Bioactive constituents from gum guggul (Commiphora wightii).
Phytochemistry
; 56(7): 723-7, 2001 Apr.
Article
em En
| MEDLINE
| ID: mdl-11314959
ABSTRACT
Bioactivity-directed fractionation and purification afforded cytotoxic components of Commiphora wightii. The exudates of C. wightii were extracted with EtOAc and the extract was subjected to repeated column chromatography. A fraction showing cytotoxic activity was characterized as a mixture of two ferulates with an unusual skeleton by spectral and chemical methods, including by NMR, GC-MS and chemical derivatization. This fraction also showed moderate scavenging effect against 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Limite:
Female
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2001
Tipo de documento:
Article