Detalhe da pesquisa
1.
Targeting EFHD2 Inhibits Interferon-γ Signaling and Ameliorates Non-Alcoholic Steatohepatitis.
J Hepatol
; 2024 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38670321
2.
Design, synthesis and anti-necroptosis activity of fused heterocyclic MLKL inhibitors.
Bioorg Med Chem
; 102: 117659, 2024 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38442525
3.
Discovery of novel biaryl benzoxazepinones as dual-mode receptor-interacting protein kinase-1 (RIPK1) inhibitors.
Bioorg Med Chem
; 100: 117611, 2024 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38309200
4.
Pharmacokinetic, Tissue Distribution, Metabolite, and Toxicity Evaluation of the Matrine Derivative, (6aS, 10S, 11aR, 11bR, 11cS)-10-Methylaminododecahydro-3a, 7a-Diaza-benzo (de) Anthracene-8-thione.
Molecules
; 29(2)2024 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38257210
5.
Profiling of small-molecule necroptosis inhibitors based on the subpockets of kinase-ligand interactions.
Med Res Rev
; 43(6): 1974-2024, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37119044
6.
Discovery of marine phidianidine-based Nrf2 activators and their potential against oxLDL- and HG-induced injury in HUVECs.
Bioorg Med Chem Lett
; 95: 129468, 2023 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37689216
7.
Structure optimization of an F-indole-chalcone (FC116) on 4-methoxyphenyl group and therapeutic potential against colorectal cancers with low cytotoxicity.
Bioorg Chem
; 135: 106531, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37043882
8.
Analysis on benzothiazole necroptosis inhibitors with chiral substitutions in the solvent-accessible region of RIP kinase domain.
Bioorg Chem
; 137: 106647, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37270986
9.
Profiling of the chemical space on the phenyl group of substituted benzothiazole RIPK3 inhibitors.
Bioorg Chem
; 131: 106339, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36599218
10.
Ferroptosis inhibitor liproxstatin-1 alleviates metabolic dysfunction-associated fatty liver disease in mice: potential involvement of PANoptosis.
Acta Pharmacol Sin
; 44(5): 1014-1028, 2023 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-36323829
11.
Metabolomic profiling of cerebrospinal fluid reveals an early diagnostic model for central nervous system involvement in acute lymphoblastic leukaemia.
Br J Haematol
; 198(6): 994-1010, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35708546
12.
Structure-Based design of Marine-derived Meridianin C derivatives as glycogen synthase kinase 3ß inhibitors with improved oral bioavailability: From aminopyrimidyl-indoles to the sulfonyl analogues.
Bioorg Chem
; 119: 105537, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34902644
13.
Characterization of Different Forms of Kava (Piper methysticum) Products by UPLC-MS/MS.
Planta Med
; 88(14): 1348-1359, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-34839465
14.
Druggability modification strategies of the diarylpyrimidine-type non-nucleoside reverse transcriptase inhibitors.
Med Res Rev
; 41(3): 1255-1290, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33497504
15.
Enantiomeric profiling of a chiral benzothiazole necroptosis inhibitor.
Bioorg Med Chem Lett
; 43: 128084, 2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33964444
16.
Chemical space exploration of novel naphthyl-carboxamide-diarylpyrimidine derivatives with potent anti-HIV-1 activity.
Bioorg Chem
; 111: 104905, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33895602
17.
Structural-Based Optimizations of the Marine-Originated Meridianin C as Glucose Uptake Agents by Inhibiting GSK-3ß.
Mar Drugs
; 19(3)2021 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33809065
18.
Enantioselective Total Syntheses of (-)-20-epi-Vincamine and (-)-20-epi-Eburnamonine by Ir-Catalyzed Asymmetric Imine Hydrogenation/Lactamization Cascade.
Chemistry
; 26(46): 10439-10443, 2020 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32500532
19.
Asymmetric synthesis of (-)-solanidine and (-)-tomatidenol.
Org Biomol Chem
; 18(16): 3169-3176, 2020 04 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32270168
20.
Correction: Asymmetric synthesis of (-)-solanidine and (-)-tomatidenol.
Org Biomol Chem
; 18(21): 4114, 2020 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32441732