Pesquisa | Biblioteca Virtual em Saúde

1.

Inadequate DNA Damage Repair Promotes Mammary Transdifferentiation, Leading to BRCA1 Breast Cancer.

Wang, Hua; Xiang, Dongxi; Liu, Ben; He, Aina; Randle, Helena J; Zhang, Kelvin Xi; Dongre, Anushka; Sachs, Norman; Clark, Allison P; Tao, Luwei; Chen, Qing; Botchkarev, Vladimir V; Xie, Ying; Dai, Ning; Clevers, Hans; Li, Zhe; Livingston, David M.

Cell ; 178(1): 135-151.e19, 2019 06 27.

Artigo em Inglês | MEDLINE | ID: mdl-31251913

2.

Structures of DPAGT1 Explain Glycosylation Disease Mechanisms and Advance TB Antibiotic Design.

Dong, Yin Yao; Wang, Hua; Pike, Ashley C W; Cochrane, Stephen A; Hamedzadeh, Sadra; Wyszynski, Filip J; Bushell, Simon R; Royer, Sylvain F; Widdick, David A; Sajid, Andaleeb; Boshoff, Helena I; Park, Yumi; Lucas, Ricardo; Liu, Wei-Min; Lee, Seung Seo; Machida, Takuya; Minall, Leanne; Mehmood, Shahid; Belaya, Katsiaryna; Liu, Wei-Wei; Chu, Amy; Shrestha, Leela; Mukhopadhyay, Shubhashish M M; Strain-Damerell, Claire; Chalk, Rod; Burgess-Brown, Nicola A; Bibb, Mervyn J; Barry Iii, Clifton E; Robinson, Carol V; Beeson, David; Davis, Benjamin G; Carpenter, Elisabeth P.

Cell ; 175(4): 1045-1058.e16, 2018 11 01.

Artigo em Inglês | MEDLINE | ID: mdl-30388443

3.

PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1⁺CD38^hi cells and anti-PD-1 resistance.

Verma, Vivek; Shrimali, Rajeev K; Ahmad, Shamim; Dai, Winjie; Wang, Hua; Lu, Sumin; Nandre, Rahul; Gaur, Pankaj; Lopez, Jose; Sade-Feldman, Moshe; Yizhak, Keren; Bjorgaard, Stacey L; Flaherty, Keith T; Wargo, Jennifer A; Boland, Genevieve M; Sullivan, Ryan J; Getz, Gad; Hammond, Scott A; Tan, Ming; Qi, Jingjing; Wong, Phillip; Merghoub, Taha; Wolchok, Jedd; Hacohen, Nir; Janik, John E; Mkrtichyan, Mikayel; Gupta, Seema; Khleif, Samir N.

Nat Immunol ; 20(9): 1231-1243, 2019 09.

Artigo em Inglês | MEDLINE | ID: mdl-31358999

4.

Author Correction: PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1⁺CD38^hi cells and anti-PD-1 resistance.

Verma, Vivek; Shrimali, Rajeev K; Ahmad, Shamim; Dai, Winjie; Wang, Hua; Lu, Sumin; Nandre, Rahul; Gaur, Pankaj; Lopez, Jose; Sade-Feldman, Moshe; Yizhak, Keren; Bjorgaard, Stacey L; Flaherty, Keith T; Wargo, Jennifer A; Boland, Genevieve M; Sullivan, Ryan J; Getz, Gad; Hammond, Scott A; Tan, Ming; Qi, Jingjing; Wong, Phillip; Merghoub, Taha; Wolchok, Jedd; Hacohen, Nir; Janik, John E; Mkrtichyan, Mikayel; Gupta, Seema; Khleif, Samir N.

Nat Immunol ; 20(11): 1555, 2019 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-31551574

5.

Blockade of the checkpoint receptor TIGIT prevents NK cell exhaustion and elicits potent anti-tumor immunity.

Zhang, Qing; Bi, Jiacheng; Zheng, Xiaodong; Chen, Yongyan; Wang, Hua; Wu, Wenyong; Wang, Zhengguang; Wu, Qiang; Peng, Hui; Wei, Haiming; Sun, Rui; Tian, Zhigang.

Nat Immunol ; 19(7): 723-732, 2018 07.

Artigo em Inglês | MEDLINE | ID: mdl-29915296

6.

Phonics training for English-speaking poor readers.

McArthur, Genevieve; Sheehan, Yumi; Badcock, Nicholas A; Francis, Deanna A; Wang, Hua-Chen; Kohnen, Saskia; Banales, Erin; Anandakumar, Thushara; Marinus, Eva; Castles, Anne.

Cochrane Database Syst Rev ; 11: CD009115, 2018 11 14.

Artigo em Inglês | MEDLINE | ID: mdl-30480759

7.

Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma.

