Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 23
Filtrar
1.
Int J Eat Disord ; 55(10): 1361-1373, 2022 10.
Artigo em Inglês | MEDLINE | ID: mdl-35906929

RESUMO

OBJECTIVE: Many individuals with an eating disorder do not receive appropriate care. Low-threshold interventions could help bridge this treatment gap. The study aim was to evaluate the effectiveness of Featback, a fully automated online self-help intervention, online expert-patient support and their combination. METHOD: A randomized controlled trial with a 12-month follow-up period was conducted. Participants aged 16 or older with at least mild eating disorder symptoms were randomized to four conditions: (1) Featback, a fully automated online self-help intervention, (2) chat or email support from a recovered expert patient, (3) Featback with expert-patient support and (4) a waiting list control condition. The intervention period was 8 weeks and there was a total of six online assessments. The main outcome constituted reduction of eating disorder symptoms over time. RESULTS: Three hundred fifty five participants, of whom 43% had never received eating disorder treatment, were randomized. The three active interventions were superior to a waitlist in reducing eating disorder symptoms (d = -0.38), with no significant difference in effectiveness between the three interventions. Participants in conditions with expert-patient support were more satisfied with the intervention. DISCUSSION: Internet-based self-help, expert-patient support and their combination were effective in reducing eating disorder symptoms compared to a waiting list control condition. Guidance improved satisfaction with the internet intervention but not its effectiveness. Low-threshold interventions such as Featback and expert-patient support can reduce eating disorder symptoms and reach the large group of underserved individuals, complementing existing forms of eating disorder treatment. PUBLIC SIGNIFICANCE STATEMENT: Individuals with eating-related problems who received (1) a fully automated internet-based intervention, (2) chat and e-mail support by a recovered individual or (3) their combination, experienced stronger reductions in eating disorder symptoms than those who received (4) usual care. Such brief and easy-access interventions play an important role in reaching individuals who are currently not reached by other forms of treatment.


Assuntos
Transtornos da Alimentação e da Ingestão de Alimentos , Intervenção Baseada em Internet , Transtornos da Alimentação e da Ingestão de Alimentos/terapia , Comportamentos Relacionados com a Saúde , Humanos , Internet , Resultado do Tratamento , Listas de Espera
2.
Int J Eat Disord ; 55(8): 1143-1155, 2022 08.
Artigo em Inglês | MEDLINE | ID: mdl-35748112

RESUMO

OBJECTIVE: The primary aim was assessing the cost-effectiveness of an internet-based self-help program, expert-patient support, and the combination of both compared to a care-as-usual condition. METHOD: An economic evaluation from a societal perspective was conducted alongside a randomized controlled trial. Participants aged 16 or older with at least mild eating disorder symptoms were randomly assigned to four conditions: (1) Featback, an online unguided self-help program, (2) chat or e-mail support from a recovered expert patient, (3) Featback with expert-patient support, and (4) care-as-usual. After a baseline assessment and intervention period of 8 weeks, five online assessments were conducted over 12 months of follow-up. The main result constituted cost-utility acceptability curves with quality-of-life adjusted life years (QALYs) and societal costs over the entire study duration. RESULTS: No significant differences between the conditions were found regarding QALYs, health care costs and societal costs. Nonsignificant differences in QALYs were in favor of the Featback conditions and the lowest societal costs per participant were observed in the Featback only condition (€16,741) while the highest costs were seen in the care-as-usual condition (€28,479). The Featback only condition had the highest probability of being efficient compared to the alternatives for all acceptable willingness-to-pay values. DISCUSSION: Featback, an internet-based unguided self-help intervention, was likely to be efficient compared to Featback with guidance from an expert patient, guidance alone and a care-as-usual condition. Results suggest that scalable interventions such as Featback may reduce health care costs and help individuals with eating disorders that are currently not reached by other forms of treatment. PUBLIC SIGNIFICANCE STATEMENT: Internet-based interventions for eating disorders might reach individuals in society who currently do not receive appropriate treatment at low costs. Featback, an online automated self-help program for eating disorders, was found to improve quality of life slightly while reducing costs for society, compared to a do-nothing approach. Consequently, implementing internet-based interventions such as Featback likely benefits both individuals suffering from an eating disorder and society as a whole.


