Pesquisa | Biblioteca Virtual em Saúde

1.

Complex effects of sequence variants on lipid levels and coronary artery disease.

Snaebjarnarson, Audunn S; Helgadottir, Anna; Arnadottir, Gudny A; Ivarsdottir, Erna V; Thorleifsson, Gudmar; Ferkingstad, Egil; Einarsson, Gudmundur; Sveinbjornsson, Gardar; Thorgeirsson, Thorgeir E; Ulfarsson, Magnus O; Halldorsson, Bjarni V; Olafsson, Isleifur; Erikstrup, Christian; Pedersen, Ole B; Nyegaard, Mette; Bruun, Mie T; Ullum, Henrik; Brunak, Søren; Iversen, Kasper Karmark; Christensen, Alex Hoerby; Olesen, Morten S; Ghouse, Jonas; Banasik, Karina; Knowlton, Kirk U; Arnar, David O; Thorgeirsson, Gudmundur; Nadauld, Lincoln; Ostrowski, Sisse Rye; Bundgaard, Henning; Holm, Hilma; Sulem, Patrick; Stefansson, Kari; Gudbjartsson, Daniel F.

Cell ; 186(19): 4085-4099.e15, 2023 09 14.

Artigo em Inglês | MEDLINE | ID: mdl-37714134

2.

The Born in Guangzhou Cohort Study enables generational genetic discoveries.

Huang, Shujia; Liu, Siyang; Huang, Mingxi; He, Jian-Rong; Wang, Chengrui; Wang, Tianyi; Feng, Xiaotian; Kuang, Yashu; Lu, Jinhua; Gu, Yuqin; Xia, Xiaoyan; Lin, Shanshan; Zhou, Wenhao; Fu, Qiaomei; Xia, Huimin; Qiu, Xiu.

Nature ; 626(7999): 565-573, 2024 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-38297123

3.

Quasi-experimental evaluation of a nationwide diabetes prevention programme.

Lemp, Julia M; Bommer, Christian; Xie, Min; Michalik, Felix; Jani, Anant; Davies, Justine I; Bärnighausen, Till; Vollmer, Sebastian; Geldsetzer, Pascal.

Nature ; 624(7990): 138-144, 2023 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-37968391

4.

Inhibition of ASGR1 decreases lipid levels by promoting cholesterol excretion.

Wang, Ju-Qiong; Li, Liang-Liang; Hu, Ao; Deng, Gang; Wei, Jian; Li, Yun-Feng; Liu, Yuan-Bin; Lu, Xiao-Yi; Qiu, Zhi-Ping; Shi, Xiong-Jie; Zhao, Xiaolu; Luo, Jie; Song, Bao-Liang.

Nature ; 608(7922): 413-420, 2022 08.

Artigo em Inglês | MEDLINE | ID: mdl-35922515

5.

Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes.

Hindy, George; Dornbos, Peter; Chaffin, Mark D; Liu, Dajiang J; Wang, Minxian; Selvaraj, Margaret Sunitha; Zhang, David; Park, Joseph; Aguilar-Salinas, Carlos A; Antonacci-Fulton, Lucinda; Ardissino, Diego; Arnett, Donna K; Aslibekyan, Stella; Atzmon, Gil; Ballantyne, Christie M; Barajas-Olmos, Francisco; Barzilai, Nir; Becker, Lewis C; Bielak, Lawrence F; Bis, Joshua C; Blangero, John; Boerwinkle, Eric; Bonnycastle, Lori L; Bottinger, Erwin; Bowden, Donald W; Bown, Matthew J; Brody, Jennifer A; Broome, Jai G; Burtt, Noël P; Cade, Brian E; Centeno-Cruz, Federico; Chan, Edmund; Chang, Yi-Cheng; Chen, Yii-Der I; Cheng, Ching-Yu; Choi, Won Jung; Chowdhury, Rajiv; Contreras-Cubas, Cecilia; Córdova, Emilio J; Correa, Adolfo; Cupples, L Adrienne; Curran, Joanne E; Danesh, John; de Vries, Paul S; DeFronzo, Ralph A; Doddapaneni, Harsha; Duggirala, Ravindranath; Dutcher, Susan K; Ellinor, Patrick T; Emery, Leslie S.

