pacientes Ambulatoriais , Encaminhamento e Consulta , Eletrônica
6.
Heart Lung ; 56: 62-69, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35780571

RESUMO

BACKGROUND: Sarcoidosis is a multiorgan granulomatous disease with a variable course. OOBJECTIVES: The purpose of this study is to identify the patients that are more likely to experience disease progression. METHODS: A retrospective study in patients ≥18 years. Pulmonary function and radiological stage (Scadding criteria) were assessed at diagnosis, and at 1, 3 and 5 years. Sarcoidosis progression was established based on deterioration of radiological or pulmonary function (decrease ≥10% of FVC and/or ≥15% of diffusing capacity of the lung (DLCO). RESULTS: The sample included 277 caucasian patients [mean age, 50±13.6; 69.7% between 31-60 years; 56.3% men]. In total, 65% had stage II sarcoidosis, whereas only 8.3% had stage III/IV disease. Mean pulmonary function (FVC, FEV1, FEV1/FVC and DLCO) at diagnosis was 103±21.8, 96±22.2, 76.2±8 and 81.7±21.7, respectively. The percentage of patients with normal FVC and DLCO was 72.2% and 51.8%, respectively. Radiological stage did not change significantly during follow-up (5 years; p=0.080) and only progressed in 13 patients (5.7%). At 3 years, FVC improved, whereas DLCO exacerbated significantly (p<0.001 for the two). Disease progressed in 34.5% of the patients (57/165) whose pulmonary function and radiological stage were available (both baseline and at 3 years). Age was associated with disease progression [OR=1.04 (95%CI=1.01, 1.06)]. Risk increased by 4% for each year older a patient was at diagnosis. CONCLUSIONS: At 3 years, a third of patients experienced sarcoidosis progression. Age was the only factor associated with disease prognosis.


Assuntos
Capacidade de Difusão Pulmonar , Sarcoidose , Masculino , Humanos , Adulto , Pessoa de Meia-Idade , Feminino , Estudos Retrospectivos , Testes de Função Respiratória , Pulmão , Progressão da Doença
7.
Med Clin (Barc) ; 157(3): 106-113, 2021 08 13.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-32829922

RESUMO

INTRODUCTION: Diabetes mellitus and sleep apnoea-hypopnoea syndrome appear to be related, but it is not well defined whether there is an increased risk of peripheral neuropathy in patients with both diseases. For this reason, we conducted a systematic review. METHODS: Bibliographic search in 3 electronic databases using a predefined strategy and the PRISMA methodology. Only original studies (any type of design) published from 2000 onwards in English, French, Portuguese or Spanish were included. A study quality scale was established. RESULTS: Twelve articles were selected, of which six studied type 2 diabetic patients. The overall prevalence of sleep apnoea-hypopnoea syndrome was 43.7% (1,559/3,564 patients). Diabetic neuropathy was more frequent in patients with sleep apnoea-hypopnoea syndrome in nine studies, although significantly only in four (60% vs 27%, P<.001; 64.5% vs 36%, P=.03; 37% vs 23.4%, P<.02; 66.6% vs 0%, P=.007). In one study, diabetic neuropathy was more frequent in patients without sleep apnoea-hypopnoea syndrome (although not statistically significant) and in 2 no comparison was made between patients with/without sleep apnoea/hypopnoea syndrome. CONCLUSIONS: The observed results suggest a relationship between diabetes mellitus and sleep apnoea-hypopnoea syndrome in the occurrence of diabetic neuropathy.


Assuntos
Diabetes Mellitus , Neuropatias Diabéticas , Apneia Obstrutiva do Sono , Neuropatias Diabéticas/epidemiologia , Humanos , Prevalência , Apneia Obstrutiva do Sono/complicações , Apneia Obstrutiva do Sono/diagnóstico , Apneia Obstrutiva do Sono/epidemiologia
8.
Arch Bronconeumol ; 57(10): 637-647, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-35702904

RESUMO

National health systems must ensure compliance with conditions such as equity, efficiency, quality, and transparency. Since it is the right of society to know the health outcomes of its healthcare system, our aim was to develop a proposal for the accreditation of respiratory medicine departments in terms of care, teaching, and research, measuring health outcomes using quality of care indicators. The management tools proposed in this article should be implemented to improve outcomes and help us achieve our objectives. Promoting accreditation can serve as a stimulus to improve clinical management and enable professionals to take on greater leadership roles and take action to improve outcomes in patient care.


