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1.
BMC Vet Res ; 20(1): 160, 2024 Apr 26.
Artigo em Inglês | MEDLINE | ID: mdl-38671452

RESUMO

BACKGROUND: Ventricular bigeminy due to myocardial ischemia has been reported in humans as well as in canine patients with obstructive gastrointestinal diseases. This is the first case report of ventricular bigeminy in a dog with a colonic torsion that resolved after fluid resuscitation and restoration of myocardial perfusion. CASE PRESENTATION: An 11-year-old, male neutered mixed breed dog presented with a one day history of vomiting, tenesmus, and lethargy. Physical examination identified an irregular heart rhythm and intermittent pulse deficits. A ventricular arrhythmia represented by ventricular premature complexes (VPCs) organized in bigeminy, was appreciated on a 3-lead electrocardiogram (ECG) with a single lead (II) view. Abdominal radiographs confirmed a colonic torsion. Prior to anesthetic induction, ventricular bigeminy was non responsive to fentanyl or lidocaine. The patient was anesthetized and intravascular volume deficit was identified by dampened plethysmographic wave amplitude (plethysomographic variability), audible softening of the Doppler sound, and more pronounced pulse deficits. Fluid resuscitation was achieved with a combination of intravenous crystalloid and colloid fluid therapy comprising 7.2% hypertonic saline and 6% hetastarch. The patient's cardiac rhythm converted to normal sinus after fluid resuscitation. The colonic torsion was surgically corrected. The patient recovered well from anesthesia and was ultimately discharged from the hospital 5 days later. CONCLUSIONS: The present case report highlights that myocardial ischemia can lead to ventricular arrythmias, such as ventricular bigeminy. This is the first documented case of ventricular bigeminy in the canine patient with a colonic torsion. Assessment of patient volume status and appropriate fluid resuscitation along with continuous electrocardiogram (ECG) monitoring are vital to patient stability under general anesthesia.


Assuntos
Doenças do Cão , Hidratação , Isquemia Miocárdica , Cães , Animais , Masculino , Doenças do Cão/terapia , Hidratação/veterinária , Isquemia Miocárdica/veterinária , Doenças do Colo/veterinária , Doenças do Colo/terapia , Doenças do Colo/etiologia , Eletrocardiografia/veterinária , Complexos Ventriculares Prematuros/veterinária , Complexos Ventriculares Prematuros/etiologia , Complexos Ventriculares Prematuros/terapia , Anormalidade Torcional/veterinária
2.
Vet Pathol ; 58(3): 574-577, 2021 05.
Artigo em Inglês | MEDLINE | ID: mdl-33590812

RESUMO

Melanosis coli is a well-described condition in humans, characterized by the accumulation of lipofuscin-laden macrophages in the lamina propria of the colon, giving it a dark tone. An increased apoptosis rate of colonic epithelial cells appears to be the underlying pathogenesis. In pigs, oxidative damage has been proposed as one of the causes for melanosis coli. In this article, we report a series of cases of melanosis coli in pigs affecting several finishing units in the south of Spain. Large intestines had dark green to brown pigmentation of the mucosa. Histological, histochemical, and ultrastructural studies confirmed a high number of lipofuscin-laden macrophages in the lamina propria of the rectum and colon, which additionally stained positive for the apoptosis marker cleaved caspase-3. Of note, all affected finishing units utilized water supply with a high content of sulfates, which may be one of the causes for melanosis coli development in pigs.


Assuntos
Doenças do Colo , Água Potável , Melanose , Doenças dos Suínos , Animais , Doenças do Colo/veterinária , Melanose/veterinária , Sulfatos , Suínos
3.
J Aquat Anim Health ; 33(1): 17-23, 2021 03.
Artigo em Inglês | MEDLINE | ID: mdl-33713491

RESUMO

Reports of intussusception in sea turtles are generally linked to marine debris ingestion; therefore, only a few cases of the disease are associated with parasitic infestations. The objective of this study was to describe the necropsy findings of the first reported case of colocolic intussusception in a green sea turtle Chelonia mydas, associated with the helminth Octangium sp. A juvenile female green sea turtle, which was registered and rescued by the team from the Cetaceans Project of Costa Branca, State University of Rio Grande do Norte, was examined. The animal died 1 d after being treated and was immediately submitted for necropsy. Our findings indicated that parasitic infestation by Octangium sp. in the green sea turtle caused intussusception and consequently led to the animal's death. Early diagnosis and surgical correction are fundamental for a good prognosis and, consequently, for successful rehabilitation of marine species.


