Extremely elevated erythrocyte sedimentation rate: etiology at a tertiary care center in Saudi Arabia.
Saudi Med J
; 31(11): 1227-31, 2010 Nov.
Article
em En
| MEDLINE
| ID: mdl-21063653
ABSTRACT
OBJECTIVE:
To evaluate the etiology of extremely elevated erythrocyte sedimentation rate (ESR) in adolescents and adults at a tertiary care center.METHODS:
This retrospective, cross-sectional, observational study was carried out at King Abdulaziz Medical City, Riyadh, Saudi Arabia using the Westergren method of determining ESR in adolescents and adults aged >or=12 years. The patients included inpatients and outpatients with medical, surgical, and gynecological problems. During a period from June 2007 to October 2008, consecutive, non-repetitive patients with ESR >or=100 mm/hour were evaluated for possible etiology by checking the electronic and paper data file of each patient.RESULTS:
During the study period, out of the 44,366 ESR tests carried out at this center, 1864 (4.2%) had an ESR >or=100 mm/hour belonging to 567 patients. Out of 508 patients fulfilling the study criteria, the main associated causes included infections (38.6%), autoimmune diseases (15.9%), malignancy (15.4%), miscellaneous causes (10.2%), ischemic tissue injury or trauma (8.7%), and renal diseases (8.4%). Ten common individual causes included rheumatoid arthritis (7.3%), osteomyelitis (6.9%), tuberculosis (5.5%), trauma (5.3%), lymphoma and sepsis of unknown origin (5.1%) each, urinary tract infection (4.7%), septic arthritis (3.1%), abscesses (2.8%), and pregnancy (2.2%). Fourteen (2.4%) patients had no known cause.CONCLUSION:
Most of the patients with extreme ESR elevation have an underlying cause and a focused evaluation of such patients needs to be carried out to reach a diagnosis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Humans
País/Região como assunto:
Asia
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article