Assuntos
Pneumologia , Acreditação , Departamentos Hospitalares , Humanos
9.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-33678474

RESUMO

National health systems must ensure compliance with conditions such as equity, efficiency, quality, and transparency. Since it is the right of society to know the health outcomes of its healthcare system, our aim was to develop a proposal for the accreditation of respiratory medicine departments in terms of care, teaching, and research, measuring health outcomes using quality of care indicators. The management tools proposed in this article should be implemented to improve outcomes and help us achieve our objectives. Promoting accreditation can serve as a stimulus to improve clinical management and enable professionals to take on greater leadership roles and take action to improve outcomes in patient care.

10.
Sleep Med ; 9(6): 660-6, 2008 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-17904420

RESUMO

BACKGROUND AND PURPOSE: Continuous positive airway pressure (CPAP) is an effective treatment for sleep apnea (SA), although the evidence for improving chronic heart failure (CHF) is inconclusive. Our aim was to evaluate the effect of CPAP treatment on the left ventricle ejection fraction (LVEF) among other cardiological variables in a randomized, multicenter, placebo (sham-CPAP)-controlled study. METHODS: After the selection procedure, 60 patients with CHF with LVEF<45% and SA with an apnea-hypopnea index (AHI)>10/h were evaluated at baseline, and after 3 months of treatment with optimal CPAP or sham-CPAP. The assessment was based on the LVEF, hypertension, daytime sleepiness (Epworth sleepiness scale [ESS]), quality of life (SF-36), New York Heart Scale (NYHA score), dyspnea (by using the Borg scale) and exercise tolerance (6-min walk test). RESULTS: The mean AHI was normalized in the optimal CPAP group but not in the sham-CPAP group. The LVEF showed a significant improvement in the group of patients treated with CPAP (2.5; 95% CI: 0.6 to 4.3), which was not observed in the sham-CPAP group (0.0; 95% CI: -2.1 to 2.1). However, the change in the LVEF from baseline to 3 months was not significantly greater in the whole group (obstructive and Cheyne-Stokes events) treated with CPAP than in the control group (p: 0.07). In patients with only obstructive sleep apnea (OSA), who account for 83% of the total population, there was a significant improvement in the LVEF in the group of patients treated with CPAP but no such improvement in the sham-CPAP group. In this OSA group, the change in the LVEF from baseline to 3 months was significantly greater in the group treated with CPAP than in the sham-CPAP group (p: 0.03). The other variables studied were not modified. When the patients were divided according to the severity of the LVEF (a LVEF cut-off of 30%), improvement was observed in those with a LVEF>30. No changes were found in the other cardiological variables. CONCLUSIONS: CPAP therapy proved to be useful in patients with associated sleep-disordered breathing and CHF. The improvement was more marked in patients with a LVEF>30%. However, the increased LVEF in the CPAP group was not accompanied by changes in the other cardiological variables.


Assuntos
Pressão Positiva Contínua nas Vias Aéreas , Insuficiência Cardíaca/fisiopatologia , Síndromes da Apneia do Sono/fisiopatologia , Síndromes da Apneia do Sono/terapia , Volume Sistólico/fisiologia , Idoso , Tolerância ao Exercício , Feminino , Insuficiência Cardíaca/complicações , Humanos , Masculino , Pessoa de Meia-Idade , Polissonografia , Qualidade de Vida , Síndromes da Apneia do Sono/complicações , Resultado do Tratamento
12.
Med Biol Eng Comput ; 46(4): 323-32, 2008 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-17968604

