MicroRNAs: new players in acute myeloid leukaemia.

Havelange, V; Garzon, R; Croce, C M

Havelange, V; Garzon, R; Croce, C M.

Afiliação

Havelange V; Department of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.

Br J Cancer ; 101(5): 743-8, 2009 Sep 01.

Article em En | MEDLINE | ID: mdl-19672257

ABSTRACT

ABSTRACT

MicroRNAs (miRNAs) are short non-coding RNAs that have key functions in a wide array of critical cell processes, including haematopoiesis by regulating the expression of multiple genes. Aberrant miRNA expression has been described in acute myeloid leukaemia suggesting a role in leukaemogenesis. In this review we summarise the current knowledge.

Assuntos

Leucemia Mieloide Aguda/genética; MicroRNAs/genética; MicroRNAs/metabolismo; Humanos; Leucemia Mieloide Aguda/diagnóstico; Leucemia Mieloide Aguda/metabolismo; Leucemia Mieloide Aguda/terapia; Prognóstico

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2009 Tipo de documento: Article

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