Assuntos
Doenças do Colo/veterinária , Intussuscepção/veterinária , Trematódeos/isolamento & purificação , Infecções por Trematódeos/veterinária , Tartarugas , Animais , Brasil , Doenças do Colo/diagnóstico , Doenças do Colo/diagnóstico por imagem , Doenças do Colo/parasitologia , Doenças Funcionais do Colo , Feminino , Doenças do Colo Sigmoide , Infecções por Trematódeos/diagnóstico , Infecções por Trematódeos/diagnóstico por imagem , Infecções por Trematódeos/parasitologia
4.
Vet Radiol Ultrasound ; 61(2): 190-196, 2020 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-31837190

RESUMO

Colonic torsion is a life-threatening condition that results in colonic ischemia, necrosis, perforation, sepsis, and eventual death. The aim of this multicenter, retrospective case series study was to describe the CT findings in dogs with surgically confirmed colonic torsion. Medical records were searched for dogs with surgically confirmed colonic torsion following abdominal CT. Five dogs met the inclusion criteria. Three had a history of chronic intermittent diarrhea prior to presentation. Two dogs presented with acute vomiting, diarrhea, and abdominal pain and one dog presented with acute vomiting and lethargy. Computed tomographic findings in all dogs with surgically confirmed colonic torsion include: "whirl sign," displacement and distension of the cecum and colon, focal narrowing of the colon, and distension of the mesenteric vasculature in all dogs (5/5); streaky peritoneal fat and peritoneal effusion (4/5), pneumatosis coli (2/5), small intestinal distension (2/5), portal vein thrombosis (1/5), and reduced colonic wall contrast enhancement (1/5). In all dogs (5/5), the torsion site was the descending colon and demonstrated an anticlockwise rotation. At surgery, three of the five dogs had a partial colonic torsion with hyperemia at the site of obstruction and two of the five dogs had a complete torsion with marked necrosis of the colonic wall. Displacement of the colon and cecum, segmental distension and focal narrowing of the colon, the presence of a "whirl sign" and distension of the mesenteric vasculature are CT findings highly suggestive of colonic torsion.


Assuntos
Doenças do Colo/veterinária , Doenças do Cão/diagnóstico por imagem , Volvo Intestinal/veterinária , Tomografia Computadorizada por Raios X/veterinária , Anormalidade Torcional/veterinária , Animais , Colo/diagnóstico por imagem , Colo/patologia , Doenças do Colo/diagnóstico por imagem , Doenças do Colo/patologia , Cães , Feminino , Volvo Intestinal/diagnóstico por imagem , Volvo Intestinal/patologia , Masculino , Estudos Retrospectivos , Anormalidade Torcional/diagnóstico por imagem , Anormalidade Torcional/patologia
5.
BMC Vet Res ; 15(1): 468, 2019 Dec 21.
Artigo em Inglês | MEDLINE | ID: mdl-31864369

RESUMO

BACKGROUND: Horses that undergo surgery for treatment of primary large colon disease have been reported to be at increased risk of developing recurrent colic episodes postoperatively. The reasons for this are currently unknown. The aim of the current study was to characterise the faecal microbiota of horses with colic signs associated with primary large colon lesions treated surgically and to compare the composition of their faecal microbiota to that of a control group of horses undergoing emergency orthopaedic treatment. Faecal samples were collected from horses in both groups on admission to hospital, during hospitalisation and following discharge from hospital for a total duration of 12 weeks. Additionally, colonic content samples were collected from surgical colic patients if pelvic flexure enterotomy was performed during laparotomy. A total of 12 samples were collected per horse. DNA was extracted from samples using a commercial kit. Amplicon mixtures were created by PCR amplification of the V1 - V2 regions of the bacterial 16S rRNA genes and submitted for sequencing using the Ion Torrent PGM next-generation sequencing system. Multivariate data analysis was used to characterise the faecal microbiota and to investigate differences between groups. RESULTS: Reduced species richness was evident in the colonic samples of the colic group compared to concurrent sampling of the faeces. Alpha and beta diversity differed significantly between the faecal and colonic microbiota with 304 significantly differentially abundant OTUs identified. Only 46 OTUs varied significantly between the colic and control group. There were no significant differences in alpha and beta diversity of faecal microbiota between colic and control horses at admission. However, this lack of significant differences between groups should be interpreted with caution due to a small sample size. CONCLUSIONS: The results of the current study suggest that faecal samples collected at hospital admission in colic cases may not accurately represent changes in upper gut microbiota in horses with colic due to large colon disease.


Assuntos
Cólica/veterinária , Doenças do Colo/veterinária , Fezes/microbiologia , Microbioma Gastrointestinal , Doenças dos Cavalos/cirurgia , Animais , Cólica/microbiologia , Cólica/cirurgia , Doenças do Colo/microbiologia , Doenças do Colo/cirurgia , Doenças dos Cavalos/microbiologia , Cavalos , RNA Ribossômico 16S/análise
6.
Can Vet J ; 60(9): 991-994, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31523088

RESUMO

This case report documents an unusual case of persistent colic in a horse caused by an anomalous vascularized band of tissue running between the visceral surface of the liver and the mesentery of the large colon at the level of the sternal/diaphragmatic flexures. The horse was presented with a history of exhibiting signs of mild persistent colic that were suspected to be caused by displacement of the large colon. Volvulus of the large colon was identified during exploratory celiotomy. The band of tissue was transected, and the displacement corrected. The horse made an uneventful recovery.


