Pesquisa | Biblioteca Virtual em Saúde

1.

A trispecific antibody targeting HER2 and T cells inhibits breast cancer growth via CD4 cells.

Seung, Edward; Xing, Zhen; Wu, Lan; Rao, Ercole; Cortez-Retamozo, Virna; Ospina, Beatriz; Chen, Liqing; Beil, Christian; Song, Zhili; Zhang, Bailin; Levit, Mikhail; Deng, Gejing; Hebert, Andrew; Kirby, Patrick; Li, Aiqun; Poulton, Emma-Jane; Vicente, Rita; Garrigou, Audrey; Piepenhagen, Peter; Ulinski, Greg; Sanicola-Nadel, Michele; Bangari, Dinesh S; Qiu, Huawei; Pao, Lily; Wiederschain, Dmitri; Wei, Ronnie; Yang, Zhi-Yong; Nabel, Gary J.

Nature ; 603(7900): 328-334, 2022 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-35197632

2.

Cancer-stromal cell interactions in breast cancer brain metastases induce glycocalyx-mediated resistance to HER2-targeting therapies.

Goyette, Marie-Anne; Stevens, Laura E; DePinho, Carolyn R; Seehawer, Marco; Nishida, Jun; Li, Zheqi; Wilde, Callahan M; Li, Rong; Qiu, Xintao; Pyke, Alanna L; Zhao, Stephanie; Lim, Klothilda; Tender, Gabrielle S; Northey, Jason J; Riley, Nicholas M; Long, Henry W; Bertozzi, Carolyn R; Weaver, Valerie M; Polyak, Kornelia.

Proc Natl Acad Sci U S A ; 121(20): e2322688121, 2024 May 14.

Artigo em Inglês | MEDLINE | ID: mdl-38709925

3.

ESR1 gene amplification and MAP3K mutations are selected during adjuvant endocrine therapies in relapsing Hormone Receptor-positive, HER2-negative breast cancer (HR+ HER2- BC).

Ferrando, Lorenzo; Vingiani, Andrea; Garuti, Anna; Vernieri, Claudio; Belfiore, Antonino; Agnelli, Luca; Dagrada, Gianpaolo; Ivanoiu, Diana; Bonizzi, Giuseppina; Munzone, Elisabetta; Lippolis, Luana; Dameri, Martina; Ravera, Francesco; Colleoni, Marco; Viale, Giuseppe; Magnani, Luca; Ballestrero, Alberto; Zoppoli, Gabriele; Pruneri, Giancarlo.

PLoS Genet ; 19(1): e1010563, 2023 01.

Artigo em Inglês | MEDLINE | ID: mdl-36595552

4.

Knockout of all ErbB-family genes delineates their roles in proliferation, survival and migration.

Matsuda, Kimiya; Hirayama, Daiki; Hino, Naoya; Kuno, Sota; Sakaue-Sawano, Asako; Miyawaki, Atsushi; Matsuda, Michiyuki; Terai, Kenta.

J Cell Sci ; 136(16)2023 08 15.

Artigo em Inglês | MEDLINE | ID: mdl-37519219

5.

Trastuzumab Deruxtecan in HER2-Mutant Non-Small-Cell Lung Cancer.

Li, Bob T; Smit, Egbert F; Goto, Yasushi; Nakagawa, Kazuhiko; Udagawa, Hibiki; Mazières, Julien; Nagasaka, Misako; Bazhenova, Lyudmila; Saltos, Andreas N; Felip, Enriqueta; Pacheco, Jose M; Pérol, Maurice; Paz-Ares, Luis; Saxena, Kapil; Shiga, Ryota; Cheng, Yingkai; Acharyya, Suddhasatta; Vitazka, Patrik; Shahidi, Javad; Planchard, David; Jänne, Pasi A.

N Engl J Med ; 386(3): 241-251, 2022 01 20.

Artigo em Inglês | MEDLINE | ID: mdl-34534430

6.

Trastuzumab Deruxtecan in Previously Treated HER2-Low Advanced Breast Cancer.

Modi, Shanu; Jacot, William; Yamashita, Toshinari; Sohn, Joohyuk; Vidal, Maria; Tokunaga, Eriko; Tsurutani, Junji; Ueno, Naoto T; Prat, Aleix; Chae, Yee Soo; Lee, Keun Seok; Niikura, Naoki; Park, Yeon Hee; Xu, Binghe; Wang, Xiaojia; Gil-Gil, Miguel; Li, Wei; Pierga, Jean-Yves; Im, Seock-Ah; Moore, Halle C F; Rugo, Hope S; Yerushalmi, Rinat; Zagouri, Flora; Gombos, Andrea; Kim, Sung-Bae; Liu, Qiang; Luo, Ting; Saura, Cristina; Schmid, Peter; Sun, Tao; Gambhire, Dhiraj; Yung, Lotus; Wang, Yibin; Singh, Jasmeet; Vitazka, Patrik; Meinhardt, Gerold; Harbeck, Nadia; Cameron, David A.

