Detalhe da pesquisa
1.
Engineering Hydroxylase Activity, Selectivity, and Stability for a Scalable Concise Synthesis of a Key Intermediate to Belzutifan.
Angew Chem Int Ed Engl
; 63(13): e202316133, 2024 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38279624
2.
Rapid Unambiguous Structure Elucidation of Streptnatamide A, a New Cyclic Peptide Isolated from A Marine-derived Streptomyces sp.
Chemistry
; 29(56): e202301813, 2023 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37452377
3.
Peptide Sequence Influence on the Differentiation of Valine and Norvaline by Hot Electron Capture Dissociation.
Anal Chem
; 91(7): 4381-4387, 2019 04 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30786210
4.
Differentiation of Norvaline and Valine in Peptides by Hot Electron Capture Dissociation.
Anal Chem
; 88(11): 5914-9, 2016 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27153319
5.
Determination of low levels of 2H-labeling using high-resolution mass spectrometry: application in studies of lipid flux and beyond.
Rapid Commun Mass Spectrom
; 28(3): 239-44, 2014 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24375874
6.
Characterization of a low-level unknown isomeric degradation product using an integrated online-offline top-down tandem mass spectrometry platform.
Anal Chem
; 85(19): 8964-7, 2013 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24003984
7.
Determination of ultra-trace metal-protein interactions in co-formulated monoclonal antibody drug product by SEC-ICP-MS.
MAbs
; 15(1): 2199466, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37032437
8.
Implementation of electron-induced dissociation mass spectrometry technique for differentiation of isomeric metabolites of diclofenac.
Rapid Commun Mass Spectrom
; 31(17): 1471-1475, 2017 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28621444
9.
Characterization of an unusual ring-contraction degradant of the antifungal agent posaconazole.
Magn Reson Chem
; 50(8): 576-9, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22715068
10.
Direct visualization of the drug release process of non-conductive polymeric implants via molecular imaging.
Anal Chim Acta
; 1230: 340395, 2022 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36192066
11.
Mass spectrometry imaging of diclofenac and its metabolites in tissues using nanospray desorption electrospray ionization.
Anal Chim Acta
; 1233: 340490, 2022 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36283780
12.
An Investigation of Instability in Dried Blood Spot Samples for Pharmacokinetic Sampling in Phase 3 Trials of Verubecestat.
AAPS J
; 24(3): 52, 2022 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35384529
13.
A chemoenzymatic strategy for site-selective functionalization of native peptides and proteins.
Science
; 376(6599): 1321-1327, 2022 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35709255
14.
Development of ProTx-II Analogues as Highly Selective Peptide Blockers of Nav1.7 for the Treatment of Pain.
J Med Chem
; 65(1): 485-496, 2022 01 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34931831
15.
Discovery of amide replacements that improve activity and metabolic stability of a bis-amide smoothened antagonist hit.
Bioorg Med Chem Lett
; 21(18): 5206-9, 2011 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21840217
16.
Determination of modification sites and relative quantitation in large protein conjugation via automated data processing.
J Pharm Biomed Anal
; 198: 113995, 2021 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33706146
17.
Design and Study of PEG Linkers That Enable Robust Characterization of PEGylated Proteins.
ACS Pharmacol Transl Sci
; 4(4): 1280-1286, 2021 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34423265
18.
Simultaneous multielement imaging of liver tissue using laser ablation inductively coupled plasma mass spectrometry.
Talanta
; 235: 122725, 2021 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34517593
19.
Immunotherapy combinations overcome resistance to bispecific T cell engager treatment in T cell-cold solid tumors.
Sci Transl Med
; 13(608)2021 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34433637
20.
Design of 1-piperazinyl-4-arylphthalazines as potent Smoothened antagonists.
Bioorg Med Chem Lett
; 20(12): 3618-22, 2010 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20493695