Detalhe da pesquisa
1.
Host and pathogen response to bacteriophage engineered against Mycobacterium abscessus lung infection.
Cell
; 185(11): 1860-1874.e12, 2022 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35568033
2.
Mechanism of CFTR correction by type I folding correctors.
Cell
; 185(1): 158-168.e11, 2022 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34995514
3.
A Therapy for Most with Cystic Fibrosis.
Cell
; 180(2): 211, 2020 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31978337
4.
A combination therapy for cystic fibrosis.
Cell
; 163(1): 17, 2015 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26406363
5.
CFTR function, pathology and pharmacology at single-molecule resolution.
Nature
; 616(7957): 606-614, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36949202
6.
High-content siRNA screen reveals global ENaC regulators and potential cystic fibrosis therapy targets.
Cell
; 154(6): 1390-400, 2013 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24034256
7.
Cystic Fibrosis Transmembrane Conductance Regulator Attaches Tumor Suppressor PTEN to the Membrane and Promotes Anti Pseudomonas aeruginosa Immunity.
Immunity
; 47(6): 1169-1181.e7, 2017 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29246444
8.
Heterogenous biofilm mass-transport model replicates periphery sequestration of antibiotics in Pseudomonas aeruginosa PAO1 microcolonies.
Proc Natl Acad Sci U S A
; 120(47): e2312995120, 2023 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37956290
9.
Cystic Fibrosis Modulator Therapies.
Annu Rev Med
; 74: 413-426, 2023 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35973718
10.
Druggable redox pathways against Mycobacterium abscessus in cystic fibrosis patient-derived airway organoids.
PLoS Pathog
; 19(8): e1011559, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37619220
11.
Elexacaftor/Tezacaftor/Ivacaftor Treatment and Depression-related Events.
Am J Respir Crit Care Med
; 209(3): 299-306, 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37890129
12.
Two rare variants that affect the same amino acid in CFTR have distinct responses to ivacaftor.
J Physiol
; 602(2): 333-354, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38186087
13.
Identification and characterization of aptameric inhibitors of human neutrophil elastase.
J Biol Chem
; 299(8): 104889, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37286041
14.
P. aeruginosa tRNA-fMet halves secreted in outer membrane vesicles suppress lung inflammation in cystic fibrosis.
Am J Physiol Lung Cell Mol Physiol
; 326(5): L574-L588, 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38440830
15.
CFTR corrector C17 is effective in muscular dystrophy, in vivo proof of concept in LGMDR3.
Hum Mol Genet
; 31(4): 499-509, 2022 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34505136
16.
Population pharmacokinetics and target attainment analysis of vancomycin after intermittent dosing in adults with cystic fibrosis.
Antimicrob Agents Chemother
; 68(1): e0099223, 2024 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38059634
17.
Mutations in genes lpxL1, bamA, and pmrB impair the susceptibility of cystic fibrosis strains of Pseudomonas aeruginosa to murepavadin.
Antimicrob Agents Chemother
; 68(1): e0129823, 2024 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38092672
18.
CFTR modulator therapy: transforming the landscape of clinical care in cystic fibrosis.
Lancet
; 402(10408): 1171-1184, 2023 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37699418
19.
Lipid-driven CFTR clustering is impaired in cystic fibrosis and restored by corrector drugs.
J Cell Sci
; 135(5)2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35060604
20.
Triple Therapy for Cystic Fibrosis Phe508del-Gating and -Residual Function Genotypes.
N Engl J Med
; 385(9): 815-825, 2021 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34437784