Ca2+ influx through reverse mode Na+/Ca2+ exchange is critical for vascular endothelial growth factor-mediated extracellular signal-regulated kinase (ERK) 1/2 activation and angiogenic functions of human endothelial cells.

Andrikopoulos, Petros; Baba, Akemichi; Matsuda, Toshio; Djamgoz, Mustafa B A; Yaqoob, Muhammad M; Eccles, Suzanne A

Andrikopoulos, Petros; Baba, Akemichi; Matsuda, Toshio; Djamgoz, Mustafa B A; Yaqoob, Muhammad M; Eccles, Suzanne A.

Afiliação

Andrikopoulos P; Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, McElwain Laboratories, Cotswold Road, Belmont, Sutton, Surrey SM2 5NG, United Kingdom; Division of Cell and Molecular Biology, Neuroscience Solutions to Cancer Research Group, Imperial College London, London SW7 2AZ, Unit
Baba A; Laboratory of Medicinal Pharmacology, Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamada-oka, Suita, Osaka 565-0871.
Matsuda T; Laboratory of Medicinal Pharmacology, Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamada-oka, Suita, Osaka 565-0871.
Djamgoz MBA; Division of Cell and Molecular Biology, Neuroscience Solutions to Cancer Research Group, Imperial College London, London SW7 2AZ, United Kingdom.
Yaqoob MM; Translational Medicine and Therapeutics, William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary's University of London, London EC1M 6BQ, United Kingdom.
Eccles SA; Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, McElwain Laboratories, Cotswold Road, Belmont, Sutton, Surrey SM2 5NG, United Kingdom. Electronic address: sue.eccles@icr.ac.uk.

J Biol Chem ; 286(44): 37919-37931, 2011 Nov 04.

Article em En | MEDLINE | ID: mdl-21873429

Assuntos

Cálcio/metabolismo; Células Endoteliais/citologia; Proteína Quinase 1 Ativada por Mitógeno/metabolismo; Proteína Quinase 3 Ativada por Mitógeno/metabolismo; Neovascularização Patológica; Trocador de Sódio e Cálcio/metabolismo; Fator A de Crescimento do Endotélio Vascular/metabolismo; Proliferação de Células; Células Cultivadas; Inativação Gênica; Humanos; Íons; Fosforilação; Proteína Quinase C-alfa/metabolismo; Veias Umbilicais/citologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2011 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2011 Tipo de documento: Article