Detalhe da pesquisa
1.
Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism.
Cell
; 149(3): 656-70, 2012 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22541435
2.
ATRX loss induces telomere dysfunction and necessitates induction of alternative lengthening of telomeres during human cell immortalization.
EMBO J
; 38(19): e96659, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31454099
3.
SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression.
Nature
; 470(7333): 269-73, 2011 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-21289624
4.
From the Cover: Neutralization of terminal differentiation in gliomagenesis.
Proc Natl Acad Sci U S A
; 110(36): 14520-7, 2013 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-23918370
5.
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation.
Nature
; 455(7216): 1129-33, 2008 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-18948956
6.
Mig-6 controls EGFR trafficking and suppresses gliomagenesis.
Proc Natl Acad Sci U S A
; 107(15): 6912-7, 2010 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-20351267
7.
Histone demethylase KDM2A is a selective vulnerability of cancers relying on alternative telomere maintenance.
bioRxiv
; 2023 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36798426
8.
Histone demethylase KDM2A is a selective vulnerability of cancers relying on alternative telomere maintenance.
Nat Commun
; 14(1): 1756, 2023 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-36991019
9.
DAXX-ATRX regulation of p53 chromatin binding and DNA damage response.
Nat Commun
; 13(1): 5033, 2022 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36028493
10.
A FOXO1-dependent transcription network is a targetable vulnerability of mantle cell lymphomas.
J Clin Invest
; 132(24)2022 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36282572
11.
Mutant IDH Inhibits IFNγ-TET2 Signaling to Promote Immunoevasion and Tumor Maintenance in Cholangiocarcinoma.
Cancer Discov
; 12(3): 812-835, 2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34848557
12.
Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer.
Proc Natl Acad Sci U S A
; 105(49): 19372-7, 2008 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-19050074
13.
Cellular stress signaling activates type-I IFN response through FOXO3-regulated lamin posttranslational modification.
Nat Commun
; 12(1): 640, 2021 01 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33510167
14.
Therapy-Induced Transdifferentiation Promotes Glioma Growth Independent of EGFR Signaling.
Cancer Res
; 81(6): 1528-1539, 2021 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33509942
15.
CIC is a critical regulator of neuronal differentiation.
JCI Insight
; 5(9)2020 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32229723
16.
A Combination of BRD4 and HDAC3 Inhibitors Synergistically Suppresses Glioma Stem Cell Growth by Blocking GLI1/IL6/STAT3 Signaling Axis.
Mol Cancer Ther
; 19(12): 2542-2553, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32999044
17.
RGFP966, a histone deacetylase 3 inhibitor, promotes glioma stem cell differentiation by blocking TGF-ß signaling via SMAD7.
Biochem Pharmacol
; 180: 114118, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32585142
18.
Mature myelin maintenance requires Qki to coactivate PPARß-RXRα-mediated lipid metabolism.
J Clin Invest
; 130(5): 2220-2236, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32202512
19.
Next-generation whole exome sequencing of glioblastoma with a primitive neuronal component.
Brain Tumor Pathol
; 36(3): 129-134, 2019 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-30715630
20.
Bromodomain inhibitor jq1 induces cell cycle arrest and apoptosis of glioma stem cells through the VEGF/PI3K/AKT signaling pathway.
Int J Oncol
; 55(4): 879-895, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-31485609