Assuntos
Transtornos da Alimentação e da Ingestão de Alimentos , Intervenção Baseada em Internet , Análise Custo-Benefício , Transtornos da Alimentação e da Ingestão de Alimentos/terapia , Humanos , Internet , Qualidade de Vida , Anos de Vida Ajustados por Qualidade de Vida
3.
J Pers Assess ; 102(3): 297-308, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-30657714

RESUMO

Missing data is a problem that occurs frequently in many scientific areas. The most sophisticated method for dealing with this problem is multiple imputation. Contrary to other methods, like listwise deletion, this method does not throw away information, and partly repairs the problem of systematic dropout. Although from a theoretical point of view multiple imputation is considered to be the optimal method, many applied researchers are reluctant to use it because of persistent misconceptions about this method. Instead of providing an(other) overview of missing data methods, or extensively explaining how multiple imputation works, this article aims specifically at rebutting these misconceptions, and provides applied researchers with practical arguments supporting them in the use of multiple imputation.


Assuntos
Interpretação Estatística de Dados , Projetos de Pesquisa , Humanos
4.
Multivariate Behav Res ; 54(4): 514-529, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30822143

RESUMO

Whenever multiple regression is applied to a multiply imputed data set, several methods for combining significance tests for R2 and the change in R2 across imputed data sets may be used: the combination rules by Rubin, the Fisher z-test for R2 by Harel, and F-tests for the change in R2 by Chaurasia and Harel. For pooling R2 itself, Harel proposed a method based on a Fisher z transformation. In the current article, it is argued that the pooled R2 based on the Fisher z transformation, the Fisher z-test for R2 , and the F-test for the change in R2 have some theoretical flaws. An argument is made for using Rubin's method for pooling significance tests for R2 instead, and alternative procedures for pooling R2 are proposed: simple averaging and a pooled R2 constructed from the pooled significance test by Rubin. Simulations show that the Fisher z-test and Chaurasia and Harel's F-tests generally give inflated type-I error rates, whereas the type-I error rates of Rubin's method are correct. Of the methods for pooling the point estimates of R2 no method clearly performs best, but it is argued that the average of R2 's across imputed data set is preferred.


Assuntos
Algoritmos , Interpretação Estatística de Dados , Modelos Estatísticos , Humanos , Análise Multivariada
5.
Eur J Pediatr ; 175(5): 715-25, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-26847428

RESUMO

UNLABELLED: Empirical evidence has shown that international adoptees present physical growth delays, precocious puberty, behavioral problems, and mental health referrals more often than non-adoptees. We hypothesized that the higher prevalence of (mental) health problems in adoptees is accompanied by elevated consumption of prescription drugs, including antidepressants, attention deficit hyperactivity disorder (ADHD) medication, and medication for growth inhibition/stimulation. In an archival, population-based Dutch cohort study, data on medication use were available from the Health Care Insurance Board by Statistics Netherlands from 2006 to 2011. The Dutch population born between 1994 and 2005 and alive during the period of measurement was included (2,360,450 including 10,602 international adoptees, of which 4447 from China). Their mean age was 6.5 years at start (range 1-12 years) and 11.5 years at the end of the measurement period (range 6-17 years). Chinese female adoptees used less medication for precocious puberty (as treatment for precocious puberty; odds ratio (OR) = 0.57, effect size Cohen's d = -0.31) and contraception (OR = 0.65, d = -0.24) than non-adoptees. For both males and females, non-Chinese adoptees used more medication for ADHD than non-adoptees (males: OR = 1.22, females: OR = 1.32), but the effect was small (males: d = 0.11, females: d = 0.15). CONCLUSIONS: Adoptees in the Netherlands generally do not use more medication than their non-adopted peers. WHAT IS KNOWN: • Meta-analytical evidence shows that international adoptees present physical growth delays and mental health referrals more often than non-adopted controls. • With the exception of one Swedish study on ADHD medication, there is no other systematic research on medication use of international adoptees. What is New: • All differences in medication use between international adoptees in the Netherlands and non-adopted controls were below the threshold of a small effect with the exception of medication for precocious puberty, but this effect was in the opposite direction with female adoptees using less medication for precocious puberty than non-adoptees. • International adoptees in the Netherlands do not use more medication despite experiences of preadoption adversity and higher rates of mental health referrals during childhood and adolescence.


