Decomposing protein networks into domain-domain interactions.
Bioinformatics
; 21 Suppl 2: ii220-1, 2005 Sep 01.
Article
em En
| MEDLINE
| ID: mdl-16204107
ABSTRACT
UNLABELLED The application of novel experimental techniques has generated large networks of protein-protein interactions. Frequently, important information on the structure and cellular function of protein-protein interactions can be gained from the domains of interacting proteins. We have designed a Cytoscape plugin that decomposes interacting proteins into their respective domains and computes a putative network of corresponding domain-domain interactions. To this end, the network graph of proteins has been extended by additional node and edge types for domain interactions, including different node and edge shapes and coloring schemes used for visualization. An additional plugin provides supplementary web links to Internet resources on domain function and structure. AVAILABILITY:
Both Cytoscape plugins can be downloaded from http//www.cytoscape.org
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article