Traitement chirurgical de coliques persistantes chez un cheval causées par une bande fibreuse vasculaire anormale. Ce rapport de cas documente un cas inhabituel de coliques persistantes chez un cheval causées par une bande de tissue fibreux et vasculaire anormale qui se trouvait entre la face viscérale du foie et le mésentère du gros colon au niveau des courbures sternale et diaphragmatique. L'anamnèse incluait des signes faibles de colique qui étaient soupçonnés d'être reliés à un déplacement de colon. Un volvulus du gros colon a été identifié pendant une laparotomie. La bande de tissue fut coupée et le déplacement de colon corrigé. La récupération postopératoire du cheval fut sans complications.(Traduit par Dre Marie-Soleil Dubois).


Assuntos
Cólica/veterinária , Doenças do Colo/veterinária , Doenças dos Cavalos , Volvo Intestinal/veterinária , Animais , Cavalos
7.
Can Vet J ; 60(4): 381-385, 2019 04.
Artigo em Inglês | MEDLINE | ID: mdl-30992593

RESUMO

This study compared post-operative complications and survival in horses with right dorsal displacement of the large colon (RDD) and horses with other non-strangulating large colon (NSLC) lesions. Data were obtained from medical records of horses undergoing exploratory laparotomy from 2000 to 2016 and from owner questionnaire. Of 137 horses that fitted the inclusion criteria, 67 (49%) had RDD and 70 (51%) had NSLC lesions. Twenty-eight horses with RDD (42%) and 27 horses with NSLC (39%) experienced ≥ 1 complication after surgery. The RDD group showed more severe complications than the NSLC group (P = 0.0145). Horses with RDD were more likely to develop colic in the short term (P = 0.0111), but not in the long-term (P = 0.453), and were more likely to have a 2nd laparotomy (P = 0.0003). There was no significant difference in short- or long-term survival between groups. Major post-operative complications in the RDD group did not influence short- or long-term survival.


Complications et survie des chevaux atteints d'un déplacement dorsal droit du gros côlon confirmé par chirurgie. Cette étude a comparé les complications et la survie postopératoires chez les chevaux atteints d'un déplacement dorsal droit du gros côlon (DDD) et les chevaux atteints d'autres lésions non étranglantes du gros côlon (LNEGC). Des données ont été obtenues dans les dossiers médicaux de chevaux qui avaient subi une laparatomie exploratoire entre 2000 et 2016 et dans un questionnaire auprès des propriétaires. Parmi les 137 chevaux qui satisfaisaient aux critères d'inclusion, 67 (49 %) avaient eu un DDD et 70 (51 %) avaient eu des lésions LNEGC. Vingt-huit chevaux atteints d'un DDD (42 %) et 27 chevaux qui avaient une LNEGC (39 %) ont éprouvé ≥ 1 complication après la chirurgie. Le groupe DDD a manifesté des complications plus graves que le groupe LNEGC (P = 0,0145). Il était plus probable que les chevaux atteints de DDD développent des coliques à court terme (P = 0,0111), mais pas à long terme (P = 0,453) et il était plus probable qu'ils aient à subir une deuxième laparotomie (P = 0,0003). Il n'y avait aucune différence significative au niveau de la survie à court ou à long terme entre les groupes. Les complications postopératoires majeures du groupe DDD n'ont pas influencé la survie à court ou à long terme.(Traduit par Isabelle Vallières).


Assuntos
Cólica/veterinária , Doenças do Colo/veterinária , Doenças dos Cavalos , Animais , Cavalos , Complicações Pós-Operatórias/veterinária , Estudos Retrospectivos
8.
Vet Surg ; 47(4): 490-498, 2018 May.
Artigo em Inglês | MEDLINE | ID: mdl-29626348

