From a multipotent stilbene to soluble epoxide hydrolase inhibitors with antiproliferative properties.
ChemMedChem
; 8(6): 919-23, 2013 Jun.
Article
em En
| MEDLINE
| ID: mdl-23596124
ABSTRACT
Inspired by nature Natural product isopropylstilbene was identified as an inhibitor of soluble epoxide hydrolase exhibiting antiproliferative properties. Following the natural product inspired design approach, a library of (E)-styryl-1H-benzo[d]imidazoles was synthesized and evaluated with recombinant enzyme and on several cancer cell lines.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Limite:
Humans
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article