Detalhe da pesquisa
1.
Virtual screening of novel mTOR inhibitors for the potential treatment of human colorectal cancer.
Bioorg Chem
; 140: 106781, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37597440
2.
DBU-Catalyzed Aerobic CDC Reaction of Thiophenols.
J Org Chem
; 87(24): 16492-16505, 2022 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36473149
3.
Cobalt-promoted synthesis of sulfurated oxindoles via radical annulation of N-arylacrylamides with disulfides.
Org Biomol Chem
; 20(32): 6423-6431, 2022 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35880643
4.
Iron-Catalyzed Radical Annulation of Unsaturated Carboxylic Acids with Disulfides for the Synthesis of γ-Lactones.
J Org Chem
; 86(13): 8620-8629, 2021 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34097828
5.
Synthesis and biological evaluation of cajanonic acid A derivatives as potential PPARγ antagonists.
Bioorg Med Chem Lett
; 52: 128410, 2021 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34626784
6.
Minor immunosuppressive spiroorthoester group-containing pregnane glycosides from the root barks of Periploca sepium.
Bioorg Chem
; 108: 104641, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33517004
7.
Design, synthesis and evaluation of tetrahydrocarbazole derivatives as potential hypoglycemic agents.
Bioorg Chem
; 115: 105172, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34303898
8.
Novel berberine-based derivatives with potent hypoglycemic activity.
Bioorg Med Chem Lett
; 29(23): 126709, 2019 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31629632
9.
Pharmacokinetics, bioavailability and tissue distribution studies of rhodojaponin III in mice using QTRAP LC-MS/MS.
Biomed Chromatogr
; 33(11): e4649, 2019 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-31301694
10.
Subcellular drug distribution: mechanisms and roles in drug efficacy, toxicity, resistance, and targeted delivery.
Drug Metab Rev
; 50(4): 430-447, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30270675
11.
A Compositive Strategy to Study the Pharmacokinetics of TCMs: Taking Coptidis Rhizoma, and Coptidis Rhizoma-Glycyrrhizae Radix et Rhizoma as Examples.
Molecules
; 23(8)2018 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30111723
12.
[An Identification Study on Field-Derived Spectra of Grassland Combustibles and Soil Based on Fractal Theory].
Guang Pu Xue Yu Guang Pu Fen Xi
; 36(8): 2553-7, 2016 Aug.
Artigo
em Zh
| MEDLINE | ID: mdl-30074362
13.
Copper(ii)-catalyzed coupling reaction: an efficient and regioselective approach to N',N'-diaryl acylhydrazines.
Org Biomol Chem
; 13(7): 2055-63, 2015 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25518836
14.
Design, Synthesis, Formulation, and Bioevaluation of Trisubstituted Triazines as Highly Selective mTOR Inhibitors for the Treatment of Human Breast Cancer.
J Med Chem
; 67(9): 7330-7358, 2024 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38661655
15.
[Measurement and analysis of reflected information from crops canopy suffering from wind disaster influence].
Guang Pu Xue Yu Guang Pu Fen Xi
; 33(4): 1057-60, 2013 Apr.
Artigo
em Zh
| MEDLINE | ID: mdl-23841428
16.
[Multiple mechanisms of depression].
Sheng Li Ke Xue Jin Zhan
; 44(4): 253-8, 2013 Aug.
Artigo
em Zh
| MEDLINE | ID: mdl-24228515
17.
Identifying novel selective PPO inhibitors through structure-based virtual screening and bio-evaluation.
RSC Adv
; 13(16): 10873-10883, 2023 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37033434
18.
Design, synthesis and bioevaluation of PI3Kα-selective inhibitors as potential colorectal cancer drugs.
Eur J Med Chem
; 260: 115754, 2023 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37651880
19.
Targeting the PI3K/AKT/mTOR Signaling Pathway in the Treatment of Human Diseases: Current Status, Trends, and Solutions.
J Med Chem
; 65(24): 16033-16061, 2022 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36503229
20.
Computational study reveals substituted benzimidazole derivatives' binding selectivity to PI3Kδ and PI3Kγ.
J Mol Model
; 28(5): 123, 2022 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35438328