Ginsenoside Re attenuate beta-amyloid and serum-free induced neurotoxicity in PC12 cells.
J Ethnopharmacol
; 107(1): 48-52, 2006 Aug 11.
Article
em En
| MEDLINE
| ID: mdl-16564145
ABSTRACT
AIM:
To study the effect of ginsenoside Re on PC12 cell damage induced by serum deprivation and beta-amyloid peptide.METHODS:
PC 12 cell survival was measured by MTT and lactate dehydrogenase (LDH) assay. Results Serum-free medium and beta-amyloid peptide (10-100 microM) induced cytotoxicity in PC 12 cells. Ginsenoside Re (0.1-100 microM) attenuated the cytotoxic effects of serum-free medium and beta-amyloid peptide (50 microM) in a concentration-dependent manner.CONCLUSION:
Ginsenoside Re prevented PC 12 cells from lesion induced by serum-free medium and beta-amyloid peptide.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Limite:
Animals
Idioma:
En
Ano de publicação:
2006
Tipo de documento:
Article