Assuntos
Adoção , Comportamento Infantil , Usuários de Drogas/estatística & dados numéricos , Adolescente , Criança , Pré-Escolar , Feminino , Seguimentos , Humanos , Lactente , Masculino , Países Baixos , Razão de Chances , Prevalência , Estudos Retrospectivos
6.
J Med Internet Res ; 18(6): e159, 2016 06 17.
Artigo em Inglês | MEDLINE | ID: mdl-27317358

RESUMO

BACKGROUND: Despite the disabling nature of eating disorders (EDs), many individuals with ED symptoms do not receive appropriate mental health care. Internet-based interventions have potential to reduce the unmet needs by providing easily accessible health care services. OBJECTIVE: This study aimed to investigate the effectiveness of an Internet-based intervention for individuals with ED symptoms, called "Featback." In addition, the added value of different intensities of therapist support was investigated. METHODS: Participants (N=354) were aged 16 years or older with self-reported ED symptoms, including symptoms of anorexia nervosa, bulimia nervosa, and binge eating disorder. Participants were recruited via the website of Featback and the website of a Dutch pro-recovery-focused e-community for young women with ED problems. Participants were randomized to: (1) Featback, consisting of psychoeducation and a fully automated self-monitoring and feedback system, (2) Featback supplemented with low-intensity (weekly) digital therapist support, (3) Featback supplemented with high-intensity (3 times a week) digital therapist support, and (4) a waiting list control condition. Internet-administered self-report questionnaires were completed at baseline, post-intervention (ie, 8 weeks after baseline), and at 3- and 6-month follow-up. The primary outcome measure was ED psychopathology. Secondary outcome measures were symptoms of depression and anxiety, perseverative thinking, and ED-related quality of life. Statistical analyses were conducted according to an intent-to-treat approach using linear mixed models. RESULTS: The 3 Featback conditions were superior to a waiting list in reducing bulimic psychopathology (d=-0.16, 95% confidence interval (CI)=-0.31 to -0.01), symptoms of depression and anxiety (d=-0.28, 95% CI=-0.45 to -0.11), and perseverative thinking (d=-0.28, 95% CI=-0.45 to -0.11). No added value of therapist support was found in terms of symptom reduction although participants who received therapist support were significantly more satisfied with the intervention than those who did not receive supplemental therapist support. No significant differences between the Featback conditions supplemented with low- and high-intensity therapist support were found regarding the effectiveness and satisfaction with the intervention. CONCLUSIONS: The fully automated Internet-based self-monitoring and feedback intervention Featback was effective in reducing ED and comorbid psychopathology. Supplemental therapist support enhanced satisfaction with the intervention but did not increase its effectiveness. Automated interventions such as Featback can provide widely disseminable and easily accessible care. Such interventions could be incorporated within a stepped-care approach in the treatment of EDs and help to bridge the gap between mental disorders and mental health care services. TRIAL REGISTRATION: Netherlands Trial Registry: NTR3646; http://www.trialregister.nl/trialreg/admin/ rctview.asp?TC=3646 (Archived by WebCite at http://www.webcitation.org/6fgHTGKHE).