Am J Hum Genet ; 109(1): 81-96, 2022 01 06.

Artigo em Inglês | MEDLINE | ID: mdl-34932938

6.

Lipidomic risk scores are independent of polygenic risk scores and can predict incidence of diabetes and cardiovascular disease in a large population cohort.

Lauber, Chris; Gerl, Mathias J; Klose, Christian; Ottosson, Filip; Melander, Olle; Simons, Kai.

PLoS Biol ; 20(3): e3001561, 2022 03.

Artigo em Inglês | MEDLINE | ID: mdl-35239643

7.

An integrative systems genetic analysis of mammalian lipid metabolism.

Parker, Benjamin L; Calkin, Anna C; Seldin, Marcus M; Keating, Michael F; Tarling, Elizabeth J; Yang, Pengyi; Moody, Sarah C; Liu, Yingying; Zerenturk, Eser J; Needham, Elise J; Miller, Matthew L; Clifford, Bethan L; Morand, Pauline; Watt, Matthew J; Meex, Ruth C R; Peng, Kang-Yu; Lee, Richard; Jayawardana, Kaushala; Pan, Calvin; Mellett, Natalie A; Weir, Jacquelyn M; Lazarus, Ross; Lusis, Aldons J; Meikle, Peter J; James, David E; de Aguiar Vallim, Thomas Q; Drew, Brian G.

Nature ; 567(7747): 187-193, 2019 03.

Artigo em Inglês | MEDLINE | ID: mdl-30814737

8.

Lipid metabolism during pregnancy: consequences for mother and child.

Mulder, Janneke W C M; Kusters, D Meeike; Roeters van Lennep, Jeanine E; Hutten, Barbara A.

Curr Opin Lipidol ; 35(3): 133-140, 2024 Jun 01.

Artigo em Inglês | MEDLINE | ID: mdl-38408036

9.

Causal association of blood lipids with all-cause and cause-specific mortality risk: a Mendelian randomization study.

Lu, Jiawen; Wang, Zhenqian; Zhang, Jiaying; Jiao, Feng; Zou, Chenfeng; Han, Liyuan; Jiang, Guozhi.

J Lipid Res ; 65(4): 100528, 2024 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-38458338

10.

Transgenic mice lacking FGF15/19-SHP phosphorylation display altered bile acids and gut bacteria, promoting nonalcoholic fatty liver disease.

Kim, Young-Chae; Qi, Ming; Dong, Xingchen; Seok, Sunmi; Sun, Hao; Kemper, Byron; Fu, Ting; Kemper, Jongsook Kim.

J Biol Chem ; 299(8): 104946, 2023 08.

Artigo em Inglês | MEDLINE | ID: mdl-37348559

11.

Once-Weekly Semaglutide in Adults with Overweight or Obesity.

Wilding, John P H; Batterham, Rachel L; Calanna, Salvatore; Davies, Melanie; Van Gaal, Luc F; Lingvay, Ildiko; McGowan, Barbara M; Rosenstock, Julio; Tran, Marie T D; Wadden, Thomas A; Wharton, Sean; Yokote, Koutaro; Zeuthen, Niels; Kushner, Robert F.

N Engl J Med ; 384(11): 989-1002, 2021 03 18.

Artigo em Inglês | MEDLINE | ID: mdl-33567185

12.

Modulation of lipid profile by secretory phospholipase A2 group IIA: Verification with a transgenic mouse model.

Liang, Ling; Song, Jing; Miao, Shisheng; Xie, Qiang; Li, Weihua; Huang, Honglang; Shen, Dongyan; Zhang, Wei.

Biochem Biophys Res Commun ; 712-713: 149955, 2024 Jun 18.

Artigo em Inglês | MEDLINE | ID: mdl-38640737

13.

Lipidomic studies revealing serological markers associated with the occurrence of retinopathy in type 2 diabetes.

He, Mingqian; Hou, Guixue; Liu, Mengmeng; Peng, Zhaoyi; Guo, Hui; Wang, Yue; Sui, Jing; Liu, Hui; Yin, Xiaoming; Zhang, Meng; Chen, Ziyi; Rensen, Patrick C N; Lin, Liang; Wang, Yanan; Shi, Bingyin.