RESUMO

The aim of this study is to assess the ability of radial basis function (RBF) classifiers as an assistant tool for the diagnosis of the obstructive sleep apnoea syndrome (OSAS). A total of 187 subjects suspected of suffering from OSAS were available for our research. The initial population was divided into training, validation and test sets for deriving and testing our neural classifiers. We used nonlinear features from nocturnal oxygen saturation (SaO(2)) to perform patients' classification. We evaluated three different RBF construction techniques based on the following algorithms: k-means (KM), fuzzy c-means (FCM) and orthogonal least squares (OLS). A diagnostic accuracy of 86.1, 84.7 and 85.5% was provided by the networks developed with KM, FCM and OLS, respectively. The three proposed networks achieved an area under the receiver operating characteristic (ROC) curve over 0.90. Our results showed that a useful non-invasive method could be applied to diagnose OSAS from nonlinear features of SaO(2) with RBF classifiers.


Assuntos
Modelos Estatísticos , Redes Neurais de Computação , Reconhecimento Automatizado de Padrão , Apneia Obstrutiva do Sono/diagnóstico , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Oximetria , Oxigênio/sangue , Curva ROC , Sensibilidade e Especificidade
13.
Comput Methods Programs Biomed ; 92(1): 79-89, 2008 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-18672313

RESUMO

The aim of this study is to assess the ability of multilayer perceptron (MLP) neural networks as an assistant tool in the diagnosis of the obstructive sleep apnoea syndrome (OSAS). Non-linear features from nocturnal oxygen saturation (SaO(2)) recordings were used to discriminate between OSAS positive and negative patients. A total of 187 subjects suspected of suffering from OSAS (111 with a positive diagnosis of OSAS and 76 with a negative diagnosis of OSAS) took part in the study. The initial population was divided into training, validation and test sets for deriving and testing our neural network classifier. Three methods were applied to extract non-linear features from SaO(2) signals: approximate entropy (ApEn), central tendency measure (CTM) and Lempel-Ziv complexity (LZC). The selected MLP-based classifier provided a diagnostic accuracy of 85.5% (89.8% sensitivity and 79.4% specificity). Our neural network algorithm could represent a useful technique for OSAS detection. It could contribute to reduce the demand for polysomnographic studies in OSAS screening.


Assuntos
Diagnóstico por Computador/métodos , Redes Neurais de Computação , Oximetria/métodos , Reconhecimento Automatizado de Padrão/métodos , Polissonografia/métodos , Apneia Obstrutiva do Sono/diagnóstico , Algoritmos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Apneia Obstrutiva do Sono/fisiopatologia
14.
IEEE Trans Biomed Eng ; 54(1): 107-13, 2007 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-17260861

RESUMO

Approximate entropy (ApEn) is a family of statistics introduced as a quantification of regularity in time series without any a priori knowledge about the system generating them. The aim of this preliminary study was to assess whether a time series analysis of arterial oxygen saturation (SaO2) signals from overnight pulse oximetry by means of ApEn could yield essential information on the diagnosis of obstructive sleep apnea (OSA) syndrome. We analyzed SaO2 signals from 187 subjects: 111 with a positive diagnosis of OSA and 76 with a negative diagnosis of OSA. We divided our data in a training set (44 patients with OSA Positive and 30 patients with OSA Negative) and a test set (67 patients with OSA Positive and 46 patients with OSA Negative). The training set was used for algorithm development and optimum threshold selection. Results showed that recurrence of apnea events in patients with OSA determined a significant increase in ApEn values. This method was assessed prospectively using the test dataset, where we obtained 82.09% sensitivity and 86.96% specificity. We conclude that ApEn analysis of SaO2 from pulse oximetric recording could be useful in the study of OSA.


