Detalhe da pesquisa
1.
Identification of potent inhibitors of the sortilin-progranulin interaction.
Bioorg Med Chem Lett
; 30(17): 127403, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32738972
2.
Structural characterization of nonactive site, TrkA-selective kinase inhibitors.
Proc Natl Acad Sci U S A
; 114(3): E297-E306, 2017 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28039433
3.
[(3)H]chlorpromazine photolabeling of the torpedo nicotinic acetylcholine receptor identifies two state-dependent binding sites in the ion channel.
Biochemistry
; 48(42): 10066-77, 2009 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-19754159
4.
Affinity selection-mass spectrometry screening techniques for small molecule drug discovery.
Curr Opin Chem Biol
; 11(5): 518-26, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17931956
5.
Discovery and characterization of orthosteric and allosteric muscarinic M2 acetylcholine receptor ligands by affinity selection-mass spectrometry.
J Biomol Screen
; 11(2): 194-207, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16490772
6.
2-(3-Methyl-3H-diaziren-3-yl)ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate: a derivative of the stereoselective general anesthetic etomidate for photolabeling ligand-gated ion channels.
J Med Chem
; 46(7): 1257-65, 2003 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-12646036
7.
Application of affinity selection-mass spectrometry assays to purification and affinity-based screening of the chemokine receptor CXCR4.
Comb Chem High Throughput Screen
; 15(6): 473-85, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22651846
8.
Multidimensional profiling of CSF1R screening hits and inhibitors: assessing cellular activity, target residence time, and selectivity in a higher throughput way.
J Biomol Screen
; 16(9): 1007-17, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21873591
9.
Evaluation of in vitro PXR-based assays and in silico modeling approaches for understanding the binding of a structurally diverse set of drugs to PXR.
Biochem Pharmacol
; 81(5): 669-79, 2011 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21145880
10.
Photolabeling the Torpedo nicotinic acetylcholine receptor with 4-azido-2,3,5,6-tetrafluorobenzoylcholine, a partial agonist.
Biochemistry
; 44(41): 13447-56, 2005 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-16216068
11.
Interactions of peptide mimics of hyaluronic acid with the receptor for hyaluronan mediated motility (RHAMM).
J Comput Aided Mol Des
; 18(10): 597-614, 2004 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15849992
12.
Identification of binding sites in the nicotinic acetylcholine receptor for [3H]azietomidate, a photoactivatable general anesthetic.
J Biol Chem
; 279(17): 17640-9, 2004 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-14761946
13.
Identification of amino acids in the nicotinic acetylcholine receptor agonist binding site and ion channel photolabeled by 4-[(3-trifluoromethyl)-3H-diazirin-3-yl]benzoylcholine, a novel photoaffinity antagonist.
Biochemistry
; 42(2): 271-83, 2003 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-12525154