Alpha,beta-D-CNA induced rigidity within oligonucleotides.
Org Biomol Chem
; 6(16): 2849-51, 2008 Aug 21.
Article
em En
| MEDLINE
| ID: mdl-18688476
Introduction of alpha,beta-D-CNA featuring canonical values of the torsional angles alpha and beta within oligonucleotides leads to an overall stabilization and improved rigidity of the duplex DNA as demonstrated by UV experiments, circular dichroism and corroborated by molecular dynamics simulations.
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01-internacional
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MEDLINE
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article