Apoptosis in the trabecular meshwork of glaucomatous patients.
Mol Vis
; 14: 1513-6, 2008 Aug 18.
Article
em En
| MEDLINE
| ID: mdl-18728789
ABSTRACT
We established and validated an in toto method to perform TdT-mediated dUTP nick end labeling to study apoptosis in human trabecular meshwork tissue obtained during trabeculectomy in glaucoma patients. In specimens from patients with primary open-angle glaucoma and primary angle-closure glaucoma, we detected a tendency for more apoptotic cells to accumulate in patients with primary open-angle glaucoma. The utility of this method to study apoptosis in the trabecular meshwork is discussed, as well as its application as a tool in biologic samples.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Limite:
Aged
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Aged80
/
Humans
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Middle aged
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article