N Engl J Med ; 387(1): 9-20, 2022 07 07.

Artigo em Inglês | MEDLINE | ID: mdl-35665782

7.

Decreased HER2 expression in endometrial cancer following anti-HER2 therapy.

Chui, M Herman; Brown, David N; Da Cruz Paula, Arnaud; da Silva, Edaise M; Momeni-Boroujeni, Amir; Reis-Filho, Jorge S; Zhang, Yanming; Makker, Vicky; Ellenson, Lora Hedrick; Weigelt, Britta.

J Pathol ; 262(2): 129-136, 2024 02.

Artigo em Inglês | MEDLINE | ID: mdl-38013631

8.

Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups.

Rueda, Oscar M; Sammut, Stephen-John; Seoane, Jose A; Chin, Suet-Feung; Caswell-Jin, Jennifer L; Callari, Maurizio; Batra, Rajbir; Pereira, Bernard; Bruna, Alejandra; Ali, H Raza; Provenzano, Elena; Liu, Bin; Parisien, Michelle; Gillett, Cheryl; McKinney, Steven; Green, Andrew R; Murphy, Leigh; Purushotham, Arnie; Ellis, Ian O; Pharoah, Paul D; Rueda, Cristina; Aparicio, Samuel; Caldas, Carlos; Curtis, Christina.

Nature ; 567(7748): 399-404, 2019 03.

Artigo em Inglês | MEDLINE | ID: mdl-30867590

9.

Tyrosine phosphorylation-mediated YAP1-TFAP2A interactions coordinate transcription and trastuzumab resistance in HER2+ breast cancer.

Zou, Hailin; Luo, Juan; Guo, Yibo; Deng, Liang; Zeng, Leli; Pan, Yihang; Li, Peng.

Drug Resist Updat ; 73: 101051, 2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-38219531

10.

IFI16-dependent STING signaling is a crucial regulator of anti-HER2 immune response in HER2+ breast cancer.

Ong, Li-Teng; Lee, Wee Chyan; Ma, Shijun; Oguz, Gokce; Niu, Zhitong; Bao, Yi; Yusuf, Mubaraka; Lee, Puay Leng; Goh, Jian Yuan; Wang, Panpan; Yong, Kylie Su Mei; Chen, Qingfeng; Wang, Wenyu; Ramasamy, Adaikalavan; Hoon, Dave S B; Ditzel, Henrik J; Tan, Ern Yu; Lee, Soo Chin; Yu, Qiang.

Proc Natl Acad Sci U S A ; 119(31): e2201376119, 2022 08 02.

Artigo em Inglês | MEDLINE | ID: mdl-35878022

11.

Activity and safety of enobosarm, a novel, oral, selective androgen receptor modulator, in androgen receptor-positive, oestrogen receptor-positive, and HER2-negative advanced breast cancer (Study G200802): a randomised, open-label, multicentre, multinational, parallel design, phase 2 trial.

Palmieri, Carlo; Linden, Hannah; Birrell, Stephen N; Wheelwright, Sally; Lim, Elgene; Schwartzberg, Lee S; Dwyer, Amy R; Hickey, Theresa E; Rugo, Hope S; Cobb, Patrick; O'Shaughnessy, Joyce A; Johnston, Stephen; Brufsky, Adam; Tilley, Wayne D; Overmoyer, Beth.

Lancet Oncol ; 25(3): 317-325, 2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-38342115

12.

Trastuzumab deruxtecan in patients with metastatic non-small-cell lung cancer (DESTINY-Lung01): primary results of the HER2-overexpressing cohorts from a single-arm, phase 2 trial.

Smit, Egbert F; Felip, Enriqueta; Uprety, Dipesh; Nagasaka, Misako; Nakagawa, Kazuhiko; Paz-Ares Rodríguez, Luis; Pacheco, Jose M; Li, Bob T; Planchard, David; Baik, Christina; Goto, Yasushi; Murakami, Haruyasu; Saltos, Andreas; Pereira, Kaline; Taguchi, Ayumi; Cheng, Yingkai; Yan, Qi; Feng, Wenqin; Tsuchihashi, Zenta; Jänne, Pasi A.

Lancet Oncol ; 25(4): 439-454, 2024 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-38547891

13.

A phase 1b study of zilovertamab in combination with paclitaxel for locally advanced/unresectable or metastatic Her2-negative breast cancer.

Shatsky, Rebecca A; Batra-Sharma, Hemali; Helsten, Teresa; Schwab, Richard B; Pittman, Emily I; Pu, Minya; Weihe, Elizabeth; Ghia, Emanuela M; Rassenti, Laura Z; Molinolo, Alfredo; Cabrera, Betty; Breitmeyer, James B; Widhopf, George F; Messer, Karen; Jamieson, Catriona; Kipps, Thomas J; Parker, Barbara A.

