Novel nucleotide phosphonate analogues with potent antitumor activity.
Bioorg Med Chem Lett
; 12(21): 3063-6, 2002 Nov 04.
Article
em En
| MEDLINE
| ID: mdl-12372502
We have identified several nucleotide phosphonates demonstrating in vitro antiproliferative activity in several human cancer cell lines with IC(50) values in the microM range. The synthesis as well as structure-activity relationship are described.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Limite:
Humans
Idioma:
En
Ano de publicação:
2002
Tipo de documento:
Article