Detalhe da pesquisa
1.
A latent subset of human hematopoietic stem cells resists regenerative stress to preserve stemness.
Nat Immunol
; 22(6): 723-734, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33958784
2.
Identification and characterization of in vitro expanded hematopoietic stem cells.
EMBO Rep
; 23(10): e55502, 2022 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35971894
3.
Simultaneous inhibition of Sirtuin 3 and cholesterol homeostasis targets acute myeloid leukemia stem cells by perturbing fatty acid ß-oxidation and inducing lipotoxicity.
Haematologica
; 108(9): 2343-2357, 2023 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37021547
4.
Newsletter Fall 2020: Clinician Investigator Trainee Association of Canada (CITAC).
Clin Invest Med
; 43(3): E1-4, 2020 09 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32971578
5.
Burden of Common Complex Disease Variants in the Exomes of Two Healthy Centenarian Brothers.
Gerontology
; 62(1): 58-62, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26066993
6.
Precise single-cell transcriptomic mapping of normal and leukemic cell states reveals unconventional lineage priming in acute myeloid leukemia.
bioRxiv
; 2023 Dec 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38234771
7.
Single-cell chromatin accessibility profiling of acute myeloid leukemia reveals heterogeneous lineage composition upon therapy-resistance.
Commun Biol
; 6(1): 765, 2023 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37479893
8.
KDM6 demethylases integrate DNA repair gene regulation and loss of KDM6A sensitizes human acute myeloid leukemia to PARP and BCL2 inhibition.
Leukemia
; 37(4): 751-764, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36720973
9.
Transcriptomic classes of BCR-ABL1 lymphoblastic leukemia.
Nat Genet
; 55(7): 1186-1197, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37337105
10.
SINGLE CELL DISSECTION OF DEVELOPMENTAL ORIGINS AND TRANSCRIPTIONAL HETEROGENEITY IN B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA.
bioRxiv
; 2023 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38106088
11.
Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia.
Cancer Discov
; 13(8): 1922-1947, 2023 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37191437
12.
A cellular hierarchy framework for understanding heterogeneity and predicting drug response in acute myeloid leukemia.
Nat Med
; 28(6): 1212-1223, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35618837
13.
Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t(8;21) AML.
Cell Rep
; 38(10): 110481, 2022 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35263585
14.
TFEB-mediated endolysosomal activity controls human hematopoietic stem cell fate.
Cell Stem Cell
; 28(10): 1838-1850.e10, 2021 10 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34343492
15.
Sphingosine-1-phosphate receptor 3 potentiates inflammatory programs in normal and leukemia stem cells to promote differentiation.
Blood Cancer Discov
; 2(1): 32-53, 2021 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33458693
16.
Enhancer Hijacking Drives Oncogenic BCL11B Expression in Lineage-Ambiguous Stem Cell Leukemia.
Cancer Discov
; 11(11): 2846-2867, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34103329
17.
Fundamental trends within falling match rates: Insights from the past decade of Canadian residency matching data.
Can Med Educ J
; 11(3): e31-e42, 2020 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-32802225
18.
Integration of intra-sample contextual error modeling for improved detection of somatic mutations from deep sequencing.
Sci Adv
; 6(50)2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33298453
19.
Sphingolipid Modulation Activates Proteostasis Programs to Govern Human Hematopoietic Stem Cell Self-Renewal.
Cell Stem Cell
; 25(5): 639-653.e7, 2019 11 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31631013
20.
Somatic Mitochondrial DNA Mutations in Diffuse Large B-Cell Lymphoma.
Sci Rep
; 8(1): 3623, 2018 02 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29483551