Detalhe da pesquisa
1.
A phase 1/2 study of pepinemab in children, adolescents, or young adults with recurrent or refractory solid tumors: A children's oncology group consortium report (ADVL1614).
Pediatr Blood Cancer
; 71(6): e30938, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38520670
2.
Semaphorin 4D is upregulated in neurons of diseased brains and triggers astrocyte reactivity.
J Neuroinflammation
; 19(1): 200, 2022 Aug 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35933420
3.
Anti-Semaphorin 4D Rescues Motor, Cognitive, and Respiratory Phenotypes in a Rett Syndrome Mouse Model.
Int J Mol Sci
; 22(17)2021 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-34502373
4.
Photoactivable Glycolipid Antigens Generate Stable Conjugates with CD1d for Invariant Natural Killer T Cell Activation.
Bioconjug Chem
; 29(9): 3161-3173, 2018 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30085659
5.
Anti-semaphorin 4D immunotherapy ameliorates neuropathology and some cognitive impairment in the YAC128 mouse model of Huntington disease.
Neurobiol Dis
; 76: 46-56, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25662335
6.
SEMA4D compromises blood-brain barrier, activates microglia, and inhibits remyelination in neurodegenerative disease.
Neurobiol Dis
; 73: 254-68, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25461192
7.
CXCL13 antibody for the treatment of autoimmune disorders.
BMC Immunol
; 16: 6, 2015 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25879435
8.
CD1d-antibody fusion proteins target iNKT cells to the tumor and trigger long-term therapeutic responses.
Cancer Immunol Immunother
; 62(4): 747-60, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23242316
9.
A Vaccinia-based system for directed evolution of GPCRs in mammalian cells.
Nat Commun
; 14(1): 1770, 2023 03 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36997531
10.
Use of poxvirus display to select antibodies specific for complex membrane antigens.
MAbs
; 15(1): 2249947, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37635331
11.
Pepinemab antibody blockade of SEMA4D in early Huntington's disease: a randomized, placebo-controlled, phase 2 trial.
Nat Med
; 28(10): 2183-2193, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35941373
12.
A biological classification of Huntington's disease: the Integrated Staging System.
Lancet Neurol
; 21(7): 632-644, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35716693
13.
Sustained activation and tumor targeting of NKT cells using a CD1d-anti-HER2-scFv fusion protein induce antitumor effects in mice.
J Clin Invest
; 118(3): 994-1005, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18259610
14.
A Phase Ib/II Study of Pepinemab in Combination with Avelumab in Advanced Non-Small Cell Lung Cancer.
Clin Cancer Res
; 27(13): 3630-3640, 2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33820783
15.
Serial Stimulation of Invariant Natural Killer T Cells with Covalently Stabilized Bispecific T-cell Engagers Generates Antitumor Immunity While Avoiding Anergy.
Cancer Res
; 81(7): 1788-1801, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33483371
16.
Enhancing the antitumor functions of invariant natural killer T cells using a soluble CD1d-CD19 fusion protein.
Blood Adv
; 3(5): 813-824, 2019 03 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30858151
17.
Semaphorin4D Inhibition Improves Response to Immune-Checkpoint Blockade via Attenuation of MDSC Recruitment and Function.
Cancer Immunol Res
; 7(2): 282-291, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30514791
18.
Maximizing immune responses: the effects of covalent peptide linkage to beta-2-microglobulin.
Oncol Res
; 17(5): 205-16, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18980017
19.
Conclusions of the SIGNAL study in Huntington and implications for treatment of other slowly progressive neurodegenerative diseases.
Clin Transl Med
; 13(2): e1169, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36710564
20.
In vitro generation of tumor specific T cells that recognize a shared antigen of AML: molecular characterization of TCR genes.
Leuk Res
; 31(2): 195-202, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16750565