Detalhe da pesquisa
1.
Phase separation in plants: New insights into cellular compartmentalization.
J Integr Plant Biol
; 63(11): 1835-1855, 2021 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-34314106
2.
Synthesis and biological evaluation of 7-methoxy-1-(3,4,5-trimethoxyphenyl)-4,5-dihydro-2H-benzo[e]indazoles as new colchicine site inhibitors.
Bioorg Med Chem Lett
; 29(18): 2632-2634, 2019 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31362922
3.
Design, synthesis, and bioactivity evaluation of novel Bcl-2/HDAC dual-target inhibitors for the treatment of multiple myeloma.
Bioorg Med Chem Lett
; 29(3): 349-352, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30594434
4.
Receptor-Like Kinase RUPO Interacts with Potassium Transporters to Regulate Pollen Tube Growth and Integrity in Rice.
PLoS Genet
; 12(7): e1006085, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27447945
5.
Corrigendum to 'Synthesis and biological evaluation of 7-methoxy-1-(3,4,5-trimethoxyphenyl)-4,5-dihydro-2H-benzo[e]indazoles as new colchicine site inhibitors' [Bioorgan. Med. Chem. Lett. 29 (2019) 2632-2634].
Bioorg Med Chem Lett
; 41: 128015, 2021 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33875347
6.
Structural modification of luteolin from Flos Chrysanthemi leads to increased tumor cell growth inhibitory activity.
Bioorg Med Chem Lett
; 26(15): 3464-7, 2016 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27353532
7.
Design, synthesis, and activity evaluation of selective inhibitors of anti-apoptotic Bcl-2 proteins: The effects on the selectivity of the P1 pockets in the active sites.
Bioorg Med Chem Lett
; 26(21): 5207-5211, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27712939
8.
Discovery of benzenesulfonamide derivatives as potent PI3K/mTOR dual inhibitors with in vivo efficacies against hepatocellular carcinoma.
Bioorg Med Chem
; 24(5): 957-66, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26819001
9.
Design, Synthesis and Biological Evaluation of 1,4-Disubstituted-3,4-dihydroisoquinoline Compounds as New Tubulin Polymerization Inhibitors.
Int J Mol Sci
; 16(5): 10173-84, 2015 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25950763
10.
Luteolin from Flos Chrysanthemi and its derivatives: New small molecule Bcl-2 protein inhibitors.
Bioorg Med Chem Lett
; 24(19): 4672-4677, 2014 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25193233
11.
Quantum chemistry calculation-aided discovery of potent small-molecule mimics of glutathione peroxidases for the treatment of cisplatin-induced hearing loss.
Eur J Med Chem
; 271: 116404, 2024 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38631262
12.
Synthesis and acrosin inhibitory activities of 5-phenyl-1H-pyrazole-3-carboxylic acid amide derivatives.
Bioorg Med Chem Lett
; 23(14): 4177-84, 2013 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23746472
13.
Discovery of 3,5-diaryl-1H-pyrazol-based ureas as potent RET inhibitors.
Eur J Med Chem
; 251: 115237, 2023 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36905915
14.
Discovery of Pyrrolo[2,3-c]pyridines as Potent and Reversible LSD1 Inhibitors.
ACS Med Chem Lett
; 14(10): 1389-1395, 2023 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37849536
15.
The DELLA-ABI4-HY5 module integrates light and gibberellin signals to regulate hypocotyl elongation.
Plant Commun
; 4(5): 100597, 2023 09 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37002603
16.
Design, synthesis, and activity evaluation of broad-spectrum small-molecule inhibitors of anti-apoptotic Bcl-2 family proteins: characteristics of broad-spectrum protein binding and its effects on anti-tumor activity.
Bioorg Med Chem Lett
; 22(1): 39-44, 2012 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22172701
17.
Synthesis and biological evaluation of 1-phenyl-1,2,3,4-dihydroisoquinoline compounds as tubulin polymerization inhibitors.
Arch Pharm (Weinheim)
; 345(6): 454-62, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22415658
18.
Synthesis and acrosin inhibitory activities of substituted ethyl 5-(4-aminophenyl)-1H-pyrazole-3-carboxylate derivatives.
Bioorg Med Chem Lett
; 21(19): 5822-5, 2011 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21880490
19.
Synthesis and acrosin inhibitory activity of substituted 4-amino-N-(diaminomethylene) benzenesulfonamide derivatives.
Bioorg Med Chem Lett
; 21(22): 6674-7, 2011 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21983437
20.
Discovery of novel human acrosin inhibitors by virtual screening.
J Comput Aided Mol Des
; 25(10): 977-85, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21984268