Inner ear supporting cells: rethinking the silent majority.
Semin Cell Dev Biol
; 24(5): 448-59, 2013 May.
Article
em En
| MEDLINE
| ID: mdl-23545368
ABSTRACT
Sensory epithelia of the inner ear contain two major cell types hair cells and supporting cells. It has been clear for a long time that hair cells play critical roles in mechanoreception and synaptic transmission. In contrast, until recently the more abundant supporting cells were viewed as serving primarily structural and homeostatic functions. In this review, we discuss the growing information about the roles that supporting cells play in the development, function and maintenance of the inner ear, their activities in pathological states, their potential for hair cell regeneration, and the mechanisms underlying these processes.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article