Detalhe da pesquisa
1.
Spectrum and prognostic relevance of driver gene mutations in acute myeloid leukemia.
Blood
; 128(5): 686-98, 2016 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27288520
2.
Acute myeloid leukemia with del(9q) is characterized by frequent mutations of NPM1, DNMT3A, WT1 and low expression of TLE4.
Genes Chromosomes Cancer
; 56(1): 75-86, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27636548
3.
Adults with Philadelphia chromosome-like acute lymphoblastic leukemia frequently have IGH-CRLF2 and JAK2 mutations, persistence of minimal residual disease and poor prognosis.
Haematologica
; 102(1): 130-138, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27561722
4.
Isolated trisomy 13 defines a homogeneous AML subgroup with high frequency of mutations in spliceosome genes and poor prognosis.
Blood
; 124(8): 1304-11, 2014 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24923295
5.
Exome sequencing identifies recurring FLT3 N676K mutations in core-binding factor leukemia.
Blood
; 122(10): 1761-9, 2013 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23878140
6.
Inactivation of TP53 correlates with disease progression and low miR-34a expression in previously treated chronic lymphocytic leukemia patients.
Blood
; 121(18): 3650-7, 2013 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-23525797
7.
The FLT3ITD mRNA level has a high prognostic impact in NPM1 mutated, but not in NPM1 unmutated, AML with a normal karyotype.
Blood
; 119(19): 4383-6, 2012 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22374696
8.
GATA2 zinc finger 1 mutations associated with biallelic CEBPA mutations define a unique genetic entity of acute myeloid leukemia.
Blood
; 120(2): 395-403, 2012 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-22649106
9.
Molecular response assessment by quantitative real-time polymerase chain reaction after induction therapy in NPM1-mutated patients identifies those at high risk of relapse.
Haematologica
; 99(8): 1317-25, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24816240
10.
Monitoring minimal residual disease in acute myeloid leukaemia with NPM1 mutations by quantitative PCR: clonal evolution is a limiting factor.
Br J Haematol
; 144(4): 517-23, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19055671
11.
Rapid and sensitive screening for CEBPA mutations in acute myeloid leukaemia.
Br J Haematol
; 143(2): 230-9, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18752591
12.
Persistence of pre-leukemic clones during first remission and risk of relapse in acute myeloid leukemia.
Leukemia
; 32(7): 1598-1608, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29472724
13.
Evolution of Cytogenetically Normal Acute Myeloid Leukemia During Therapy and Relapse: An Exome Sequencing Study of 50 Patients.
Clin Cancer Res
; 24(7): 1716-1726, 2018 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29330206
14.
The new and recurrent FLT3 juxtamembrane deletion mutation shows a dominant negative effect on the wild-type FLT3 receptor.
Sci Rep
; 6: 28032, 2016 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-27346558
15.
ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation.
Nat Commun
; 7: 11733, 2016 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27252013
16.
The NPM1 mutation type has no impact on survival in cytogenetically normal AML.
PLoS One
; 9(10): e109759, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25299584
17.
Combined molecular and clinical prognostic index for relapse and survival in cytogenetically normal acute myeloid leukemia.
J Clin Oncol
; 32(15): 1586-94, 2014 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-24711548
18.
Acute myeloid leukemia with biallelic CEBPA gene mutations and normal karyotype represents a distinct genetic entity associated with a favorable clinical outcome.
J Clin Oncol
; 28(4): 570-7, 2010 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20038735