Shi, Yufeng; Lim, S Kyun; Liang, Qiren; Iyer, Swathi V; Wang, Hua-Yu; Wang, Zilai; Xie, Xuanhua; Sun, Daochun; Chen, Yu-Jung; Tabar, Viviane; Gutin, Philip; Williams, Noelle; De Brabander, Jef K; Parada, Luis F.

Nature ; 567(7748): 341-346, 2019 03.

Artigo em Inglês | MEDLINE | ID: mdl-30842654

8.

BRCA1/FANCD2/BRG1-Driven DNA Repair Stabilizes the Differentiation State of Human Mammary Epithelial Cells.

Wang, Hua; Bierie, Brian; Li, Andrew G; Pathania, Shailja; Toomire, Kimberly; Dimitrov, Stoil D; Liu, Ben; Gelman, Rebecca; Giobbie-Hurder, Anita; Feunteun, Jean; Polyak, Kornelia; Livingston, David M.

Mol Cell ; 63(2): 277-292, 2016 07 21.

Artigo em Inglês | MEDLINE | ID: mdl-27373334

9.

The receptor-like kinases BAM1 and BAM2 are required for root xylem patterning.

Fan, Pengfei; Aguilar, Emmanuel; Bradai, Mariem; Xue, Hao; Wang, Hua; Rosas-Diaz, Tabata; Tang, Weihua; Wolf, Sebastian; Zhang, Heng; Xu, Lin; Lozano-Durán, Rosa.

Proc Natl Acad Sci U S A ; 118(12)2021 Mar 23.

Artigo em Inglês | MEDLINE | ID: mdl-33723062

10.

Modulation of α1ß3Î³2 GABA_A receptors expressed in X. laevis oocytes using a propofol photoswitch tethered to the transmembrane helix.

Borghese, Cecilia M; Wang, Hua-Yu L; McHardy, Stanton F; Messing, Robert O; Trudell, James R; Harris, R Adron; Bertaccini, Edward J.

Proc Natl Acad Sci U S A ; 118(8)2021 Feb 23.

Artigo em Inglês | MEDLINE | ID: mdl-33593898

11.

De Novo Variants in CDK19 Are Associated with a Syndrome Involving Intellectual Disability and Epileptic Encephalopathy.

Chung, Hyung-Lok; Mao, Xiao; Wang, Hua; Park, Ye-Jin; Marcogliese, Paul C; Rosenfeld, Jill A; Burrage, Lindsay C; Liu, Pengfei; Murdock, David R; Yamamoto, Shinya; Wangler, Michael F; Chao, Hsiao-Tuan; Long, Hongyu; Feng, Li; Bacino, Carlos A; Bellen, Hugo J; Xiao, Bo.

Am J Hum Genet ; 106(5): 717-725, 2020 05 07.

Artigo em Inglês | MEDLINE | ID: mdl-32330417

12.

Imaginal disc growth factor maintains cuticle structure and controls melanization in the spot pattern formation of Bombyx mori.

Gao, Yun; Liu, Yun-Cai; Jia, Shun-Ze; Liang, Yan-Ting; Tang, Yu; Xu, Yu-Song; Kawasaki, Hideki; Wang, Hua-Bing.

PLoS Genet ; 16(9): e1008980, 2020 09.

Artigo em Inglês | MEDLINE | ID: mdl-32986708

13.

Activating KRAS, NRAS, and BRAF mutants enhance proteasome capacity and reduce endoplasmic reticulum stress in multiple myeloma.

Shirazi, Fazal; Jones, Richard J; Singh, Ram K; Zou, Jianxuan; Kuiatse, Isere; Berkova, Zuzana; Wang, Hua; Lee, Hans C; Hong, Samuel; Dick, Larry; Chattopadhyay, Nibedita; Orlowski, Robert Z.

Proc Natl Acad Sci U S A ; 117(33): 20004-20014, 2020 08 18.

Artigo em Inglês | MEDLINE | ID: mdl-32747568

14.

Variants in CAPZA2, a member of an F-actin capping complex, cause intellectual disability and developmental delay.

Huang, Yan; Mao, Xiao; van Jaarsveld, Richard H; Shu, Li; Terhal, Paulien A; Jia, Zhengjun; Xi, Hui; Peng, Ying; Yan, Huiming; Yuan, Shan; Li, Qibin; Wang, Hua; Bellen, Hugo J.

Hum Mol Genet ; 29(9): 1537-1546, 2020 Jun 03.

Artigo em Inglês | MEDLINE | ID: mdl-32338762

15.

Phonics training for English-speaking poor readers.

McArthur, Genevieve; Eve, Philippa M; Jones, Kristy; Banales, Erin; Kohnen, Saskia; Anandakumar, Thushara; Larsen, Linda; Marinus, Eva; Wang, Hua-Chen; Castles, Anne.

Cochrane Database Syst Rev ; 12: CD009115, 2012 Dec 12.

Artigo em Inglês | MEDLINE | ID: mdl-23235670

16.