Assuntos
Transtornos da Alimentação e da Ingestão de Alimentos/terapia , Comportamentos Relacionados com a Saúde , Internet , Telemedicina/métodos , Adulto , Transtornos da Alimentação e da Ingestão de Alimentos/psicologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Qualidade de Vida , Grupos de Autoajuda , Inquéritos e Questionários
7.
Multivariate Behav Res ; 49(1): 78-91, 2014 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-24860197

RESUMO

As a procedure for handling missing data, Multiple imputation consists of estimating the missing data multiple times to create several complete versions of an incomplete data set. All these data sets are analyzed by the same statistical procedure, and the results are pooled for interpretation. So far, no explicit rules for pooling F-tests of (repeated-measures) analysis of variance have been defined. In this paper we outline the appropriate procedure for the results of analysis of variance for multiply imputed data sets. It involves both reformulation of the ANOVA model as a regression model using effect coding of the predictors and applying already existing combination rules for regression models. The proposed procedure is illustrated using three example data sets. The pooled results of these three examples provide plausible F- and p-values.

8.
Artigo em Inglês | MEDLINE | ID: mdl-38578020

RESUMO

The proportion of explained variance is an important statistic in multiple regression for determining how well the outcome variable is predicted by the predictors. Earlier research on 20 different estimators for the proportion of explained variance, including the exact Olkin-Pratt estimator and the Ezekiel estimator, showed that the exact Olkin-Pratt estimator produced unbiased estimates, and was recommended as a default estimator. In the current study, the same 20 estimators were studied in incomplete data, with missing data being treated using multiple imputation. In earlier research on the proportion of explained variance in multiply imputed data sets, an estimator called R ̂ SP 2 $$ {\hat{R}}_{\mathrm{SP}}^2 $$ was shown to be the preferred pooled estimator for regular R 2 $$ {R}^2 $$ . For each of the 20 estimators in the current study, two pooled estimators were proposed: one where the estimator was the average across imputed data sets, and one where R ̂ SP 2 $$ {\hat{R}}_{\mathrm{SP}}^2 $$ was used as input for the calculation of the specific estimator. Simulations showed that estimates based on R ̂ SP 2 $$ {\hat{R}}_{\mathrm{SP}}^2 $$ performed best regarding bias and accuracy, and that the Ezekiel estimator was generally the least biased. However, none of the estimators were unbiased at all times, including the exact Olkin-Pratt estimator based on R ̂ SP 2 $$ {\hat{R}}_{\mathrm{SP}}^2 $$ .

9.
BJPsych Open ; 8(3): e81, 2022 Apr 07.
Artigo em Inglês | MEDLINE | ID: mdl-35388780

RESUMO

BACKGROUND: A variety of information sources are used in the best-evidence diagnostic procedure in child and adolescent mental healthcare, including evaluation by referrers and structured assessment questionnaires for parents. However, the incremental value of these information sources is still poorly examined. AIMS: To quantify the added and unique predictive value of referral letters, screening, multi-informant assessment and clinicians' remote evaluations in predicting mental health disorders. METHOD: Routine medical record data on 1259 referred children and adolescents were retrospectively extracted. Their referral letters, responses to the Strengths and Difficulties Questionnaire (SDQ), results on closed-ended questions from the Development and Well-Being Assessment (DAWBA) and its clinician-rated version were linked to classifications made after face-to-face intake in psychiatry. Following multiple imputations of missing data, logistic regression analyses were performed with the above four nodes of assessment as predictors and the five childhood disorders common in mental healthcare (anxiety, depression, autism spectrum disorders, attention-deficit hyperactivity disorder, behavioural disorders) as outcomes. Likelihood ratio tests and diagnostic odds ratios were computed. RESULTS: Each assessment tool significantly predicted the classified outcome. Successive addition of the assessment instruments improved the prediction models, with the exception of behavioural disorder prediction by the clinician-rated DAWBA. With the exception of the SDQ for depressive and behavioural disorders, all instruments showed unique predictive value. CONCLUSIONS: Structured acquisition and integrated use of diverse sources of information supports evidence-based diagnosis in clinical practice. The clinical value of structured assessment at the primary-secondary care interface should now be quantified in prospective studies.

