Factors leading to obstructive granulation tissue formation after ultraflex stenting in benign tracheal narrowing.
Thorac Cardiovasc Surg
; 58(2): 102-7, 2010 Mar.
Article
em En
| MEDLINE
| ID: mdl-20333573
ABSTRACT
BACKGROUND:
This retrospective study aimed to determine the factors leading to obstructive granulation tissue formation after the placement of a self-expandable metallic stent (SEMS) in patients with benign tracheal disease.METHODS:
From 2001 to 2007, a total of 67 patients (age 62.1 +/- 15.4 years; range 23-87 years) with benign tracheal disease received 75 ultraflex SEMS in our institution.RESULTS:
There were 35 SEMSs complicated by obstructive granulation tissue formation out of the 75 stents placed in patients with tracheal disease, giving an incidence of 47.8 % (32/67 patients). The median time until developing granulation tissue was 106 days (IQR, 46-396). Structural airway obstruction prior to SEMS implantation independently predicted obstructive granulation tissue formation after SEMS implantation (odds ratio 3.84; 95 % CI 1.01-8.7; P = 0.04). Time to granulation tissue detection was shorter in patients with structural airway obstruction before SEMS implantation (structural airway obstruction vs. dynamic collapse airway median [IQR] 95 [38-224, n = 26] vs. 396 days [73-994, n = 9]; P = 0.02).CONCLUSIONS:
Obstructive granulation tissue formation is not uncommon after SEMS implantation and structural airway obstruction prior to SEMS implantation is an independent predictor. Although SEMS implantation should be restricted to a select population, it may be placed in patients not suitable for surgical intervention or rigid bronchoscopy with anesthesia because of poor pulmonary function.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Diagnostic_studies
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Etiology_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adult
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Aged
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Aged80
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Humans
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Middle aged
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article