J Transl Med ; 22(1): 448, 2024 May 13.

Artigo em Inglês | MEDLINE | ID: mdl-38741137

14.

Comparison of Clinical Decision Support Tools to Improve Pediatric Lipid Screening.

Goren, Amir; Santos, Henri C; Davis, Thomas W; Lowe, Robert B; Monfette, Mariya; Meyer, Michelle N; Chabris, Christopher F.

J Pediatr ; 269: 113973, 2024 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-38401785

15.

Lipidomics random forest algorithm of seminal plasma is a promising method for enhancing the diagnosis of necrozoospermia.

Deng, Tianqin; Wang, Wanxue; Fu, Zhihong; Xie, Yuli; Zhou, Yonghong; Pu, Jiangbo; Chen, Kexin; Yao, Bing; Li, Xuemei; Yao, Jilong.

Metabolomics ; 20(3): 57, 2024 May 21.

Artigo em Inglês | MEDLINE | ID: mdl-38773045

16.

Data-dependent and -independent acquisition lipidomics analysis reveals the tissue-dependent effect of metformin on lipid metabolism.

Scheidemantle, Grace; Duan, Likun; Lodge, Mareca; Cummings, Magdalina J; Hilovsky, Dalton; Pham, Eva; Wang, Xiaoqiu; Kennedy, Arion; Liu, Xiaojing.

Metabolomics ; 20(3): 53, 2024 May 09.

Artigo em Inglês | MEDLINE | ID: mdl-38722395

17.

Metabolic self-feeding in HBV-associated hepatocarcinoma centered on feedback between circulation lipids and the cellular MAPK/mTOR axis.

Zhu, Ying; Zhao, Yingke; Ning, Zhouyu; Deng, Yong; Li, Bing; Sun, Yun; Meng, Zhiqiang.

Cell Commun Signal ; 22(1): 280, 2024 May 21.

Artigo em Inglês | MEDLINE | ID: mdl-38773448

18.

Integration of clinical phenoms and metabolomics facilitates precision medicine for lung cancer.

Yan, Furong; Liu, Chanjuan; Song, Dongli; Zeng, Yiming; Zhan, Yanxia; Zhuang, Xibing; Qiao, Tiankui; Wu, Duojiao; Cheng, Yunfeng; Chen, Hao.

Cell Biol Toxicol ; 40(1): 25, 2024 May 01.

Artigo em Inglês | MEDLINE | ID: mdl-38691184

19.

Cross-Sectional Associations between Prenatal Per- and Poly-Fluoroalkyl Substances and Bioactive Lipids in Three Environmental Influences on Child Health Outcomes (ECHO) Cohorts.

Suthar, Himal; Manea, Tomás; Pak, Dominic; Woodbury, Megan; Eick, Stephanie M; Cathey, Amber; Watkins, Deborah J; Strakovsky, Rita S; Ryva, Brad A; Pennathur, Subramaniam; Zeng, Lixia; Weller, David; Park, June-Soo; Smith, Sabrina; DeMicco, Erin; Padula, Amy; Fry, Rebecca C; Mukherjee, Bhramar; Aguiar, Andrea; Geiger, Sarah Dee; Ng, Shukhan; Huerta-Montanez, Gredia; Vélez-Vega, Carmen; Rosario, Zaira; Cordero, Jose F; Zimmerman, Emily; Woodruff, Tracey J; Morello-Frosch, Rachel; Schantz, Susan L; Meeker, John D; Alshawabkeh, Akram N; Aung, Max T.

Environ Sci Technol ; 58(19): 8264-8277, 2024 May 14.

Artigo em Inglês | MEDLINE | ID: mdl-38691655

20.

Lipids as potential mediators linking body mass index to diabetes: evidence from a mediation analysis based on the NAGALA cohort.

Lu, Song; Wang, Qun; Lu, Hengcheng; Kuang, Maobin; Zhang, Min; Sheng, Guotai; Zou, Yang; Peng, Xiaoping.

BMC Endocr Disord ; 24(1): 66, 2024 May 10.

Artigo em Inglês | MEDLINE | ID: mdl-38730299

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