Breast Cancer Res ; 26(1): 32, 2024 02 26.

Artigo em Inglês | MEDLINE | ID: mdl-38408999

14.

c-MET-positive circulating tumor cells and cell-free DNA as independent prognostic factors in hormone receptor-positive/HER2-negative metastatic breast cancer.

Park, Jieun; Chang, Eun Sol; Kim, Ji-Yeon; Chelakkot, Chaithanya; Sung, Minjung; Song, Ji-Young; Jung, Kyungsoo; Lee, Ji Hye; Choi, Jun Young; Kim, Na Young; Lee, Hyegyeong; Kang, Mi-Ran; Kwon, Mi Jeong; Shin, Young Kee; Park, Yeon Hee; Choi, Yoon-La.

Breast Cancer Res ; 26(1): 13, 2024 01 18.

Artigo em Inglês | MEDLINE | ID: mdl-38238761

15.

ADAMTS18 deficiency associates extracellular matrix dysfunction with a higher risk of HER2-positive mammary tumorigenesis and metastasis.

Nie, Jiahui; Dang, Suying; Zhu, Rui; Lu, Tiantian; Zhang, Wei.

Breast Cancer Res ; 26(1): 19, 2024 01 29.

Artigo em Inglês | MEDLINE | ID: mdl-38287441

16.

Clustering of HR + /HER2- breast cancer in an Asian cohort is driven by immune phenotypes.

Pan, Jia-Wern; Ragu, Mohana; Chan, Wei-Qin; Hasan, Siti Norhidayu; Islam, Tania; Teoh, Li-Ying; Jamaris, Suniza; See, Mee-Hoong; Yip, Cheng-Har; Rajadurai, Pathmanathan; Looi, Lai-Meng; Taib, Nur Aishah Mohd; Rueda, Oscar M; Caldas, Carlos; Chin, Suet-Feung; Lim, Joanna; Teo, Soo-Hwang.

Breast Cancer Res ; 26(1): 67, 2024 Apr 22.

Artigo em Inglês | MEDLINE | ID: mdl-38649964

17.

In ER-Positive, HER2-Negative Breast Cancers, HER2 mRNA Levels Correlate Better with Clinicopathologic Features and Oncotype DX Recurrence Score than HER2 Immunohistochemistry.

Tyburski, Haley; Karakas, Cansu; Finkelman, Brian S; Turner, Bradley M; Zhang, Huina; Hicks, David G.

Lab Invest ; 104(3): 100309, 2024 03.

Artigo em Inglês | MEDLINE | ID: mdl-38135156

18.

MRI-based tumor shrinkage patterns after early neoadjuvant therapy in breast cancer: correlation with molecular subtypes and pathological response after therapy.

Wang, Mengfan; Du, Siyao; Gao, Si; Zhao, Ruimeng; Liu, Shasha; Jiang, Wenhong; Peng, Can; Chai, Ruimei; Zhang, Lina.

Breast Cancer Res ; 26(1): 26, 2024 02 12.

Artigo em Inglês | MEDLINE | ID: mdl-38347619

19.

NSABP FB-10: a phase Ib/II trial evaluating ado-trastuzumab emtansine (T-DM1) with neratinib in women with metastatic HER2-positive breast cancer.

Jacobs, Samuel A; Wang, Ying; Abraham, Jame; Feng, Huichen; Montero, Alberto J; Lipchik, Corey; Finnigan, Melanie; Jankowitz, Rachel C; Salkeni, Mohamad A; Maley, Sai K; Puhalla, Shannon L; Piette, Fanny; Quinn, Katie; Chang, Kyle; Nagy, Rebecca J; Allegra, Carmen J; Vehec, Kelly; Wolmark, Norman; Lucas, Peter C; Srinivasan, Ashok; Pogue-Geile, Katherine L.

Breast Cancer Res ; 26(1): 69, 2024 Apr 22.

Artigo em Inglês | MEDLINE | ID: mdl-38650031

20.

Age-related phenotypes in breast cancer: A population-based study.

Svanøe, Amalie A; Humlevik, Rasmus O C; Knutsvik, Gøril; Sæle, Anna K M; Askeland, Cecilie; Ingebriktsen, Lise M; Hugaas, Ulrikke; Kvamme, Amalie B; Tegnander, Amalie F; Krüger, Kristi; Davidsen, Benedicte; Hoivik, Erling A; Aas, Turid; Stefansson, Ingunn M; Akslen, Lars A; Wik, Elisabeth.

Int J Cancer ; 154(11): 2014-2024, 2024 Jun 01.

Artigo em Inglês | MEDLINE | ID: mdl-38319154

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