DNA methyl transferase inhibiting halogenated monoterpenes from the Madagascar red marine alga Portieria hornemannii.
J Nat Prod
; 69(4): 576-9, 2006 Apr.
Article
em En
| MEDLINE
| ID: mdl-16643029
ABSTRACT
Three new halogenated monoterpenes, 2, 3, and 4, along with the known compounds halomon (1) and two analogues, 5 and 6, were isolated from the Madagascar red marine alga Portieria hornemannii. The structures of all three new compounds were determined by NMR spectroscopy in combination with mass spectrometric data analysis. Two of these monoterpenes (1 and 2) were low micromolar inhibitors of DNA methyl transferase-1.
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01-internacional
Base de dados:
MEDLINE
País/Região como assunto:
Africa
Idioma:
En
Ano de publicação:
2006
Tipo de documento:
Article