Ménétrier disease: a rare cause of severe chronic diarrhea difficult to diagnose with response to treatment with octreotide.

We present the case of a 71-year-old male with difficult to manage severe chronic diarrhea, who after multiple tests was finally diagnosed with Ménétrier's disease and had clinical improvement with treatment with intramuscular octreotide. A high degree of clinical suspicion is essential to diagnose this entity, exclude similar entities and the correlation of clinical, analytical, endoscopic, radiological and histological data.

Sarcina ventriculi in gastric biopsies of two patients with an underlying neoplasia.

We present the cases of two women aged 75 and 71 years under study for dyspepsia and weight loss. The initial gastroscopy of both patients showed a stomach full of food content, with thickened gastric folds that were hard on contact with the forceps. Gastric biopsies showed the presence of Sarcina ventriculi on active chronic gastritis, so antibiotic treatment was started (ciprofloxacin and metronidazole), without significant clinical improvement. In both patients, gastroscopy was repeated without showing macroscopic changes compared to the initial gastroscopy, which led to the suspicion of an underlying lesion.