An essential bifunctional enzyme in Mycobacterium tuberculosis for itaconate dissimilation and leucine catabolism.

Wang, Hua; Fedorov, Alexander A; Fedorov, Elena V; Hunt, Debbie M; Rodgers, Angela; Douglas, Holly L; Garza-Garcia, Acely; Bonanno, Jeffrey B; Almo, Steven C; de Carvalho, Luiz Pedro Sório.

Proc Natl Acad Sci U S A ; 116(32): 15907-15913, 2019 08 06.

Artigo em Inglês | MEDLINE | ID: mdl-31320588

17.

Telomere dysfunction impairs epidermal stem cell specification and differentiation by disrupting BMP/pSmad/P63 signaling.

Liu, Na; Yin, Yu; Wang, Haiying; Zhou, Zhongcheng; Sheng, Xiaoyan; Fu, Haifeng; Guo, Renpeng; Wang, Hua; Yang, Jiao; Gong, Peng; Ning, Wen; Ju, Zhenyu; Liu, Yifei; Liu, Lin.

PLoS Genet ; 15(9): e1008368, 2019 09.

Artigo em Inglês | MEDLINE | ID: mdl-31518356

18.

Interfacial Superconductivity Achieved in Parent AEFe₂As₂ (AE = Ca, Sr, Ba) by a Simple and Realistic Annealing Route.

Huyan, Shuyuan; Lyu, Yanfeng; Wang, Hua; Deng, Liangzi; Wu, Zheng; Lv, Bing; Zhao, Kui; Tian, Fei; Gao, Guanhui; Liu, Rui-Zhe; Ma, Xiaojing; Tang, Zhongjia; Gooch, Melissa; Chen, Shuo; Ren, Zhifeng; Qian, Xiaofeng; Chu, Ching-Wu.

Nano Lett ; 2021 Mar 01.

Artigo em Inglês | MEDLINE | ID: mdl-33646790

19.

Enhanced Superconductivity in Monolayer T_d-MoTe₂.

Rhodes, Daniel A; Jindal, Apoorv; Yuan, Noah F Q; Jung, Younghun; Antony, Abhinandan; Wang, Hua; Kim, Bumho; Chiu, Yu-Che; Taniguchi, Takashi; Watanabe, Kenji; Barmak, Katayun; Balicas, Luis; Dean, Cory R; Qian, Xiaofeng; Fu, Liang; Pasupathy, Abhay N; Hone, James.

Nano Lett ; 2021 Mar 09.

Artigo em Inglês | MEDLINE | ID: mdl-33689385

20.

GHR is involved in gastric cell growth and apoptosis via PI3K/AKT signalling.

Yan, Hong-Zhu; Wang, Hua-Feng; Yin, Yueling; Zou, Jue; Xiao, Feng; Yi, Li-Na; He, Ying; He, Bo-Sheng.

J Cell Mol Med ; 25(5): 2450-2458, 2021 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-33492754

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Inadequate DNA Damage Repair Promotes Mammary Transdifferentiation, Leading to BRCA1 Breast Cancer.

Structures of DPAGT1 Explain Glycosylation Disease Mechanisms and Advance TB Antibiotic Design.

PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1⁺CD38^hi cells and anti-PD-1 resistance.

Author Correction: PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1⁺CD38^hi cells and anti-PD-1 resistance.

Blockade of the checkpoint receptor TIGIT prevents NK cell exhaustion and elicits potent anti-tumor immunity.

Phonics training for English-speaking poor readers.

Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma.

BRCA1/FANCD2/BRG1-Driven DNA Repair Stabilizes the Differentiation State of Human Mammary Epithelial Cells.

The receptor-like kinases BAM1 and BAM2 are required for root xylem patterning.

Modulation of α1ß3Î³2 GABA_A receptors expressed in X. laevis oocytes using a propofol photoswitch tethered to the transmembrane helix.

De Novo Variants in CDK19 Are Associated with a Syndrome Involving Intellectual Disability and Epileptic Encephalopathy.

Imaginal disc growth factor maintains cuticle structure and controls melanization in the spot pattern formation of Bombyx mori.

Activating KRAS, NRAS, and BRAF mutants enhance proteasome capacity and reduce endoplasmic reticulum stress in multiple myeloma.

Variants in CAPZA2, a member of an F-actin capping complex, cause intellectual disability and developmental delay.

Phonics training for English-speaking poor readers.

An essential bifunctional enzyme in Mycobacterium tuberculosis for itaconate dissimilation and leucine catabolism.

Telomere dysfunction impairs epidermal stem cell specification and differentiation by disrupting BMP/pSmad/P63 signaling.

Interfacial Superconductivity Achieved in Parent AEFe₂As₂ (AE = Ca, Sr, Ba) by a Simple and Realistic Annealing Route.

Enhanced Superconductivity in Monolayer T_d-MoTe₂.

GHR is involved in gastric cell growth and apoptosis via PI3K/AKT signalling.