Research progress on live attenuated vaccine against African swine fever virus.

African swine fever (ASF) is an acute, hemorrhagic and severe infectious disease caused by African swine fever virus (ASFV) in domestic pigs and various wild boars, with a mortality rate up to 100%. ASF was first discovered in 1921 in Kenya. ASFV has a large genome and complex immune escape mechanism creating difficulties in the production of vaccines. Recently, remarkable advances have been made in vaccine development all over the world especially in live-attenuated vaccine. This article aims to review the research progress of ASF attenuated live vaccines in order to provide a reference for the development of vaccines for this disease.

Coagulation performance and mechanism of different novel covalently bonded organic silicon-aluminum/iron composite coagulant for As(V) removal from water: The role of hydrolysate species and the effect of coexisting microplastics.

Arsenate [As(V)] pollution is a challenge for water treatment, and the effect of coexisting microplastics (MPs) on As(V) removal is still not clear. In this study, series novel covalently bonded organic silicon-aluminum/iron composite coagulants (CSA/F) with different Al/Fe molar ratios were prepared for enhancing As(V) removal. The effect mechanism of MPs (PS MPs and PS-COOH MPs) on As(V) removal by using CSAF coagulation was analyzed. CSAF and CSF showed significantly better As(V) removal performance than other coagulants under the same conditions, especially CSF, more than 90 % As(V) removal was achieved at dosage of 20 mg/L and pH of 4.0-8.0. Interestingly, the introduction of silane coupling agent and the increase of Fe content in CSA/F changed the Al/Fe species distribution. Charge neutralization dominant in As(V) removal by using CSA, whereas adsorption and net sweeping contributed to As(V) coagulation by using CSAF and CSF with higher iron proportion at neutral pH. 3 µm MPs were removed by net sweeping of amorphous Al/Fe hydroxides, while 26 µm MPs were charge-neutralized or surface adsorbed by coagulant hydrolysates. The aliphatic C-H and -COOH functional groups of MPs were the main sites of hydrogen bonding adsorption with the hydroxyl groups of coagulant hydrolysates. This study is conducive to mitigating the environmental toxicity of arsenic and provides new insights into the interaction mechanism between composite pollutants and coagulants in waters.