Detalhe da pesquisa
1.
Phase I, randomized, double-blind, placebo-controlled, multiple intravenous, dose-ascending study of sirukumab in cutaneous or systemic lupus erythematosus.
Arthritis Rheum
; 65(10): 2661-71, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23896980
2.
Pharmacokinetics and safety of sirukumab following a single subcutaneous administration to healthy Japanese and Caucasian subjects.
Int J Clin Pharmacol Ther
; 51(3): 187-99, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23357841
3.
MANTA and MANTA-RAy: Rationale and Design of Trials Evaluating Effects of Filgotinib on Semen Parameters in Patients with Inflammatory Diseases.
Adv Ther
; 39(7): 3403-3422, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35614292
4.
Evaluation of disease-mediated therapeutic protein-drug interactions between an anti-interleukin-6 monoclonal antibody (sirukumab) and cytochrome P450 activities in a phase 1 study in patients with rheumatoid arthritis using a cocktail approach.
J Clin Pharmacol
; 55(12): 1386-94, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26054042
5.
Golimumab pharmacokinetics after repeated subcutaneous and intravenous administrations in patients with rheumatoid arthritis and the effect of concomitant methotrexate: an open-label, randomized study.
Clin Ther
; 34(1): 77-90, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22169051
6.
Photoprovocation in cutaneous lupus erythematosus: a multicenter study evaluating a standardized protocol.
J Invest Dermatol
; 131(8): 1622-30, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21593767
7.
Age and sex effects on the single- and multiple-dose safety and pharmacokinetics of the new rennin inhibitor ACT-178882.
Cardiovasc Ther
; 31(6): e86-7, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23889900