10.
Psychometrika ; 85(1): 185-205, 2020 03.
Artigo em Inglês | MEDLINE | ID: mdl-32162232

RESUMO

Whenever statistical analyses are applied to multiply imputed datasets, specific formulas are needed to combine the results into one overall analysis, also called combination rules. In the context of regression analysis, combination rules for the unstandardized regression coefficients, the t-tests of the regression coefficients, and the F-tests for testing [Formula: see text] for significance have long been established. However, there is still no general agreement on how to combine the point estimators of [Formula: see text] in multiple regression applied to multiply imputed datasets. Additionally, no combination rules for standardized regression coefficients and their confidence intervals seem to have been developed at all. In the current article, two sets of combination rules for the standardized regression coefficients and their confidence intervals are proposed, and their statistical properties are discussed. Additionally, two improved point estimators of [Formula: see text] in multiply imputed data are proposed, which in their computation use the pooled standardized regression coefficients. Simulations show that the proposed pooled standardized coefficients produce only small bias and that their 95% confidence intervals produce coverage close to the theoretical 95%. Furthermore, the simulations show that the newly proposed pooled estimates for [Formula: see text] are less biased than two earlier proposed pooled estimates.


Assuntos
Simulação por Computador/estatística & dados numéricos , Intervalos de Confiança , Análise de Regressão , Algoritmos , Interpretação Estatística de Dados , Humanos , Modelos Estatísticos , Análise Multivariada , Projetos de Pesquisa
11.
PLoS One ; 15(3): e0225839, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32163421

RESUMO

In the current study a three-generational design was used to investigate intergenerational transmission of child maltreatment (ITCM) using multiple sources of information on child maltreatment: mothers, fathers and children. A total of 395 individuals from 63 families reported on maltreatment. Principal Component Analysis (PCA) was used to combine data from mother, father and child about maltreatment that the child had experienced. This established components reflecting the convergent as well as the unique reports of father, mother and child on the occurrence of maltreatment. Next, we tested ITCM using the multi-informant approach and compared the results to those of two more common approaches: ITCM based on one reporter and ITCM based on different reporters from each generation. Results of our multi-informant approach showed that a component reflecting convergence between mother, father, and child reports explained most of the variance in experienced maltreatment. For abuse, intergenerational transmission was consistently found across approaches. In contrast, intergenerational transmission of neglect was only found using the perspective of a single reporter, indicating that transmission of neglect might be driven by reporter effects. In conclusion, the present results suggest that including multiple informants may be necessary to obtain more valid estimates of ITCM.


Assuntos
Sobreviventes Adultos de Maus-Tratos Infantis/psicologia , Maus-Tratos Infantis/psicologia , Pai/psicologia , Relação entre Gerações , Relações Mãe-Filho/psicologia , Mães/psicologia , Adulto , Criança , Pré-Escolar , Humanos
13.
Trials ; 20(1): 509, 2019 Aug 16.
Artigo em Inglês | MEDLINE | ID: mdl-31420063

