Detalhe da pesquisa
1.
Biomarkers of aging for the identification and evaluation of longevity interventions.
Cell
; 186(18): 3758-3775, 2023 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37657418
2.
Multiomic prediction of therapeutic targets for human diseases associated with protein phase separation.
Proc Natl Acad Sci U S A
; 120(40): e2300215120, 2023 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37774095
3.
PandaOmics: An AI-Driven Platform for Therapeutic Target and Biomarker Discovery.
J Chem Inf Model
; 2024 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38404138
4.
Discovery of 3-hydroxymethyl-azetidine derivatives as potent polymerase theta inhibitors.
Bioorg Med Chem
; 103: 117662, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38493730
5.
Discovery of novel MAT2A inhibitors by an allosteric site-compatible fragment growing approach.
Bioorg Med Chem
; 100: 117633, 2024 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38342078
6.
Discovery of macrocyclic CDK2/4/6 inhibitors with improved potency and DMPK properties through a highly efficient macrocyclic drug design platform.
Bioorg Chem
; 146: 107285, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38547721
7.
Skinly: A novel handheld IoT device for validating biophysical skin characteristics.
Skin Res Technol
; 30(3): e13613, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38419420
8.
Chemistry42: An AI-Driven Platform for Molecular Design and Optimization.
J Chem Inf Model
; 63(3): 695-701, 2023 02 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36728505
9.
Exploring the Advantages of Quantum Generative Adversarial Networks in Generative Chemistry.
J Chem Inf Model
; 63(11): 3307-3318, 2023 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37171372
10.
Discovery of novel and selective SIK2 inhibitors by the application of AlphaFold structures and generative models.
Bioorg Med Chem
; 91: 117414, 2023 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37467565
11.
Application of liquid biopsy as multi-functional biomarkers in head and neck cancer.
Br J Cancer
; 126(3): 361-370, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34876674
12.
COVIDomic: A multi-modal cloud-based platform for identification of risk factors associated with COVID-19 severity.
PLoS Comput Biol
; 17(7): e1009183, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34260589
13.
Fetal mitochondrial DNA in maternal plasma in surrogate pregnancies: Detection and topology.
Prenat Diagn
; 41(3): 368-375, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33140416
14.
Medicinal Chemists versus Machines Challenge: What Will It Take to Adopt and Advance Artificial Intelligence for Drug Discovery?
J Chem Inf Model
; 60(6): 2657-2659, 2020 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32469509
15.
Adversarial Threshold Neural Computer for Molecular de Novo Design.
Mol Pharm
; 15(10): 4386-4397, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29569445
16.
Entangled Conditional Adversarial Autoencoder for de Novo Drug Discovery.
Mol Pharm
; 15(10): 4398-4405, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30180591
17.
3D Molecular Representations Based on the Wave Transform for Convolutional Neural Networks.
Mol Pharm
; 15(10): 4378-4385, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29473756
18.
Reinforced Adversarial Neural Computer for de Novo Molecular Design.
J Chem Inf Model
; 58(6): 1194-1204, 2018 06 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29762023
19.
Aging Chart: a community resource for rapid exploratory pathway analysis of age-related processes.
Nucleic Acids Res
; 44(D1): D894-9, 2016 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26602690
20.
druGAN: An Advanced Generative Adversarial Autoencoder Model for de Novo Generation of New Molecules with Desired Molecular Properties in Silico.
Mol Pharm
; 14(9): 3098-3104, 2017 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28703000