[A rare case of small-cell diffuse invasive breast lobular carcinoma].

ABSTRACT

The paper describes a rare case of invasive lobular carcinoma with the diffuse growth type simulating malignant non-Hodgkin lymphoma. The immunohistochemical study of the tumor established a marked expression of pancytokeratin, GSDFP-15, receptors to estrogen and progesterone, CD 7, Bcl-2, expression CD 3, CD 5, CD 10, CD 20, CD 23, CD 30, ALK, Bcl-6, inactive expression of E-cadherin. The ability of invasive lobular carcinoma to simulate malignant non-Hodgkin lymphoma determines the diagnostic value and significance of an immunohistochemical study to confirm the epithelial nature of the tumor.