RESUMO

OBJECTIVE: To describe a technique for colopexy via a left ventral paramedian incision and report postoperative clinical outcomes. STUDY DESIGN: Retrospective case series. ANIMALS: One hundred fifty-six thoroughbred broodmares treated with a colopexy through a left ventral paramedian incision between 1999 and 2015. METHODS: Medical records were reviewed for postoperative complications and survival to discharge. The survival rate at 1 year after surgery was based on the medical record, progeny record, or client telephone conversation. Progeny records were reviewed to assess reproductive performance. T tests, χ2 tests, logistic regression, and Kaplan-Meier survival curves were used to identify prognostic factors. RESULTS: The rates of postoperative recurrence of large colon volvulus and colon rupture were 1.2% and 3%, respectively. Ninety-three percent of mares that were treated were discharged alive from the hospital, and 78% were alive 1 year after surgery. The diagnosis of 1 of the following complications increased the risk of death within 1 year: systemic inflammatory response syndrome (SIRS), diarrhea, and/or thrombophlebitis (odds ratio [OR] 4.76). Sixty-six percent of mares that were pregnant at the time of colopexy and discharged alive from the hospital produced a live foal. The percentage of live foals produced each year that the mare was bred after colopexy was 67%. CONCLUSION: Thoroughbred mares treated with colopexy via a left paramedian incision had a good prognosis for survival and continued use as a broodmare. SIRS, diarrhea, or jugular thrombophlebitis affected long-term survival in this population. CLINICAL SIGNIFICANCE: Colopexy via a left paramedian incision is a suitable alternative to colopexies requiring a second incision or creating adhesions between the colon and the linea alba in thoroughbred mares.


Assuntos
Doenças do Colo/veterinária , Procedimentos Cirúrgicos do Sistema Digestório/veterinária , Doenças dos Cavalos/cirurgia , Volvo Intestinal/veterinária , Complicações Pós-Operatórias/veterinária , Animais , Procedimentos Cirúrgicos do Sistema Digestório/efeitos adversos , Procedimentos Cirúrgicos do Sistema Digestório/métodos , Feminino , Cavalos , Volvo Intestinal/cirurgia , Prontuários Médicos , Gravidez , Recidiva , Estudos Retrospectivos , Taxa de Sobrevida
9.
Vet Anaesth Analg ; 45(6): 876-880, 2018 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-30297131

RESUMO

OBJECTIVE: To investigate the pharmacological profile and side effects of buprenorphine administered as a sustained-release formulation in horses. STUDY DESIGN: Pilot trial. ANIMALS: A total of four experimental horses, aged 18-27 years and weighing 508-578 kg. METHODS: Buprenorphine (0.1 mg kg-1) was mixed as a freshly prepared sterile solution with a sustained-release drug carrier. It was administered by the subcutaneous (n = 2) or intramuscular (n = 2) route. During the experiment, the horses were closely monitored, equipped with a step counter and blood samples were collected for quantification of buprenorphine in plasma. RESULTS: All four horses developed colon constipation requiring medical therapy, together with increased locomotor activity. One horse, requiring surgical treatment of colon constipation, was euthanized during recovery from anaesthesia for weakness and severe lower airway obstruction. The three other horses recovered fully within 5-7 days. Plasma buprenorphine concentrations were between 1 and 8 ng mL-1 for approximately 48 hours. No local reaction was observed at the injection sites. CONCLUSIONS AND CLINICAL RELEVANCE: Administration of the sustained-release formulation of buprenorphine at a dose of 0.1 mg kg-1 resulted in plasma concentrations compatible with antinociceptive activity for at least 48 hours. The observed severe and undesirable effects of colon constipation and increased locomotor activity definitely preclude clinical use of sustained-release buprenorphine at this dose.


Assuntos
Analgésicos Opioides/efeitos adversos , Buprenorfina/efeitos adversos , Doenças do Colo/veterinária , Constipação Intestinal/veterinária , Doenças dos Cavalos/induzido quimicamente , Animais , Doenças do Colo/induzido quimicamente , Constipação Intestinal/induzido quimicamente , Preparações de Ação Retardada/efeitos adversos , Cavalos , Projetos Piloto
10.
Vet Surg ; 45(S1): O60-O69, 2016 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-27623215

RESUMO

OBJECTIVES: 1) To identify factors associated with short-term survival and time to death after hospital discharge in horses with nephrosplenic entrapment (NSE). 2) To compare the frequency of recurrent colic episodes in horses with and without laparoscopic closure of the nephrosplenic space. STUDY DESIGN: Historical cohort with a nested case control. ANIMALS: Client-owned horses. METHODS: Medical records of horses treated for NSE from January 1, 2002 to June 1, 2014 were reviewed. Data collected included signalment, physical examination parameters, laboratory results, diagnostic findings, and treatments. Factors associated with short-term survival to discharge were analyzed with a multivariable logistic regression model and time to death after hospital discharge was analyzed with a Cox proportional hazards model. RESULTS: During the study period, 211 horses had 231 NSE events and 192/211 (91%) horses survived to discharge. A positive difference in packed cell volume (PCV at admission - PCV after treatment) was associated with reduced odds of nonsurvival with each increment (OR: 0.899, 95% CI 0.816-0.991, P=.03) while the presence of concurrent alimentary lesions (OR: 8.47, 95% CI 1.42-50.4, P=.02) were significantly associated with increased odds of nonsurvival in the short term. Of 156 horses that survived to discharge for which follow-up was available, 152 (97%) were alive for ≥1 year. Increasing age (incremental years) at hospital admission was significantly associated with death after discharge (hazard ratio 1.078, 95% CI 1.002-1.16, P=.049). Recurrence of NSE was documented in 49/211 (23%) horses. The overall change in colic score indicated a reduction in colic in horses following laparoscopic closure of the nephrosplenic space compared with horses that did not have closure of the nephrosplenic space (P<0.001). CONCLUSION: An increase in PCV from admission to after treatment and concurrent abdominal lesions were associated with increased odds of nonsurvival to discharge in horses with NSE. Horses that underwent laparoscopic closure had reduced colic episodes compared with horses without laparoscopic closure.


