Detalhe da pesquisa
1.
Parkinson's disease-risk protein TMEM175 is a proton-activated proton channel in lysosomes.
Cell
; 185(13): 2292-2308.e20, 2022 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35750034
2.
Extracellular pH sensing by plant cell-surface peptide-receptor complexes.
Cell
; 185(18): 3341-3355.e13, 2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35998629
3.
Strain-level fitness in the gut microbiome is an emergent property of glycans and a single metabolite.
Cell
; 185(3): 513-529.e21, 2022 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35120663
4.
Carnosine regulation of intracellular pH homeostasis promotes lysosome-dependent tumor immunoevasion.
Nat Immunol
; 25(3): 483-495, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38177283
5.
Pan-ebolavirus protective therapy by two multifunctional human antibodies.
Cell
; 184(22): 5593-5607.e18, 2021 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34715022
6.
Therapeutic alphavirus cross-reactive E1 human antibodies inhibit viral egress.
Cell
; 184(17): 4430-4446.e22, 2021 08 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34416147
7.
Assembly Mechanism of Mucin and von Willebrand Factor Polymers.
Cell
; 183(3): 717-729.e16, 2020 10 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33031746
8.
Extracellular DNA Promotes Efficient Extracellular Electron Transfer by Pyocyanin in Pseudomonas aeruginosa Biofilms.
Cell
; 182(4): 919-932.e19, 2020 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32763156
9.
pH-Gated Succinate Secretion Regulates Muscle Remodeling in Response to Exercise.
Cell
; 183(1): 62-75.e17, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32946811
10.
Structural Basis of Low-pH-Dependent Lysosomal Cholesterol Egress by NPC1 and NPC2.
Cell
; 182(1): 98-111.e18, 2020 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32544384
11.
pH sensing controls tissue inflammation by modulating cellular metabolism and endo-lysosomal function of immune cells.
Nat Immunol
; 23(7): 1063-1075, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35668320
12.
Dual Sensing of Physiologic pH and Calcium by EFCAB9 Regulates Sperm Motility.
Cell
; 177(6): 1480-1494.e19, 2019 05 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31056283
13.
Direct Visualization of the Conformational Dynamics of Single Influenza Hemagglutinin Trimers.
Cell
; 174(4): 926-937.e12, 2018 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29961575
14.
Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor.
Cell
; 175(6): 1520-1532.e15, 2018 11 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-30500536
15.
GPR68 Senses Flow and Is Essential for Vascular Physiology.
Cell
; 173(3): 762-775.e16, 2018 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29677517
16.
Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR.
Cell
; 174(1): 72-87.e32, 2018 06 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-29861175
17.
TCR signaling promotes formation of an STS1-Cbl-b complex with pH-sensitive phosphatase activity that suppresses T cell function in acidic environments.
Immunity
; 56(12): 2682-2698.e9, 2023 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38091950
18.
Stress-Triggered Phase Separation Is an Adaptive, Evolutionarily Tuned Response.
Cell
; 168(6): 1028-1040.e19, 2017 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28283059
19.
Carnosine helps cancer cells to evade immune surveillance by regulating intracellular pH.
Nat Immunol
; 25(3): 399-400, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38273179
20.
Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel.
Mol Cell
; 83(14): 2524-2539.e7, 2023 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37390818