Detalhe da pesquisa
1.
Pharmacological characterization of the small molecule 03A10 as an inhibitor of α-synuclein aggregation for Parkinson's disease treatment.
Acta Pharmacol Sin
; 44(6): 1122-1134, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-36627343
2.
Distal mutation V486M disrupts the catalytic activity of DPP4 by affecting the flap of the propeller domain.
Acta Pharmacol Sin
; 43(8): 2147-2155, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-34907358
3.
Competitive CatSper Activators of Progesterone from Rhynchosia volubilis.
Planta Med
; 88(11): 881-890, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-34359084
4.
DCZ5248, a novel dual inhibitor of Hsp90 and autophagy, exerts antitumor activity against colon cancer.
Acta Pharmacol Sin
; 42(1): 132-141, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-32404982
5.
[A new hexenol glycoside from Buddleja officinalis].
Zhongguo Zhong Yao Za Zhi
; 46(23): 6178-6184, 2021 Dec.
Artigo
em Zh
| MEDLINE | ID: mdl-34951244
6.
Author Correction: DCZ5248, a novel dual inhibitor of Hsp90 and autophagy, exerts antitumor activity against colon cancer.
Acta Pharmacol Sin
; 45(3): 660, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38012293
7.
Different structures of berberine and five other protoberberine alkaloids that affect P-glycoprotein-mediated efflux capacity.
Acta Pharmacol Sin
; 40(1): 133-142, 2019 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-30442987
8.
Computational insights into the G-protein-biased activation and inactivation mechanisms of the µ opioid receptor.
Acta Pharmacol Sin
; 39(1): 154-164, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-29188799
9.
Computational insights into the subtype selectivity and "message-address-efficacy" mechanisms of opioid receptors through JDTic binding and unbinding.
Acta Pharmacol Sin
; 39(3): 482-491, 2018 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-29047460
10.
Further New Diterpenoids as PTP1B Inhibitors from the Xisha Soft Coral Sinularia polydactyla.
Mar Drugs
; 16(4)2018 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29587405
11.
Luteolin-7-diglucuronide attenuates isoproterenol-induced myocardial injury and fibrosis in mice.
Acta Pharmacol Sin
; 38(3): 331-341, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-28112175
12.
Advances in the study of berberine and its derivatives: a focus on anti-inflammatory and anti-tumor effects in the digestive system.
Acta Pharmacol Sin
; 38(2): 157-167, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-27917872
13.
Docking-based structural splicing and reassembly strategy to develop novel deazapurine derivatives as potent B-RafV600E inhibitors.
Acta Pharmacol Sin
; 38(7): 1059-1068, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28414204
14.
Deciphering the pharmacological mechanism of the Chinese formula huanglian-jie-du decoction in the treatment of ischemic stroke using a systems biology-based strategy.
Acta Pharmacol Sin
; 36(6): 724-33, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25937634
15.
Inhibitory Effects of (2'R)-2',3'-dihydro-2'-(1-hydroxy-1-methylethyl)-2,6'-bibenzofuran-6,4'-diol on Mushroom Tyrosinase and Melanogenesis in B16-F10 Melanoma Cells.
Phytother Res
; 29(7): 1040-5, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25826437
16.
Novel Bayesian classification models for predicting compounds blocking hERG potassium channels.
Acta Pharmacol Sin
; 35(8): 1093-102, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24976154
17.
Multi-algorithm and multi-model based drug target prediction and web server.
Acta Pharmacol Sin
; 35(3): 419-31, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24487966
18.
Two new sulfated sesquiterpenoids from Petasites tricholobus.
Yao Xue Xue Bao
; 49(10): 1433-7, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25577874
19.
(M)- and (P)-bicelaphanol A, dimeric trinorditerpenes with promising neuroprotective activity from Celastrus orbiculatus.
J Nat Prod
; 76(4): 745-9, 2013 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-23421714
20.
Benzbromarone, an old uricosuric drug, inhibits human fatty acid binding protein 4 in vitro and lowers the blood glucose level in db/db mice.
Acta Pharmacol Sin
; 34(11): 1397-402, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24077632