RESUMO

BACKGROUND: E-mental health has become increasingly popular in interventions for individuals with eating disorders (EDs). It has the potential to offer low-threshold interventions and guide individuals to the needed care more promptly. Featback is such an Internet-based intervention and consists of psychoeducation and a fully automated monitoring and feedback system. Preliminary findings suggest Featback to be (cost-)effective in reducing ED symptomatology. Additionally, e-mail or chat support by a psychologist did not enhance the effectiveness of Featback. Support by an expert patient (someone with a lived experience of an ED) might be more effective, since that person can effectively model healthy behavior and enhance self-efficacy in individuals struggling with an ED. The present study aims to replicate and build on earlier findings by further investigating the (cost-)effectiveness of Featback and the added value of expert-patient support. METHODS: The study will be a randomized controlled trial with a two-by-two factorial design with repeated measures. The four conditions will be (1) Featback, in which participants receive automated feedback on a short monitoring questionnaire weekly, (2) Featback with weekly e-mail or chat support from an expert patient, (3) weekly support from an expert patient, and (4) a waiting list. Participants who are 16 years or older and have at least mild self-reported ED symptoms receive a baseline measure. Subsequently, they are randomized to one of the four conditions for 8 weeks. Participants will be assessed again post-intervention and at 3, 6, 9, and 12 months follow-up. The primary outcome measure will be ED psychopathology. Secondary outcome measures are experienced social support, self-efficacy, symptoms of anxiety and depression, user satisfaction, intervention usage, and help-seeking attitudes and behaviors. DISCUSSION: The current study is the first to investigate e-mental health in combination with expert-patient support for EDs and will add to the optimization of the delivery of Internet-based interventions and expert-patient support. TRIAL REGISTRATION: Netherlands Trial Register, NTR7065 . Registered on 7 June 2018.


Assuntos
Transtornos da Alimentação e da Ingestão de Alimentos/terapia , Intervenção Baseada em Internet , Ensaios Clínicos Controlados Aleatórios como Assunto , Apoio Social , Adolescente , Transtornos da Alimentação e da Ingestão de Alimentos/psicologia , Feminino , Comportamento de Busca de Ajuda , Humanos , Avaliação de Resultados em Cuidados de Saúde , Qualidade de Vida , Adulto Jovem
14.
Br J Math Stat Psychol ; 60(Pt 2): 315-37, 2007 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-17971272

RESUMO

Multiple imputation under a two-way model with error is a simple and effective method that has been used to handle missing item scores in unidimensional test and questionnaire data. Extensions of this method to multidimensional data are proposed. A simulation study is used to investigate whether these extensions produce biased estimates of important statistics in multidimensional data, and to compare them with lower benchmark listwise deletion, two-way with error and multivariate normal imputation. The new methods produce smaller bias in several psychometrically interesting statistics than the existing methods of two-way with error and multivariate normal imputation. One of these new methods clearly is preferable for handling missing item scores in multidimensional test data.


Assuntos
Interpretação Estatística de Dados , Modelos Psicológicos , Psicologia/métodos , Psicologia/estatística & dados numéricos , Análise Fatorial , Humanos
15.
JMIR Diabetes ; 2(2): e21, 2017 Aug 24.
Artigo em Inglês | MEDLINE | ID: mdl-30291059

RESUMO

BACKGROUND: Three recent reviews evaluated 19 studies testing the hemoglobin A1c (HbA1c) benefit of 16 diabetes apps, including 5 publicly available apps. Most studies relied on small samples and did not link app engagement with outcomes. OBJECTIVE: This study assessed both HbA1c change in a large sample of people using the One Drop | Mobile app and associations between app engagement and changes in HbA1c. METHODS: The One Drop | Mobile app for iOS and Android is designed to manually and passively (via Apple HealthKit, Google Fit, and the One Drop | Chrome blood glucose meter) store, track, and share data. Users can schedule medication reminders, view statistics, set goals, track health outcomes, and get data-driven insights. In June 2017, we queried data on people with diabetes using the app who had entered at least 2 HbA1c values in the app >60 and ≤365 days apart. Multiple imputation corrected for missing data. Unadjusted and adjusted mixed effects repeated measures models tested mean HbA1c change by time, diabetes type, and their interaction. Multiple regression models assessed relationships between using the app to track food, activity, blood glucose, and medications and HbA1c change. RESULTS: The sample (N=1288) included people with type 1 diabetes (T1D) (n=367) or type 2 diabetes (T2D) (n=921) who were 35% female, diagnosed with diabetes for a mean 9.4 (SD 9.9) years, and tracked an average 1646.1 (SD 3621.9) self-care activities in One Drop | Mobile between their first (mean 8.14% [SD 2.06%]) and second HbA1c entry (mean 6.98% [SD 1.1%]). HbA1c values were significantly associated with user-entered average blood glucose 90 days before the second HbA1c entry (rho=.73 to .75, P<.001). HbA1c decreased by an absolute 1.07% (unadjusted and adjusted F=292.03, P<.001) from first to second HbA1c entry. There was a significant interaction between diabetes type and HbA1c. Both groups significantly improved, but users with T2D had a greater HbA1c decrease over time than users with T1D (F=10.54, P<.001). For users with T2D (n=921), HbA1c decreased by an absolute 1.27% (F=364.50, P<.001) from first to second HbA1c entry. Finally, using One Drop | Mobile to record food was associated with greater HbA1c reductions even after adjusting for covariates and after also adjusting for insulin use for users with T2D (all P<.05). CONCLUSIONS: People with T1D and T2D reported a 1.07% to 1.27% absolute reduction in HbA1c during a median 4 months of using the One Drop | Mobile app. Using the app to track self-care was associated with improved HbA1c. More research is needed on the health benefits of publicly available diabetes apps, particularly studies associating app engagement with short- and long-term effects.