Assuntos
Algoritmos , Diagnóstico por Computador/métodos , Monitorização Fisiológica/métodos , Oximetria/métodos , Apneia Obstrutiva do Sono/diagnóstico , Inteligência Artificial , Entropia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Reconhecimento Automatizado de Padrão/métodos , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
15.
Artif Intell Med ; 41(1): 13-24, 2007 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-17643971

RESUMO

OBJECTIVES: Nocturnal pulse oximetry is a widely used alternative to polysomnography (PSG) in screening for obstructive sleep apnea (OSA) syndrome. Several oximetric indexes have been derived from nocturnal blood oxygen saturation (SaO2). However, they suffer from several limitations. The present study is focused on the usefulness of nonlinear methods in deriving new measures from oximetry signals to improve the diagnostic accuracy of classical oximetric indexes. Specifically, we assessed the validity of central tendency measure (CTM) as a screening test for OSA in patients clinically suspected of suffering from this disease. MATERIALS AND METHODS: We studied 187 subjects suspected of suffering from OSA referred to the sleep unit. A nocturnal pulse oximetry study was applied simultaneously to a conventional PSG. Three different index groups were compared. The first one was composed by classical indexes provided by our oximeter: oxygen desaturation indexes (ODIs) and cumulative time spent below a saturation of 90% (CT90). The second one was formed by indexes derived from a nonlinear method previously studied by our group: approximate entropy (ApEn). The last one was composed by indexes derived from a CTM analysis. RESULTS: For a radius in the scatter plot equal to 1, CTM values corresponding to OSA positive patients (0.30+/-0.20, mean+/-S.D.) were significantly lower (p<<0.001) than those values from OSA negative subjects (0.71+/-0.18, mean+/-S.D.). CTM was significantly correlated with classical indexes and indexes from ApEn analysis. CTM provided the highest correlation with the apnea-hipopnea index AHI (r=-0.74, p<0.0001). Moreover, it reached the best results from the receiver operating characteristics (ROC) curve analysis, with 90.1% sensitivity, 82.9% specificity, 88.5% positive predictive value, 85.1% negative predictive value, 87.2% accuracy and an area under the ROC curve of 0.924. Finally, the AHI derived from the quadratic regression curve for the CTM showed better agreement with the AHI from PSG than classical and ApEn derived indexes. CONCLUSION: The results suggest that CTM could improve the diagnostic ability of SaO2 signals recorded from portable monitoring. CTM could be a useful tool for physicians in the diagnosis of OSA syndrome.


Assuntos
Oximetria/métodos , Oxigênio/sangue , Processamento de Sinais Assistido por Computador , Apneia Obstrutiva do Sono/sangue , Apneia Obstrutiva do Sono/diagnóstico , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Variações Dependentes do Observador , Polissonografia , Valor Preditivo dos Testes , Reprodutibilidade dos Testes
17.
Respir Med ; 100(6): 1020-7, 2006 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-16289589

RESUMO

UNLABELLED: The aim of this study was to identify associations between performance on driving simulators, subject sleep complaints, and risk of traffic accidents in a population undergoing OSAS investigation. PATIENTS AND METHODS: One hundred and twenty-nine consecutive adult patients with a driver's licence and clinical symptoms of OSA were initially recruited from the hospital waiting list. Each patient was applied a polysomnography and two driving tests. Patients also completed a Basic Nordic Sleep Questionnaire, Epworth Sleepiness Scale and SF-36 quality of life questionnaire. RESULTS: Poor performance in vigilance was associated with alcohol intake (OR 4.41, 95% CI 1.13-17.20, P<0.05), and SF-36 vitality dimension (OR 0.97, 95% CI 0.94-0.99, P<0.05). Poor tracking error was associated with female gender (OR 6.79, 95% CI 1.37-33.65, P<0.05), alcohol intake (OR 3.32, 95% CI 1.03-10.63, P<0.05), and a history of accidents in the previous year (OR 5.84, 95% CI 1.33-25.68, P<0.05). Poor reaction time was only associated with age (OR 1.12, 95% CI 1.03-1.21, P<0.01). When all three performance measures were studied jointly, only reaction time was associated with self-reported dozing while driving (OR 5.39, 95% CI 1.10-26.32, P<0.05), and irresistible tendency to fall asleep was associated with poor tracking error (P<0.05). CONCLUSIONS: Performance on driving simulators is associated with some sleep complaints in OSA patients. Although these measures are not directly associated to traffic accidents, they are, in fact, associated to related circumstances such as dozing while driving and falling asleep while driving.