Assuntos
Cólica/veterinária , Doenças do Colo/veterinária , Doenças dos Cavalos/cirurgia , Laparoscopia/veterinária , Animais , Cólica/cirurgia , Doenças do Colo/cirurgia , Feminino , Cavalos , Laparoscopia/métodos , Masculino , Recidiva , Estudos Retrospectivos
11.
Vet Surg ; 45(6): 824-30, 2016 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-27410676

RESUMO

OBJECTIVE: To evaluate use of a knotless suture for laparoscopic closure of the equine nephrosplenic space. STUDY DESIGN: Experimental in vivo study. ANIMALS: Normal horses without previous history of abdominal surgery (n=8). METHODS: The nephrosplenic space was closed under laparoscopic visualization using a unidirectional, barbed 0 metric absorbable suture (copolymer of glycolic acid and trimethylene carbonate). Intracorporeal suturing of the nephrosplenic space was performed in a cranial-to-caudal direction in a simple continuous fashion. Repeat evaluation was performed laparoscopically in 2 horses and by necropsy in 6 horses. The length of closure was measured and nature of the healed tissue was evaluate grossly. RESULTS: Total surgery time was 65-167 minutes (mean ± SD, 89.6 ± 22.6). Suturing time was 30-65 minutes (40.4 ± 16.3). Second laparoscopy in 2 horses was performed at days 198 and 227. Necropsy was performed at day 69-229 postoperatively (132.7 ± 63.0) in 6 horses. The closure measured 12-14 cm in length (13 ± 1) and consisted of mature fibrous tissue bridging the splenic capsule and the nephrosplenic ligament. No residual suture material was identified grossly in any horses. The procedure was easily performed; extracorporeal suture management to hold it taut was unnecessary since the barbs had excellent purchase in the apposed tissues, and intracorporeal knot tying was not required. CONCLUSION: The barbed knotless suture appears to be a valid alternative to facilitate laparoscopic closure of the nephrosplenic space in normal horses; however, further work is necessary to investigate its suitability in clinically affected horses.


Assuntos
Doenças dos Cavalos/cirurgia , Laparoscopia/veterinária , Técnicas de Sutura/veterinária , Suturas/veterinária , Animais , Fenômenos Biomecânicos , Doenças do Colo/prevenção & controle , Doenças do Colo/cirurgia , Doenças do Colo/veterinária , Doenças dos Cavalos/prevenção & controle , Cavalos
12.
Vet Pathol ; 52(4): 663-7, 2015 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-25421421

RESUMO

Melanosis coli is a dark discoloration of the colon due to accumulation of pigment-laden macrophages in the lamina propria. Three case submissions were received where rectal discoloration was reported at slaughter in pigs from separate production systems and melanosis coli was confirmed microscopically. Tissues from affected and unaffected cohort pigs were evaluated for evidence of oxidative damage using immunohistochemical staining for 3-nitrotyrosine, 4-hyroxynonenol, and malondialdehyde. Affected colons had significantly greater immunolabeling for all 3 target compounds than unaffected colons (P ≤ .001, all analyses). Hepatic vitamin E levels were low in both affected and unaffected pigs, and there was a trend toward lower values in affected pigs. Given the limited number of slaughter-collected samples available for this investigation, further study is warranted to elucidate the possible association between low vitamin E concentrations and oxidative damage in cases of melanosis coli in pigs.


