RESUMO
The paper briefly presents clinical, epidemiological, virological and serological data on cases of Crimean-Congo hemorrhagic fever (CCHF) in Astrakhan Province. The results indicate annual infection of the regions population with CCHF virus, the main mode of transmission being vector-borne. The advantages of the fluorescence antibody technique and enzyme immunoassay-for diagnosis of the disease were demonstrated.
Assuntos
Febre Hemorrágica da Crimeia/diagnóstico , Doença Aguda , Animais , Animais Recém-Nascidos , Anticorpos Antivirais/análise , Encéfalo/imunologia , Encéfalo/microbiologia , Reservatórios de Doenças , Cobaias , Vírus da Febre Hemorrágica da Crimeia-Congo/imunologia , Vírus da Febre Hemorrágica da Crimeia-Congo/isolamento & purificação , Febre Hemorrágica da Crimeia/epidemiologia , Febre Hemorrágica da Crimeia/imunologia , Febre Hemorrágica da Crimeia/microbiologia , Humanos , Rim/imunologia , Rim/microbiologia , Fígado/imunologia , Fígado/microbiologia , Camundongos , Federação Russa/epidemiologia , Estações do Ano , Fatores de TempoRESUMO
Paper presents the results of a successful use of a solid-phase immunoassay for indication of the antigen of hemorrhagic fever-Crimean--Congo virus in lays and half-fed female-ticks Hyalomma marginatum marginatum Koch (1795) collected in endemic area, which adds to our knowledge of this disease focus activity.
Assuntos
Antígenos Virais/análise , Vetores Aracnídeos , Bunyaviridae/imunologia , Vírus da Febre Hemorrágica da Crimeia-Congo/imunologia , Febre Hemorrágica da Crimeia/diagnóstico , Animais , Técnicas ImunoenzimáticasRESUMO
The study of ixodes ticks collected in Astrakhan Province in 1982-1987 has revealed spontaneous infection with Crimean hemorrhagic fever virus in 4 species. It has been established that a proportion of the infected ck suspensions from the imago Hyalomma marginatum marginatum (a back-ground species for the given region) was 3.6% as measured by the method of mouse infection and 8.9% as measured by the enzyme immunoassay. The advantages of the enzyme immunoassay as a method for Crimean hemorrhagic fever virus identification in ticks have been demonstrated.