16.
JMIR Mhealth Uhealth ; 5(11): e179, 2017 Nov 29.
Artigo em Inglês | MEDLINE | ID: mdl-29187344

RESUMO

BACKGROUND: The One Drop | Mobile app supports manual and passive (via HealthKit and One Drop's glucose meter) tracking of self-care and glycated hemoglobin A1c (HbA1c). OBJECTIVE: We assessed the HbA1c change of a sample of people with type 1 diabetes (T1D) or type 2 diabetes (T2D) using the One Drop | Mobile app on iPhone and Apple Watch, and tested relationships between self-care tracking with the app and HbA1c change. METHODS: In June 2017, we identified people with diabetes using the One Drop | Mobile app on iPhone and Apple Watch who entered two HbA1c measurements in the app 60 to 365 days apart. We assessed the relationship between using the app and HbA1c change. RESULTS: Users had T1D (n=65) or T2D (n=191), were 22.7% (58/219) female, with diabetes for a mean 8.34 (SD 8.79) years, and tracked a mean 2176.35 (SD 3430.23) self-care activities between HbA1c entries. There was a significant 1.36% or 14.9 mmol/mol HbA1c reduction (F=62.60, P<.001) from the first (8.72%, 71.8 mmol/mol) to second HbA1c (7.36%, 56.9 mmol/mol) measurement. Tracking carbohydrates was independently associated with greater HbA1c improvement (all P<.01). CONCLUSIONS: Using One Drop | Mobile on iPhone and Apple Watch may favorably impact glycemic control.

17.
Psychophysiology ; 50(2): 195-203, 2013 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-23252764

RESUMO

We examined associations of disorganized attachment and maternal depressive symptoms with infant autonomic functioning in 450 infant-mother dyads enrolled in the Generation R study. Maternal depressive symptoms were measured 2 months postpartum with the Brief Symptom Inventory. At 14 months, we assessed infant attachment with a slightly shortened Strange Situation and measured infant resting heart rate. Respiratory sinus arrhythmia (RSA) was calculated using spectral analysis. Higher levels of maternal postnatal depressive symptoms predicted lower resting RSA in disorganized infants (B = -0.31, SE = 0.15, p = .04, R(2) = .05) but not in nondisorganized infants (B = 0.05, SE = 0.06, p = .36). This effect was buffered in disorganized infants with a secondary secure attachment classification. Disorganized infants were more vulnerable to the effect of maternal postnatal depressive symptoms on the physiological stress systems.