Assuntos
Acidentes de Trânsito , Nível de Alerta , Atenção , Condução de Veículo , Apneia Obstrutiva do Sono/psicologia , Adulto , Fatores Etários , Consumo de Bebidas Alcoólicas , Estudos de Casos e Controles , Distribuição de Qui-Quadrado , Simulação por Computador , Feminino , Nível de Saúde , Humanos , Modelos Logísticos , Masculino , Polissonografia , Tempo de Reação , Risco , Fatores Sexuais
18.
Artif Intell Med ; 37(2): 111-8, 2006 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-16386411

RESUMO

OBJECTIVE: The present study assessed the validity of approximate entropy (ApEn) analysis of arterial oxygen saturation (SaO(2)) data obtained from pulse oximetric recordings as a diagnostic test for obstructive sleep apnea (OSA) in patients clinically suspected of suffering this disease. METHODOLOGY: A sample of 187 referred outpatients, clinically suspected of having OSA, was studied using nocturnal pulse oximetric recording performed simultaneously with complete polysomnography. ApEn analysis was applied to SaO(2) data. RESULTS: Patients with OSA presented significantly higher approximate entropy levels than those without OSA (1.08+/-0.30 versus 0.47+/-0.26). Apnea-hypopnea index was correlated significantly with ApEn (r=0.607; p<0.001). Using receiver operating characteristic curve analysis, we obtained a diagnostic sensitivity of 88.3% and specificity of 82.9%, positive predictive value of 88.3% and a negative predictive value of 82.9%, at a threshold of 0.679. As a diagnostic test, this method presents high sensitivity and specificity compared to traditional methods in the diagnosis of OSA. CONCLUSION: We conclude that ApEn analysis of SaO(2) data obtained from pulse oximetric recordings could be useful as a diagnostic technique for OSA subjects.


Assuntos
Oxigênio/sangue , Apneia Obstrutiva do Sono/sangue , Apneia Obstrutiva do Sono/diagnóstico , Adulto , Idoso , Idoso de 80 Anos ou mais , Inteligência Artificial , Monitorização Transcutânea dos Gases Sanguíneos/estatística & dados numéricos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Polissonografia , Doença Pulmonar Obstrutiva Crônica/sangue , Doença Pulmonar Obstrutiva Crônica/complicações , Doença Pulmonar Obstrutiva Crônica/diagnóstico , Curva ROC , Apneia Obstrutiva do Sono/complicações
19.
Med. clín (Ed. impr.) ; 157(3): 106-113, agosto 2021. tab
Artigo em Espanhol | IBECS (Espanha) | ID: ibc-211411

RESUMO

Introducción: La diabetes mellitus y el síndrome de apnea-hipopnea del sueño parecen estar relacionados, pero no está bien definido si en los pacientes con ambas enfermedades existe un mayor riesgo de neuropatía periférica. Para ello, realizamos una revisión sistemática.MétodosBúsqueda bibliográfica en 3 bases de datos electrónicas usando una estrategia predefinida y la metodología PRISMA. Solamente se incluyeron estudios originales (cualquier tipo de diseño) y publicados a partir del año 2000 en inglés, francés, portugués o español. Se estableció una escala de calidad de los estudios.ResultadosSe seleccionaron 12 artículos, de los que 6 estudiaban pacientes diabéticos tipo 2. La prevalencia global de síndrome de apnea-hipopnea del sueño fue del 43,7% (1.559/3.564 pacientes). La neuropatía diabética fue más frecuente en los pacientes con síndrome de apnea-hipopnea del sueño en 9 estudios, aunque solo en 4 de manera significativa (60 vs. 27%, p<0,001; 64,5 vs. 36%, p=0,03; 37 vs. 23,4%, p<0,02; 66,6 vs. 0%, p=0,007). En un estudio, la neuropatía diabética fue más frecuente en los pacientes sin síndrome de apnea-hipopnea del sueño (aunque sin significación estadística) y en 2 no se hizo la comparación entre pacientes con/sin síndrome de apnea-hipopnea del sueño.ConclusionesLos resultados observados indican una relación entre diabetes mellitus y síndrome de apnea-hipopnea del sueño en la aparición de neuropatía diabética.


Introduction: Diabetes mellitus and sleep apnoea-hypopnoea syndrome appear to be related, but it is not well defined whether there is an increased risk of peripheral neuropathy in patients with both diseases. For this reason, we conducted a systematic review.MethodsBibliographic search in 3 electronic databases using a predefined strategy and the PRISMA methodology. Only original studies (any type of design) published from 2000 onwards in English, French, Portuguese or Spanish were included. A study quality scale was established.ResultsTwelve articles were selected, of which six studied type 2 diabetic patients. The overall prevalence of sleep apnoea-hypopnoea syndrome was 43.7% (1,559/3,564 patients). Diabetic neuropathy was more frequent in patients with sleep apnoea-hypopnoea syndrome in nine studies, although significantly only in four (60% vs 27%, P<.001; 64.5% vs 36%, P=.03; 37% vs 23.4%, P<.02; 66.6% vs 0%, P=.007). In one study, diabetic neuropathy was more frequent in patients without sleep apnoea-hypopnoea syndrome (although not statistically significant) and in 2 no comparison was made between patients with/without sleep apnoea/hypopnoea syndrome.ConclusionsThe observed results suggest a relationship between diabetes mellitus and sleep apnoea-hypopnoea syndrome in the occurrence of diabetic neuropathy. (AU)


Assuntos
Humanos , Diabetes Mellitus , Neuropatias Diabéticas/epidemiologia , Apneia Obstrutiva do Sono/complicações , Apneia Obstrutiva do Sono/diagnóstico , Apneia Obstrutiva do Sono/epidemiologia
20.
Arch. bronconeumol. (Ed. impr.) ; 57(10): 637-647, Oct. 2021. ilus, tab
Artigo em Inglês | IBECS (Espanha) | ID: ibc-212172

RESUMO

National health systems must ensure compliance with conditions such as equity, efficiency, quality, and transparency. Since it is the right of society to know the health outcomes of its healthcare system, our aim was to develop a proposal for the accreditation of respiratory medicine departments in terms of care, teaching, and research, measuring health outcomes using quality of care indicators. The management tools proposed in this article should be implemented to improve outcomes and help us achieve our objectives. Promoting accreditation can serve as a stimulus to improve clinical management and enable professionals to take on greater leadership roles and take action to improve outcomes in patient care. (AU)


Los sistemas nacionales de salud deben garantizar a los ciudadanos el cumplimiento de unas condiciones básicas como la equidad, la eficiencia, la calidad y la transparencia. En aras del derecho que tiene la sociedad a conocer los resultados de salud de su área sanitaria, el objetivo de este artículo es elaborar una propuesta de acreditación de los servicios de neumología desde el punto de vista asistencial, docente e investigador, midiendo sus resultados de salud a través de indicadores de calidad en la atención. Para mejorar estos, deberíamos utilizar unas herramientas de gestión (que se desarrollan en el artículo) y que, sin duda, nos ayudarían a conseguir los objetivos propuestos. La mejora del nivel de acreditación puede servir como estímulo para perfeccionar la gestión clínica y para que los profesionales ejerzan una capacidad de dirección cada vez mayor y adopten medidas para reforzar los resultados en la atención a sus pacientes. (AU)


Assuntos
Humanos , Pneumologia , Sistemas de Saúde , Acreditação , Pneumopatias , Avaliação de Resultados em Cuidados de Saúde , Espanha
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