Assuntos
Doenças do Colo/veterinária , Melanose/veterinária , Aldeídos/metabolismo , Animais , Colo/patologia , Doenças do Colo/patologia , Feminino , Macrófagos/patologia , Malondialdeído/metabolismo , Melanose/patologia , Estresse Oxidativo , Suínos , Tirosina/análogos & derivados , Tirosina/metabolismo
13.
Vet Radiol Ultrasound ; 56(6): 666-9, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26180007

RESUMO

The muscularis layer of the canine colon has been reported to appear homogeneously hypoechoic on ultrasonography. A hyperechoic band in the muscularis layer paralleling the serosal surface has been observed by authors in routine canine abdominal ultrasound examinations. The purpose of this prospective and retrospective cross-sectional study was to determine the prevalence of this lesion, characterize its ultrasonographic and postmortem histologic features, and correlate its presence with clinical signs of gastrointestinal disease. In the prospective study, all dogs that underwent routine abdominal ultrasonography by one of two observers during a 4-week period were included without any exclusion criteria. One observer reviewed ultrasound images and recorded the presence or absence of this lesion and its distribution, e.g. focal (< 2 cm long) or diffuse (> 2 cm long). In the retrospective study, all dogs that had both abdominal ultrasonography and necropsy from January 2011 to December 2013 were included without any exclusion criteria. Histologic examinations were performed by two observers and Masson's trichrome stain was used to identify fibrous collagen. Prevalence for the hyperechoic band was 32% in the prospective and 4.8% in the retrospective sample populations, respectively. The hyperechoic band appeared as diffuse, focal, or a combination of both. Histologic sections were available for six dogs. In a few cases, the lesion corresponded to the presence of fibrous tissue in the myenteric plexus or in the tunica muscularis. None of the dogs had a history of diarrhea. Findings supported the hypothesis that a colonic muscularis hyperechoic band paralleling the serosal layer in dogs could be a normal variant rather than a marker of disease.


Assuntos
Colo/diagnóstico por imagem , Cães/anatomia & histologia , Membrana Serosa/diagnóstico por imagem , Variação Anatômica , Animais , Colágeno/análise , Colágeno/ultraestrutura , Doenças do Colo/diagnóstico por imagem , Doenças do Colo/patologia , Doenças do Colo/veterinária , Estudos Transversais , Doenças do Cão/diagnóstico por imagem , Doenças do Cão/patologia , Mucosa Intestinal/diagnóstico por imagem , Músculo Liso/diagnóstico por imagem , Estudos Prospectivos , Estudos Retrospectivos , Ultrassonografia
14.
Can Vet J ; 56(11): 1177-80, 2015 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-26538675

RESUMO

A mature Quarter horse was euthanized following colic of 3 days duration. Postmortem, the large intestine, except the descending colon, was diffusely distended and associated with adhesion of the transverse colon to the pancreas, which had changes consistent with chronic active interstitial pancreatitis. Other lesions included hepatic fibrosis, erosive gastritis, and bilateral adrenal cortical hyperplasia.


Pancréatite interstitielle chronique active comme cause d'une obstruction du côlon transversal et de coliques chez un cheval. Un cheval Quarter horse adulte a été euthanasié après des coliques d'une durée de 3 jours. À l'autopsie, il a été observé que le gros intestin, sauf le côlon descendant, présentait une distension diffuse et était associé à l'adhésion du côlon transversal au pancréas qui indiquait des changements conformes à une pancréatite interstitielle chronique active. Les autres lésions incluaient une fibrose hépatique, une gastrite érosive et une hyperplasie corticale bilatérale des surrénales.(Traduit par Isabelle Vallières).


Assuntos
Cólica/veterinária , Doenças do Colo/veterinária , Doenças dos Cavalos/etiologia , Obstrução Intestinal/veterinária , Pancreatite/veterinária , Animais , Doença Crônica , Cólica/patologia , Doenças do Colo/patologia , Doenças dos Cavalos/patologia , Cavalos , Obstrução Intestinal/patologia , Masculino , Pancreatite/patologia
15.
Can Vet J ; 56(3): 240-4, 2015 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-25750442

RESUMO

An 8-year-old spayed female domestic shorthair cat was presented with a 4- to 5-month history of a progressively growing mass above her anus and an inability to defecate for 3 to 4 wk. External perianal and internal regional masses were subsequently identified and diagnosed as tumors of neuroendocrine origin through surgical excision and histopathologic evaluation. The cat was treated with 2 courses of chemotherapy and radiation therapy.


Tumeur neuroendocrinienne périanale avec une métastase suspectée des ganglions lymphatiques causant une compression du côlon et un mégacôlon subséquent. Une chatte commune domestique stérilisée âgée de 8 ans a été présentée avec une anamnèse de 4 ou 5 mois d'une masse à croissance progressive au-dessus de l'anus et l'incapacité de déféquer depuis 3 ou 4 semaines. Les masses périanales externes et régionales internes ont été subséquemment identifiées et diagnostiquées comme des tumeurs d'origine neuro-endocrinienne suite à l'excision chirurgicale et une évaluation histopathologique. La chatte a été traitée à l'aide de deux séries de traitement et d'une radiothérapie.(Traduit par Isabelle Vallières).


