HDAC3 at the fulcrum of an epithelial-mesenchymal balance.
Mol Cell
; 43(5): 697-8, 2011 Sep 02.
Article
em En
| MEDLINE
| ID: mdl-21884971
ABSTRACT
In this issue of Molecular Cell, Wu et al. (2011) reveal an essential role for a chromatin modifier, histone deacetylase 3 (HDAC3), in hypoxia-induced epithelial-mesenchymal transition (EMT); HIF-activated HDAC3 integrates with WDR5 to impose chromatin modifications that culminate in EMT.
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01-internacional
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MEDLINE
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article