Assuntos
Sistema Nervoso Autônomo/fisiologia , Depressão/psicologia , Comportamento Materno/fisiologia , Comportamento Materno/psicologia , Relações Mãe-Filho , Apego ao Objeto , Arritmia Sinusal/fisiopatologia , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Idade Materna , Escalas de Graduação Psiquiátrica , Estresse Fisiológico/fisiologia
18.
Br J Math Stat Psychol ; 64(3): 498-515, 2011 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-21973098

RESUMO

Earlier research has shown that bootstrap confidence intervals from principal component loadings give a good coverage of the population loadings. However, this only applies to complete data. When data are incomplete, missing data have to be handled before analysing the data. Multiple imputation may be used for this purpose. The question is how bootstrap confidence intervals for principal component loadings should be corrected for multiply imputed data. In this paper, several solutions are proposed. Simulations show that the proposed corrections for multiply imputed data give a good coverage of the population loadings in various situations.


Assuntos
Intervalos de Confiança , Análise de Componente Principal , Ansiedade de Separação/epidemiologia , Simulação por Computador/estatística & dados numéricos , Interpretação Estatística de Dados , Humanos , Modelos Estatísticos , Projetos de Pesquisa , Tamanho da Amostra
19.
An. psicol ; 32(2): 596-608, mayo 2016. graf, tab
Artigo em Inglês | IBECS (Espanha) | ID: ibc-151715

RESUMO

Researchers frequently have to analyze scales in which some participants have failed to respond to some items. In this paper we focus on the exploratory factor analysis of multidimensional scales (i.e., scales that consist of a number of subscales) where each subscale is made up of a number of Likert-type items, and the aim of the analysis is to estimate participants’ scores on the corresponding latent traits. We propose a new approach to deal with missing responses in such a situation that is based on (1) multiple imputations of non-responses and (2) simultaneous rotation of the imputed datasets. We applied the approach in a real dataset where missing responses were artificially introduced following a real pattern of non-responses, and a simulation study based on artificial datasets. The results show that our approach (specifically, Hot-Deck multiple imputation followed of Consensus Promin rotation) was able to successfully compute factor score estimates even for participants that have missing data


Imputación múltiple de valores perdidos en el análisis factorial exploratorio de escalas multidimensionales: estimación de las puntuaciones de rasgos latentes. Resumen: Los investigadores con frecuencia se enfrentan a la difícil tarea de analizar las escalas en las que algunos de los participantes no han respondido a todos los ítems. En este artículo nos centramos en el análisis factorial exploratorio de escalas multidimensionales (es decir, escalas que constan de varias de subescalas), donde cada subescala se compone de una serie de ítems de tipo Likert, y el objetivo del análisis es estimar las puntuaciones de los participantes en los rasgos latentes correspondientes. En este contexto, se propone un nuevo enfoque para hacer frente a las respuestas faltantes que se basa en (1) la imputación múltiple de las respuestas faltantes y (2) la rotación simultánea de las muestras de datos imputados. Se ha aplicado el método en una muestra de datos reales en que las respuestas que faltantes fueron introducidas artificialmente siguiendo un patrón real de respuestas faltantes, y un estudio de simulación basado en conjuntos de datos artificiales. Los resultados muestran que nuestro enfoque (en concreto, Hot-Deck de imputación múltiple seguido de rotación Consensus Promin) es capaz de calcular correctamente la puntuación factorial estimada incluso para los participantes que tienen valores perdidos


Assuntos
Humanos , Psicometria/métodos , Interpretação Estatística de Dados , Análise Fatorial , Ciências do Comportamento/estatística & dados numéricos , Reprodutibilidade dos Testes , Reprodutibilidade dos Testes
20.
Multivariate Behav Res ; 45(3): 574-98, 2010 May 28.
Artigo em Inglês | MEDLINE | ID: mdl-26760493

RESUMO

The performance of multiple imputation in questionnaire data has been studied in various simulation studies. However, in practice, questionnaire data are usually more complex than simulated data. For example, items may be counterindicative or may have unacceptably low factor loadings on every subscale, or completely missing subscales may complicate computations. In this article, it was studied how well multiple imputation recovered the results of several psychometrically important statistics in a data set with such properties. Analysis of this data set revealed that multiple imputation was able to recover the results of these analyses well. Also, a simulation study showed that multiple imputation produced small bias in these statistics for simulated data sets with the same properties.

SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA