Total synthesis of (+)-spongistatin 1. An effective second-generation construction of an advanced EF Wittig salt, fragment union, and final elaboration.

Smith, Amos B; Zhu, Wenyu; Shirakami, Shohei; Sfouggatakis, Chris; Doughty, Victoria A; Bennett, Clay S; Sakamoto, Yasuharu

Smith, Amos B; Zhu, Wenyu; Shirakami, Shohei; Sfouggatakis, Chris; Doughty, Victoria A; Bennett, Clay S; Sakamoto, Yasuharu.

Afiliação

Smith AB; Department of Chemistry, Monell Chemical Senses Center, Laboratory for Research on the Structure of Matter, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

Org Lett ; 5(5): 761-4, 2003 Mar 06.

Article em En | MEDLINE | ID: mdl-12605509

Assuntos

Antineoplásicos/síntese química; Éteres Cíclicos/síntese química; Lactonas/síntese química; Macrolídeos; Aldeídos/química; Lactonas/química; Estereoisomerismo

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