Assuntos
Neoplasias das Glândulas Anais/patologia , Carcinoma Neuroendócrino/veterinária , Doenças do Gato/patologia , Doenças do Colo/veterinária , Megacolo/veterinária , Neoplasias das Glândulas Anais/complicações , Neoplasias das Glândulas Anais/terapia , Animais , Antineoplásicos/uso terapêutico , Carcinoma Neuroendócrino/complicações , Carcinoma Neuroendócrino/patologia , Carcinoma Neuroendócrino/terapia , Doenças do Gato/etiologia , Doenças do Gato/terapia , Gatos , Doenças do Colo/complicações , Doenças do Colo/patologia , Feminino , Megacolo/etiologia , Megacolo/patologia , Radioterapia/veterinária
16.
Pol J Vet Sci ; 18(4): 793-8, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26812822

RESUMO

UNLABELLED: Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used in animals, especially in dogs, to manage pain due to inflammatory disease. This study investigated whether plant drugs can prevent mucosal injury induced by robenacoxib. We used fifteen healthy beagle dogs (7 male and 8 female) aged 4 months, weighing 4.2-5.1 kg at the beginning of the study. Endoscopy and biopsy of the colon were performed before and on the 21 day treatment with robenacoxib (1), robenacoxib, herbal solution with liquorice extract (2), placebo - an empty capsule (3). There were 5 animals in each group. The greatest microscopic damage in the colon was observed in animals which received robenacoxib. Plant drug administration reduced the severity of lesions in the colon when administered with robenacoxib (ARI = - 0.15). CONCLUSION: concurrent administration of liquorice extract and plant solution with robenacoxib was associated with significant decreased severity of the robenacoxib-induced colonic mucosal lesions.


Assuntos
Doenças do Colo/veterinária , Difenilamina/análogos & derivados , Doenças do Cão/induzido quimicamente , Glycyrrhiza/química , Fenilacetatos/efeitos adversos , Extratos Vegetais/farmacologia , Animais , Anti-Inflamatórios não Esteroides/efeitos adversos , Doenças do Colo/induzido quimicamente , Doenças do Colo/tratamento farmacológico , Difenilamina/efeitos adversos , Doenças do Cão/tratamento farmacológico , Cães , Feminino , Mucosa Intestinal/efeitos dos fármacos , Masculino , Extratos Vegetais/química
17.
J Med Primatol ; 43(6): 498-502, 2014 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-24930866

RESUMO

BACKGROUND: Diffuse nodular lymphoid hyperplasia (DNLH) of gastrointestinal tract is regarded as a very rare disease in the adult population. It is characterized by presence of diffuse detectable small polypoid masses distributed in the small intestine, colon, or both. METHODS: A 6-year-old male in captivity suddenly died, due to myocardial infarction. During routine necropsy procedure, incidentally, numerous tan, sessile polyps, up to 0.2 cm were noticed in all segments of the colon. RESULTS: Histopathological and immunohistochemical examination revealed polypoid masses as nodular lymphoid hyperplasia (NLH), comparable with DNLH of the colon in human. CONCLUSIONS: In this article, the author has tried to introduce some immunosuppresive (e.g., simian retrovirus type D (SRV), simian immunodeficiency virus (SIV)) and opportunistic viruses (e.g., lymphocryptovirus, γ-herpesvirus, adenovirus), as well as, primary and opportunistic bacteria (e.g., Yersinia psedotuberculosis, and Helicobacter spp.) that may trigger benign reactive process, lymphoid hyperplasia, in non-human primates (NHPs) in captivity.


Assuntos
Chlorocebus aethiops , Colo/patologia , Doenças do Colo/veterinária , Hiperplasia/veterinária , Doenças dos Macacos/patologia , Animais , Doenças do Colo/etiologia , Doenças do Colo/patologia , Hiperplasia/etiologia , Hiperplasia/patologia , Masculino , Doenças dos Macacos/etiologia
18.
BMC Vet Res ; 10 Suppl 1: S2, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-25238179

RESUMO

BACKGROUND: Large colon impactions are a common cause of colic in the horse. There are no scientific reports on the clinical presentation, diagnostic tests and treatments used in first opinion practice for large colon impaction cases. The aim of this study was to describe the presentation, diagnostic approach and treatment at the primary assessment of horses with large colon impactions. METHODS: Data were collected prospectively from veterinary practitioners on the primary assessment of equine colic cases over a 12 month period. Inclusion criteria were a diagnosis of primary large colon impaction and positive findings on rectal examination. Data recorded for each case included history, signalment, clinical and diagnostic findings, treatment on primary assessment and final case outcome. Case outcomes were categorised into three groups: simple medical (resolved with single treatment), complicated medical (resolved with multiple medical treatments) and critical (required surgery, were euthanased or died). Univariable analysis using one-way ANOVA and Tukey's post-hoc test, Kruskal Wallis with Dunn's post-hoc test and Chi squared analysis were used to compare between different outcome categories. RESULTS: 1032 colic cases were submitted by veterinary practitioners: 120 cases met the inclusion criteria for large colon impaction. Fifty three percent of cases were categorised as simple medical, 36.6% as complicated medical, and 9.2% as critical. Most cases (42.1%) occurred during the winter. Fifty nine percent of horses had had a recent change in management, 43% of horses were not ridden, and 12.5% had a recent / current musculoskeletal injury. Mean heart rate was 43 bpm (range 26-88) and most cases showed mild signs of pain (67.5%) and reduced gut sounds (76%). Heart rate was significantly increased and gut sounds significantly decreased in critical compared to simple medical cases (p<0.05). Fifty different treatment combinations were used, with NSAIDs (93%) and oral fluids (71%) being administered most often. CONCLUSIONS: Large colon impactions typically presented with mild signs of colic; heart rate and gut sounds were the most useful parameters to distinguish between simple and critical cases at the primary assessment. The findings of seasonal incidence and associated management factors are consistent with other studies. Veterinary practitioners currently use a wide range of different treatment combinations for large colon impactions.


Assuntos
Cólica/veterinária , Doenças do Colo/veterinária , Impacção Fecal/veterinária , Doenças dos Cavalos/diagnóstico , Médicos Veterinários , Animais , Cólica/diagnóstico , Cólica/terapia , Doenças do Colo/diagnóstico , Doenças do Colo/terapia , Coleta de Dados , Impacção Fecal/diagnóstico , Impacção Fecal/terapia , Doenças dos Cavalos/terapia , Cavalos , Humanos , Estações do Ano
19.
Vet Surg ; 43(7): 882-7, 2014 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-25088524

RESUMO

OBJECTIVE: To report a surgical technique for treatment of chronic, recurrent cloacal prolapse in a sulphur-crested cockatoo (Cacatua galerita). STUDY DESIGN: Clinical report ANIMALS: Sulphur-crested cockatoo (n = 1) METHODS: The bird was admitted with a 2-year history of periodic lethargy, decreased appetite, dyschezia, tenesmus, and colocloacal prolapse. An incisional colopexy was performed under general anesthesia to permanently reduce the colocloacal prolapse. To gain access to the coelomic cavity, a ventral U-shaped incision was made, after which the colon and cloaca were restored in their normal anatomic position. Subsequently, the distal colon was sutured to the left abdominal wall. RESULTS: Colocloacal prolapse was successfully reduced. One month later, cloacoplasty was performed to reduce cloacal width. Long-term follow-up, including a barium contrast study, revealed normal function and an intact colopexy, without recurrence of the prolapse. CONCLUSIONS: Incisional colopexy is feasible despite a bird's relative small body size.


Assuntos
Doenças das Aves/cirurgia , Cacatuas , Doenças do Colo/veterinária , Animais , Doenças das Aves/patologia , Doenças do Colo/cirurgia , Procedimentos Cirúrgicos do Sistema Digestório/veterinária , Masculino , Prolapso
20.
Vet Med Sci ; 10(4): e1481, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-39031749

RESUMO

In this case report, we present an unusual clockwise torsion of left colon around mesenteric root in a 10-month-old Arab filly, highlighting the clinical presentation, diagnostic approach and successful surgical intervention. A 10-month-old Arab filly weighing approximately 250 kg was referred with signs of acute abdominal pain. The history revealed anorexia, restlessness and severe abdominal pain that had begun the previous day. The local practitioner had previously administered flunixin meglumine, an analgesic, but it proved ineffective in relieving the pain. Upon physical examination, the filly exhibited sweating, a body temperature of 38.5°C, tachycardia (65 beats per minute) and tachypnea (25 breaths per minute). Due to the severity of the colic and the lack of response to the conservative treatments, surgical intervention was deemed necessary. An exploratory midline celiotomy was performed to evaluate the abdominal organs. During the examination, no obvious primary lesions were identified in the evaluated organs. However, a restriction in exteriorizing the left colon's length was observed. Further examination revealed an unusual clockwise torsion of the left colon that displaced in left to the right side around the mesenteric root; thereby, pelvic flexure was located in the normal anatomical position with a short length. To the best of our knowledge, this is the first reported case of clockwise torsion and an atypical displacement of the left colon in horses. The surgical correction of the displacement was successfully performed. The filly showed improvement post-surgery and did not exhibit any complications during the recovery period.


Assuntos
Doenças dos Cavalos , Animais , Doenças dos Cavalos/cirurgia , Doenças dos Cavalos/diagnóstico , Feminino , Cavalos , Anormalidade Torcional/veterinária , Anormalidade Torcional/cirurgia , Doenças do Colo/veterinária , Doenças do Colo/cirurgia , Colo/cirurgia , Colo/patologia
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